Main Article Content
Non-adherence to medication is a significant problem in chronic conditions management. Althoughseveral researchers have found spirituality and spiritualwell-being are primary resources for life satisfaction among persons with chronic disease. This study aimed to assess the correlation between medication adherence, spiritual needs, and life satisfaction among patients with chronic disease.This study used a descriptive-correlational research design; 150 patients with different chronic diseases admitted to medicaldepartments at Sohag University were recruited. The researchers collected the data using four tools:tool I: socio-demographicdata,clinical data, and lifestyle activity; tool II: Medication Adherence Scale (Morisky-8), tool III: Spiritual Well-Being Questionnaire, and tool IV: Brief Multidimensional Life Satisfaction Scale (Version 2). Tool III and IV were translated into the Arabic language. Content validity and reliability were carried out for the same tools, and Cronbach’s Alpha was 0.74, and 0.70 respectively. The researchers collected the data using a semi-structured interview.The majority were male and married (70.7 %, 87.3), more than half of participants were religious people (59.3 %). In addition,most participants (81.3 %) had Low adherence to their medications, while most (96.7 %) were highly satisfied. About Moriskymedication adherence and the Spiritual Well-Being Questionnaire Ideal personal and community domains have a strong inverse correlation, and there was a significant inverse correlation between Morisky medication adherence and life satisfaction. When a patient symbolizes or distinguishes their spiritual needs and understands the meaning of their life, all of this leads to an increase in the level of life satisfaction and the follow-up medication regimen and improves the health status of the patient.Nurses should perform spiritual assessment and well-being for patients with chronic disease, which may help identify positive or negative effects on health.