Study on growth of Toxoplasma gondii tissue cyst in laboratory mouse

AUTHORS

Hossein Hooshyar ORCID 1 , * , Parvin Rostamkhani 2 , Mohsen Arbabi 2 , 3

1 Department of Parasitology, School of Medicine, Kashan University of Medical Sciences, [email protected], Iran

2 Department of Parasitology, School of Medicine, Kashan University of Medical Sciences, Iran

3

How to Cite: Hooshyar H, Rostamkhani P, Arbabi M, . Study on growth of Toxoplasma gondii tissue cyst in laboratory mouse , Jundishapur J Microbiol. Online ahead of Print ; 2(4):140-143.

ARTICLE INFORMATION

Jundishapur Journal of Microbiology: 2 (4); 140-143
Article Type: Research Article
Received: July 1, 2009
Accepted: November 1, 2009

Crossmark

CHEKING

READ FULL TEXT
Abstract

Introduction and objective: Toxoplasma gondii is a widespread protozoan parasite that infects human and animals. Tissue cyst of T. gondii is an important source of human and other hosts infection including cats as definitive host. This study was carried out to determine growth of T. gondii tissue cyst in laboratory syurian mouse.

Materials and methods: Fifteen mice in three groups were infected with T. gondii by intraperitoneally inoculation. The mice of each group killed after two, three and four months. Ten smears of brains were prepared from each group and examined microscopically for Toxoplasma tissue cyst. The diameter of 17 cysts from each group was determined and recorded and the mean size in each group calculated.

Results: The mean diameters of tissue cysts were 49.4×44.8µm after two months and 64.5×55.7µ after three months of inoculation. After four months the mean diameter of tissue cyst reached to 60.6×53.48µ. The volume of tissue cysts grew within two and three months after inoculation but after four months the growth leveled off. 

Conclusion: The present study showed that the mean diameter of tissue cyst grew during the first three months and after four months became stable and some may get compacted and lesser.

Keywords

Toxoplasma gondii, Tissue cyst, Mouse

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF

COMMENTS

LEAVE A COMMENT HERE: