Jundishapur Journal of Microbiology

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Prevalence of Toxoplasma gondii Infection in Healthy Volunteer Blood Donors Using Serological and Molecular Methods from Chaharmahal and Bakhtiari Province, Southwest Iran

Kourosh Manouchehri Naeini ORCID 1 , Ehsan Heidari Soureshjani ORCID 2 , 3 , Mahnaz Jafari ORCID 1 , Shahrbanou Parchami ORCID 4 , Gharib Karimi ORCID 2 and Rahman Abdizadeh ORCID 1 , *
Authors Information
1 Department of Medical Parasitology and Mycology, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
3 Shahrekord Regional Blood Transfusion Center, Shahrekord, Iran
4 Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
Article information
  • Jundishapur Journal of Microbiology: May 31, 2019, 12 (5); e91042
  • Published Online: May 21, 2019
  • Article Type: Research Article
  • Received: February 26, 2019
  • Revised: May 4, 2019
  • Accepted: May 6, 2019
  • DOI: 10.5812/jjm.91042

To Cite: Manouchehri Naeini K, Heidari Soureshjani E, Jafari M, Parchami S, Karimi G, et al. Prevalence of Toxoplasma gondii Infection in Healthy Volunteer Blood Donors Using Serological and Molecular Methods from Chaharmahal and Bakhtiari Province, Southwest Iran, Jundishapur J Microbiol. 2019 ; 12(5):e91042. doi: 10.5812/jjm.91042.

Abstract
Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Rahimi MT, Daryani A, Sarvi S, Shokri A, Ahmadpour E, Teshnizi SH, et al. Cats and Toxoplasma gondii: A systematic review and meta-analysis in Iran. Onderstepoort J Vet Res. 2015;82(1):e1-e10. doi: 10.4102/ojvr.v82i1.823. [PubMed: 26017063]. [PubMed Central: PMC6238687].
  • 2. Dubey JP. Toxoplasmosis-a waterborne zoonosis. Vet Parasitol. 2004;126(1-2):57-72. doi: 10.1016/j.vetpar.2004.09.005. [PubMed: 15567579].
  • 3. Belluco S, Mancin M, Conficoni D, Simonato G, Pietrobelli M, Ricci A. Investigating the determinants of Toxoplasma gondii prevalence in meat: A systematic review and meta-regression. PLoS One. 2016;11(4). e0153856. doi: 10.1371/journal.pone.0153856. [PubMed: 27082633]. [PubMed Central: PMC4833317].
  • 4. Tenter AM, Heckeroth AR, Weiss LM. Toxoplasma gondii: From animals to humans. Int J Parasitol. 2000;30(12-13):1217-58. doi: 10.1016/S0020-7519(00)00124-7. [PubMed: 11113252]. [PubMed Central: PMC3109627].
  • 5. Dubey JP, Jones JL. Toxoplasma gondii infection in humans and animals in the United States. Int J Parasitol. 2008;38(11):1257-78. doi: 10.1016/j.ijpara.2008.03.007. [PubMed: 18508057].
  • 6. Sarkari B, Shafiei R, Zare M, Sohrabpour S, Kasraian L. Seroprevalence and molecular diagnosis of Toxoplasma gondii infection among blood donors in southern Iran. J Infect Dev Ctries. 2014;8(4):543-7. doi: 10.3855/jidc.3831. [PubMed: 24727522].
  • 7. Slavin MA, Meyers JD, Remington JS, Hackman RC. Toxoplasma gondii infection in marrow transplant recipients: A 20 year experience. Bone Marrow Transplant. 1994;13(5):549-57. [PubMed: 8054907].
  • 8. Foroutan-Rad M, Majidiani H, Dalvand S, Daryani A, Kooti W, Saki J, et al. Toxoplasmosis in blood donors: A systematic review and meta-analysis. Transfus Med Rev. 2016;30(3):116-22. doi: 10.1016/j.tmrv.2016.03.002. [PubMed: 27145927].
  • 9. Daryani A, Sarvi S, Aarabi M, Mizani A, Ahmadpour E, Shokri A, et al. Seroprevalence of Toxoplasma gondii in the Iranian general population: A systematic review and meta-analysis. Acta Trop. 2014;137:185-94. doi: 10.1016/j.actatropica.2014.05.015. [PubMed: 24887263].
  • 10. Bhopale GM. Pathogenesis of toxoplasmosis. Comp Immunol Microbiol Infect Dis. 2003;26(4):213-22. doi: 10.1016/S0147-9571(02)00058-9. [PubMed: 12676122].
  • 11. Machala L, Kodym P, Maly M, Geleneky M, Beran O, Jilich D. [Toxoplasmosis in immunocompromised patients]. Epidemiol Mikrobiol Imunol. 2015;64(2):59-65. Czech. [PubMed: 26099608].
  • 12. Wang ZD, Liu HH, Ma ZX, Ma HY, Li ZY, Yang ZB, et al. Toxoplasma gondii infection in immunocompromised patients: A systematic review and meta-analysis. Front Microbiol. 2017;8:389. doi: 10.3389/fmicb.2017.00389. [PubMed: 28337191]. [PubMed Central: PMC5343064].
  • 13. Mele A, Paterson PJ, Prentice HG, Leoni P, Kibbler CC. Toxoplasmosis in bone marrow transplantation: A report of two cases and systematic review of the literature. Bone Marrow Transplant. 2002;29(8):691-8. doi: 10.1038/sj.bmt.1703425. [PubMed: 12180115].
  • 14. Wendel Neto S. Current concepts on the transmission of bacteria and parasites by blood components. Sao Paulo Med J. 1995;113(6):1036-52. doi: 10.1590/S1516-31801995000600007. [PubMed: 8731290].
  • 15. Siegel SE, Lunde MN, Gelderman AH, Halterman RH, Brown JA, Levine AS, et al. Transmission of toxoplasmosis by leukocyte transfusion. Blood. 1971;37(4):388-94. [PubMed: 4927414].
  • 16. Karimi G, Mardani A, Zadsar M. Prevalence of Toxoplasma gondii among Iranian blood donors: A narrative review article. Iran J Parasitol. 2016;11(1):10-8. [PubMed: 27095963]. [PubMed Central: PMC4835458].
  • 17. Saki J, Foroutan M, Khodkar I, Khodadadi A, Nazari L. Seroprevalence and molecular detection of Toxoplasma gondii in healthy blood donors in southwest Iran. Transfus Apher Sci. 2019;58(1):79-82. doi: 10.1016/j.transci.2018.12.003. [PubMed: 30579749].
  • 18. Zainodini N, Zare-Bidaki M, Abdollahi SH, Afrooz M, Ziaali N, Ebrahimian M, et al. Molecular and serological detection of acute and latent toxoplasmosis using real-time PCR and ELISA techniques in blood donors of Rafsanjan city, Iran, 2013. Iran J Parasitol. 2014;9(3):336-41. [PubMed: 25678917]. [PubMed Central: PMC4316564].
  • 19. Elsheikha HM, Azab MS, Abousamra NK, Rahbar MH, Elghannam DM, Raafat D. Seroprevalence of and risk factors for Toxoplasma gondii antibodies among asymptomatic blood donors in Egypt. Parasitol Res. 2009;104(6):1471-6. doi: 10.1007/s00436-009-1350-z. [PubMed: 19198880].
  • 20. Gholami M, Maghsod AH, Mohammadi A, Fallah N, Fallah M. [Seroprevalence of Toxoplasmosis in blood donors of Hamadan transfusion Center in 2013]. Yafte. 2015;17(2). Persian.
  • 21. Bahhaj R, Ahmadpour E, Mahami-Oskouei M, Fallah E, Shamsasenjan K, Safaiyan A. Toxoplasma gondii infection and related risk factors among blood donors in northwest Iran. Arch Clin Infect Dis. 2017;12(2). e62005. doi: 10.5812/archcid.62005.
  • 22. Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, et al. Loop-mediated isothermal amplification of DNA. Nucleic Acids Res. 2000;28(12). E63. doi: 10.1093/nar/28.12.e63. [PubMed: 10871386]. [PubMed Central: PMC102748].
  • 23. Lin Z, Zhang Y, Zhang H, Zhou Y, Cao J, Zhou J. Comparison of loop-mediated isothermal amplification (LAMP) and real-time PCR method targeting a 529-bp repeat element for diagnosis of toxoplasmosis. Vet Parasitol. 2012;185(2-4):296-300. doi: 10.1016/j.vetpar.2011.10.016. [PubMed: 22051073].
  • 24. Fallahi S, Seyyed Tabaei SJ, Pournia Y, Zebardast N, Kazemi B. Comparison of loop-mediated isothermal amplification (LAMP) and nested-PCR assay targeting the RE and B1 gene for detection of Toxoplasma gondii in blood samples of children with leukaemia. Diagn Microbiol Infect Dis. 2014;79(3):347-54. doi: 10.1016/j.diagmicrobio.2014.02.014. [PubMed: 24792838].
  • 25. Rezaei F, Sarvi S, Sharif M, Hejazi SH, Pagheh AS, Aghayan SA, et al. A systematic review of Toxoplasma gondii antigens to find the best vaccine candidates for immunization. Microb Pathog. 2019;126:172-84. doi: 10.1016/j.micpath.2018.11.003. [PubMed: 30399440].
  • 26. Ferdowsi S, Farsi L, Tajalli S, Soltani H. Seroprevalence anti-Toxoplasma gondii antibodies and anti-epstein-barr virus (ebv) antibody among volunteer blood donors referred Gonabad Blood Transfusion Organization. J Zabol Univ Med Sci Health Serv. 2013;5(2):60-9.
  • 27. Jafari Modrek M, Mousavi M, Saravani R. Toxoplasma gondii Seroprevalence among blood donors in Zahedan, Southeastern Iran. Int J Infect. 2014;1(2). doi: 10.17795/iji-21111.
  • 28. Zarean M, Shafiei R, Gholami M, Fata A, Rahmati Balaghaleh M, Kariminik A, et al. seroprevalence of anti-Toxoplasma gondii antibodies in healthy voluntary blood donors from Mashhad City, Iran. Arch Iran Med. 2017;20(7):441-5. [PubMed: 28745905].
  • 29. Tappeh KH, Musavi J, Safa MB, Galavani H, Alizadeh H. Prevalence of IgG and IgM anti-Toxoplasma gondii Antibodies in blood donors at Urmia Blood Transfusion Organization, Iran. Turkiye Parazitol Derg. 2017;41(1):1-4. doi: 10.5152/tpd.2017.5066. [PubMed: 28483726].
  • 30. Mahmoudvand H, Saedi Dezaki E, Soleimani S, Baneshi MR, Kheirandish F, Ezatpour B, et al. Seroprevalence and risk factors of Toxoplasma gondii infection among healthy blood donors in south-east of Iran. Parasite Immunol. 2015;37(7):362-7. doi: 10.1111/pim.12198. [PubMed: 25891186].
  • 31. Coelho RA, Kobayashi M, Carvalho LB Jr. Prevalence of IgG antibodies specific to Toxoplasma gondii among blood donors in Recife, Northeast Brazil. Rev Inst Med Trop Sao Paulo. 2003;45(4):229-31. doi: 10.1590/S0036-46652003000400011. [PubMed: 14502353].
  • 32. Walle F, Kebede N, Tsegaye A, Kassa T. Seroprevalence and risk factors for Toxoplasmosis in HIV infected and non-infected individuals in Bahir Dar, Northwest Ethiopia. Parasit Vectors. 2013;6(1):15. doi: 10.1186/1756-3305-6-15. [PubMed: 23324409]. [PubMed Central: PMC3556116].
  • 33. van der Colf BE, Noden BH, Wilkinson R, Chipare I. Low seroprevalence of antibodies to Toxoplasma gondii in blood donors in central Namibia. Southern Afr J Infect Dis. 2015;29(3):101-4. doi: 10.1080/23120053.2014.11441579.
  • 34. Sundar P, Mahadevan A, Jayshree RS, Subbakrishna DK, Shankar SK. Toxoplasma seroprevalence in healthy voluntary blood donors from urban Karnataka. Indian J Med Res. 2007;126(1):50-5. [PubMed: 17890824].
  • 35. Ormazdi H, Razmju E, Memar A, Akhlaghi L, Hadighi R, Sanikhani N. Investigation of antibodies (IgG and IgM) against Toxoplasma gondii in blood donors referred to Tehran Blood Transfusion Organization by ELISA. J Urmia Univ Med Sci. 2010;21(2):212-6.
  • 36. Mansouri A, Adhami Mojarad MR, Badfar G, Abasian L, Rahmati S, Kooti W, et al. Epidemiology of Toxoplasma gondii among blood donors in Iran: A systematic review and meta-analysis. Transfus Apher Sci. 2017;56(3):404-9. doi: 10.1016/j.transci.2017.03.011. [PubMed: 28433405].
  • 37. Shaapan RM, Abd El Wah WM, Abd El Haf MED, Elfadaly HA, Ahmed Hamd D. Toxoplasma gondii infection and associated sociodemographic and behavioral risk factors among blood donors. Asian J Epidemiol. 2018;11(2):52-8. doi: 10.3923/aje.2018.52.58.
  • 38. Shaddel M, Mirzaii-Dizgah I, Hoshangi M. Anti-Toxoplasma gondii antibody levels in blood supply of Shiraz Blood Transfusion Institute, Iran. Iran J Parasitol. 2014;9(1):120-4. [PubMed: 25642268]. [PubMed Central: PMC4289869].
  • 39. Zhang H, Thekisoe OM, Aboge GO, Kyan H, Yamagishi J, Inoue N, et al. Toxoplasma gondii: Sensitive and rapid detection of infection by loop-mediated isothermal amplification (LAMP) method. Exp Parasitol. 2009;122(1):47-50. doi: 10.1016/j.exppara.2009.01.012. [PubMed: 19545521].
  • 40. Liesenfeld O, Press C, Montoya JG, Gill R, Isaac-Renton JL, Hedman K, et al. False-positive results in immunoglobulin M (IgM) toxoplasma antibody tests and importance of confirmatory testing: The Platelia Toxo IgM test. J Clin Microbiol. 1997;35(1):174-8. [PubMed: 8968902]. [PubMed Central: PMC229533].
  • 41. Sadooghian S, Mahmoudvand H, Mohammadi MA, Nazari Sarcheshmeh N, Tavakoli Kareshk A, Kamiabi H, et al. Prevalence of Toxoplasma gondii infection among healthy blood donors in northeast of Iran. Iran J Parasitol. 2017;12(4):554-62. [PubMed: 29317880]. [PubMed Central: PMC5756305].
  • 42. Moshfe A, Arefkhah N, Sarkari B, Kazemi S, Mardani A. Toxoplasma gondii in blood donors: A study in boyer-ahmad county, southwest Iran. Interdiscip Perspect Infect Dis. 2018;2018:3813612. doi: 10.1155/2018/3813612. [PubMed: 29849610]. [PubMed Central: PMC5925030].
  • 43. Sun XM, Ji YS, Liu XY, Xiang M, He G, Xie L, et al. Improvement and evaluation of loop-mediated isothermal amplification for rapid detection of Toxoplasma gondii infection in human blood samples. PLoS One. 2017;12(1). e0169125. doi: 10.1371/journal.pone.0169125. [PubMed: 28056092]. [PubMed Central: PMC5215908].

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