Central nervous system fungal infections; a review article

AUTHORS

Majid Zarrin 1 , * , Ali Zarei Mahmoudabadi 2

1 Department of Medical Mycoparasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran

2 Department of Medical Mycoparasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences-Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Iran

How to Cite: Zarrin M, Zarei Mahmoudabadi A. Central nervous system fungal infections; a review article , Jundishapur J Microbiol. Online ahead of Print ; 3(2):41-47.

ARTICLE INFORMATION

Jundishapur Journal of Microbiology: 3 (2); 41-47
Article Type: Research Article
Received: April 1, 2010
Accepted: April 1, 2010

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Abstract

Central nervous system (CNS) fungal infections have a high rate of morbidity and mortality that increased during last three decades. CNS fungal infections present a diagnostic and therapeutic challenge. High numbers of organ transplants, chemotherapy patients, intensive care unit hospitalizations, immunocompromised patients and haematological malignancies increase morbidity and mortality. Several fungi including, saprophytic fungi, melanized fungi, dimorphic fungi, yeast and yeasts-likes cause CNS fungal infections. New antifungal, posaconazole, voriconazole and echinocandins as well as traditionally antifungal, amphotericine B, flucytosine and itraconazole were used for CNS fungal infection therapy.

Keywords

CNS fungal infection, Candida, Cryptococcus, Saprophytic fungi, Dimorphic fungi

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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