Evaluating the effect of a mixture of alcohol and acetic acid for otomycosis therapy


Ahmad Yaganeh Moghadam 1 , Mohammad Ali Asadi 1 , Rohullah Dehghani 1 , Ali Zarei Mahmoudabadi 2 , Fariba Rayegan 1 , Hossein Hooshyar 1 , Ahmad Khorshidi 3 , *

1 Department of ENT, Kashan University of Medical Sciences, Iran

2 Department of Medical Mycology, School of Medicine, Infectious and Tropical Diseases Research Center and Ahvaz Jundishapur University of Medical Sciences, Iran

3 Department of Medical Microbiology, Kashan University of Medical Sciences, [email protected], Iran

How to Cite: Yaganeh Moghadam A, Asadi M A, Dehghani R, Zarei Mahmoudabadi A, Rayegan F, et al. Evaluating the effect of a mixture of alcohol and acetic acid for otomycosis therapy, Jundishapur J Microbiol. Online ahead of Print ; 3(2):66-70.


Jundishapur Journal of Microbiology: 3 (2); 66-70
Article Type: Research Article
Received: January 1, 2010
Accepted: March 1, 2010




Introduction and objective: Otomycosis is a fungal infection of external auditory meatus. The acute form of the disease causes secretion and pruritus. The usual prescribed medicines for otomycosis are topical clotrimazole 1%, amphotericin B and otosporin. The aim of the present study was to evaluate the efficacy of treatment with isopropyl alcohol and acetic acid for otomycosis.

Materials and methods: In the present study 910 patients examined and those suspected to have otomycosis referred to medical mycology laboratory of Golabchi, Kashan. A questionnaire was also filled for each patient. Both direct and culture examinations were used to confirm otomycosis in the patients. Then the patients were treated with the mixture of isopropyl alcohol+acetic acid.

Results: Out of 910 examined patients, 60 patients were suspected to have otomycosis and referred to medical mycology lab. Mycological examinations confirmed otomycosis in 52 patients (86.7%). Most of the patients (78.8%) were cured perfectly after therapy with the mixture of alcohol and acetic acid. After three weeks, in addition to elimination of clinical signs further smear showed no sign of disease. However in four patients there was a relapse of the disease.

Conclusion: Due to therapeutic effect of the mixture of isopropyl alcohol and acetic acid for otomycosis, its low side effects and low rate of relapse, it is recommended to use this mixture for the treatment of otomycosis.


Otomycosis, Isopropyl alcohol, Acetic acid, Aspergillus niger

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF