Molecular Interaction and Physico-Chemical and Docking Analysis in Binary Organic Molecules at Various Temperatures

Abstract

Ultrasonic velocity (U), density (ρ), viscosity (ƞ) for the binary mixture of some biological samples in the whole range of composition has been carried out at various temperatures 278.15K to 328.15K. From the measured parameters U, ρ and ƞ some derived parameters internal pressure, free volume, rao’s constant, wada’s constant, vanderwaal’s constant, solvation number, apparent molal volume and apparent molal compressibility are also estimated. The decreasing trend of free volume, solvation number, apparent molal volume and apparent molal compressibility with concentrations and other parameters are in increasing trend were observed. The trend of acoustical and physico-chemical parameters confirm the dynamics of molecules at higher temperature and the magnitude of intermolecular interactions among the constituents of the mixtures always reflects the nature of substance. The role of apparent molar volume has been used to determine their thermal response. The sign and magnitude of these properties are evident for the nature of interactions between component molecules.