Jundishapur Journal of Microbiology

Published by: Kowsar

Investigating Chlamydia trachomatis and Genital Mycoplasma Prevalence and Apoptosis Markers in Infertile and Fertile Couples

Mojtaba Moosavian 1 , 2 , Ataallah Ghadiri 3 , 4 , Sareh Amirzadeh 5 , Mohammad Rashno 2 , 3 , Maryam Afzali 1 and Khadijeh Ahmadi 1 , *
Authors Information
1 Infectious and Tropical Diseases Research Center, Health Research Institue, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Department of Microbiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3 Department of Immunology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
4 Cell and Molecular Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
5 Infertility Research and Treatment Center of ACER, Ahvaz, Iran
Article information
  • Jundishapur Journal of Microbiology: January 31, 2019, 12 (1); e84954
  • Published Online: January 13, 2019
  • Article Type: Research Article
  • Received: October 4, 2018
  • Revised: December 31, 2018
  • Accepted: January 1, 2019
  • DOI: 10.5812/jjm.84954

To Cite: Moosavian M, Ghadiri A, Amirzadeh S, Rashno M, Afzali M, et al. Investigating Chlamydia trachomatis and Genital Mycoplasma Prevalence and Apoptosis Markers in Infertile and Fertile Couples, Jundishapur J Microbiol. 2019 ; 12(1):e84954. doi: 10.5812/jjm.84954.

Abstract
Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Footnotes
References
  • 1. Ouzounova-Raykova V, Ouzounova I, Mitov I. Chlamydia trachomatis infection as a problem among male partners of infertile couples. Andrologia. 2009;41(1):14-9. doi: 10.1111/j.1439-0272.2008.00881.x. [PubMed: 19143724].
  • 2. Michou IV, Constantoulakis P, Makarounis K, Georgoulias G, Kapetanios V, Tsilivakos V. Molecular investigation of menstrual tissue for the presence of Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis collected by women with a history of infertility. J Obstet Gynaecol Res. 2014;40(1):237-42. doi: 10.1111/jog.12165. [PubMed: 24118383].
  • 3. Lee JS, Kim KT, Lee HS, Yang KM, Seo JT, Choe JH. Concordance of Ureaplasma urealyticum and Mycoplasma hominis in infertile couples: Impact on semen parameters. Urology. 2013;81(6):1219-24. doi: 10.1016/j.urology.2013.02.044. [PubMed: 23602797].
  • 4. Liu J, Wang Q, Ji X, Guo S, Dai Y, Zhang Z, et al. Prevalence of Ureaplasma urealyticum, Mycoplasma hominis, Chlamydia trachomatis infections, and semen quality in infertile and fertile men in China. Urology. 2014;83(4):795-9. doi: 10.1016/j.urology.2013.11.009. [PubMed: 24411218].
  • 5. Sellami H, Znazen A, Sellami A, Mnif H, Louati N, Ben Zarrouk S, et al. Molecular detection of Chlamydia trachomatis and other sexually transmitted bacteria in semen of male partners of infertile couples in Tunisia: The effect on semen parameters and spermatozoa apoptosis markers. PLoS One. 2014;9(7). e98903. doi: 10.1371/journal.pone.0098903. [PubMed: 25019616]. [PubMed Central: PMC4096407].
  • 6. Word Health Organisation. WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. Cambridge University Press; 1999.
  • 7. Golshani M, Eslami G, Ghobadloo SM, Fallah F, Goudarzi H, Rahbar AS, et al. Detection of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum by multiplex PCR in semen sample of infertile men. Iran J Public Health. 2007;36(2):50-7.
  • 8. Schlicht MJ, Lovrich SD, Sartin JS, Karpinsky P, Callister SM, Agger WA. High prevalence of genital mycoplasmas among sexually active young adults with urethritis or cervicitis symptoms in La Crosse, Wisconsin. J Clin Microbiol. 2004;42(10):4636-40. doi: 10.1128/JCM.42.10.4636-4640.2004. [PubMed: 15472322]. [PubMed Central: PMC522307].
  • 9. Abou Tayoun AN, Burchard PR, Caliendo AM, Scherer A, Tsongalis GJ. A multiplex PCR assay for the simultaneous detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis. Exp Mol Pathol. 2015;98(2):214-8. doi: 10.1016/j.yexmp.2015.01.011. [PubMed: 25595915].
  • 10. Takeda K, Uchiyama K, Kinukawa M, Tagami T, Kaneda M, Watanabe S. Evaluation of sperm DNA damage in bulls by TUNEL assay as a parameter of semen quality. J Reprod Dev. 2015;61(3):185-90. doi: 10.1262/jrd.2014-140. [PubMed: 25739957]. [PubMed Central: PMC4498374].
  • 11. Wang X, Sharma RK, Sikka SC, Thomas AJ Jr, Falcone T, Agarwal A. Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility. Fertil Steril. 2003;80(3):531-5. [PubMed: 12969693].
  • 12. La Vignera S, Vicari E, Condorelli RA, D'Agata R, Calogero AE. Male accessory gland infection and sperm parameters (review). Int J Androl. 2011;34(5 Pt 2):e330-47. doi: 10.1111/j.1365-2605.2011.01200.x. [PubMed: 21696400].
  • 13. Potts JM, Sharma R, Pasqualotto F, Nelson D, Hall G, Agarwal A. Association of ureaplasma urealyticum with abnormal reactive oxygen species levels and absence of leukocytospermia. J Urol. 2000;163(6):1775-8. [PubMed: 10799180].
  • 14. Joki-Korpela P, Sahrakorpi N, Halttunen M, Surcel HM, Paavonen J, Tiitinen A. The role of Chlamydia trachomatis infection in male infertility. Fertil Steril. 2009;91(4 Suppl):1448-50. doi: 10.1016/j.fertnstert.2008.06.051. [PubMed: 18706556].
  • 15. Badami N, Salari MH. Rate of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in infertile females and control group. Iran J Public Health. 2001;30(1-2):57-60.
  • 16. Al-Sweih NA, Al-Fadli AH, Omu AE, Rotimi VO. Prevalence of Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, and Ureaplasma urealyticum infections and seminal quality in infertile and fertile men in Kuwait. J Androl. 2012;33(6):1323-9. doi: 10.2164/jandrol.111.013821. [PubMed: 22052774].
  • 17. Gunyeli I, Abike F, Dunder I, Aslan C, Tapisiz OL, Temizkan O, et al. Chlamydia, Mycoplasma and Ureaplasma infections in infertile couples and effects of these infections on fertility. Arch Gynecol Obstet. 2011;283(2):379-85. doi: 10.1007/s00404-010-1726-4. [PubMed: 20978774].
  • 18. Peerayeh S, Samimi R. Comparison of culture with the polymerase chain reaction for detection of gennital mycoplasma. Eur J Gen Med. 2008;5(2):107-11. doi: 10.29333/ejgm/82587.
  • 19. Stellrecht KA, Woron AM, Mishrik NG, Venezia RA. Comparison of multiplex PCR assay with culture for detection of genital mycoplasmas. J Clin Microbiol. 2004;42(4):1528-33. [PubMed: 15070999]. [PubMed Central: PMC387538].
  • 20. Gdoura R, Keskes-Ammar L, Bouzid F, Eb F, Hammami A, Orfila J. Chlamydia trachomatis and male infertility in Tunisia. Eur J Contracept Reprod Health Care. 2001;6(2):102-7. [PubMed: 11518447].
  • 21. Fraczek M, Kurpisz M. Mechanisms of the harmful effects of bacterial semen infection on ejaculated human spermatozoa: Potential inflammatory markers in semen. Folia Histochem Cytobiol. 2015;53(3):201-17. doi: 10.5603/fhc.a2015.0019. [PubMed: 26306512].
  • 22. Taylor SL, Weng SL, Fox P, Duran EH, Morshedi MS, Oehninger S, et al. Somatic cell apoptosis markers and pathways in human ejaculated sperm: Potential utility as indicators of sperm quality. Mol Hum Reprod. 2004;10(11):825-34. doi: 10.1093/molehr/gah099. [PubMed: 15465851].
  • 23. Satta A, Stivala A, Garozzo A, Morello A, Perdichizzi A, Vicari E, et al. Experimental Chlamydia trachomatis infection causes apoptosis in human sperm. Hum Reprod. 2006;21(1):134-7. doi: 10.1093/humrep/dei269. [PubMed: 16126752].
  • 24. Eley A, Hosseinzadeh S, Hakimi H, Geary I, Pacey AA. Apoptosis of ejaculated human sperm is induced by co-incubation with Chlamydia trachomatis lipopolysaccharide. Hum Reprod. 2005;20(9):2601-7. doi: 10.1093/humrep/dei082. [PubMed: 15905291].

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