Green Syn Thesis and Biological Applications of Cerium Oxide Nanoparticles

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Justin M. Farook, Shushant I. Jigan, Challaraj Emmanuel E. S., Chandrakala Linganna, Sanjay Rathod, Jai Shanker Pillai H. P.


In the biological and medical sciences, CeO2 nanoparticles (NPs) have demonstrated great potential as therapeutic agents. In the final interactions of the NP with target cells, the physicochemical characteristics of CeO2-NPs, such as size, aggregation status in liquid, and surface charge, are crucial. Recently, CeO2-NPs have been produced using a variety of bio-directed approaches using natural and organic matrices as stabilising agents in order to create biocompatible CeO2-NPs, resolving safety concerns and creating the ideal environment for their successful application in biomedicine. The several green methods for creating CeO2-NPs are covered in this review along with their benefits and difficulties. This review also emphasises current developments in the possible usage of CeO-NPs, which have superior redox characteristics in comparison to bulk materials. Additionally, the existence of a mixed valance state is crucial.

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