Research Progress on the Role of Mitophagy in the Occurrence and Development of Cervical Carcinoma

Abstract

Cervical carcinoma is a serious threat to women’s health. At present, sufferers with carcinoma of Cervix Uteri are received in surgery, radiotherapy, chemotherapy, etc., but one third of the treated women will relapse, which almost inevitably leads to death. The molecular mechanism of cervical carcinoma is still not known, so the pathogenesis of carcinoma of Cervix Uteri needs to be further explored. The complete removal of mitochondria is accomplished through a selective autophagy method, which is the main method for removing damaged mitochondria, which can remove cytoplasmic contents and it is associated with various diseases. More and more studies have shown that mitophagy may be related to the occurrence and development of carcinoma of Cervix Uteri. This article reviews the study progress on the role of mitophagy in the occurrence and development of cervical carcinoma.