Jundishapur Journal of Microbiology

Published by: Kowsar

Distribution of Virulence and Antimicrobial Resistance Genes in Phylogenetic Groups of Escherichia coli Strains Isolated from Mexican Patients with Urinary Infection

Juan Carlos Bravata-Alcantara 1 , Juan Manuel Bello-Lopez 2 , Iliana Alejandra Cortes-Ortiz 3 , Juan Jose Mendez-Velazquez 4 , Brandon Aviles-Soto 5 , Laura Itzel Quintas-Granados 6 , Sonia del Carmen Chavez-Ocaña 1 , Cecilia Rosel-Pech 7 , Juan Antonio Gonzalez-Barrios 8 and Monica Sierra Martinez 1 , *
Authors Information
1 Genetics and Molecular Diagnosis Laboratory, Juárez de Mexico Hospital, Mexico City, Mexico
2 Research Unit in Microbiology and Toxicology, Juárez de Mexico Hospital, Mexico City, Mexico
3 Bacteriology Laboratory, Juárez de Mexico Hospital, Mexico City, Mexico
4 Zaragoza School of Higher Studies, National Autonomous University of Mexico, Mexico City, Mexico
5 Technological University of Tecámac, Tecámac, Mexico
6 Mexiquense del Bicentenario University, Higher Studies Unit of Tultitlán, Mexico City, Mexico
7 Medical Research Unit in Immunology and Infectious Diseases, Hospital of Infectology Daniel Méndez Hernández, la Raza National Medical Center, Mexico City, Mexico
8 Laboratory of Genomic Medicine, Regional Hospital, ISSSTE, Mexico City, Mexico
Article information
  • Jundishapur Journal of Microbiology: March 31, 2019, 12 (3); e83711
  • Published Online: February 27, 2019
  • Article Type: Research Article
  • Received: August 29, 2018
  • Revised: January 9, 2019
  • Accepted: January 16, 2019
  • DOI: 10.5812/jjm.83711

To Cite: Bravata-Alcantara J C , Bello-Lopez J M, Cortes-Ortiz I A, Mendez-Velazquez J J, Aviles-Soto B, et al. Distribution of Virulence and Antimicrobial Resistance Genes in Phylogenetic Groups of Escherichia coli Strains Isolated from Mexican Patients with Urinary Infection, Jundishapur J Microbiol. 2019 ; 12(3):e83711. doi: 10.5812/jjm.83711.

Abstract
Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Footnotes
References
  • 1. Herzer PJ, Inouye S, Inouye M, Whittam TS. Phylogenetic distribution of branched RNA-linked multicopy single-stranded DNA among natural isolates of Escherichia coli. J Bacteriol. 1990;172(11):6175-81. [PubMed: 1699928]. [PubMed Central: PMC526797].
  • 2. Flores-Mireles AL, Walker JN, Caparon M, Hultgren SJ. Urinary tract infections: Epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015;13(5):269-84. doi: 10.1038/nrmicro3432. [PubMed: 25853778]. [PubMed Central: PMC4457377].
  • 3. Kostakioti M, Hultgren SJ, Hadjifrangiskou M. Molecular blueprint of uropathogenic Escherichia coli virulence provides clues toward the development of anti-virulence therapeutics. Virulence. 2012;3(7):592-4. doi: 10.4161/viru.22364. [PubMed: 23154288]. [PubMed Central: PMC3545937].
  • 4. Sistema Nacional de Vigilancia Epidemiológica (SINAVE). Anuarios de Morbilidad: Infecciones de vías urinarias. 2016. Available from: http://www.epidemiologia.salud.gob.mx/anuario/20160/incidencia/incidencia_casos_nuevos_enfermedad_grupo_edad.pdf.
  • 5. Bjorkman I, Berg J, Viberg N, Stalsby Lundborg C. Awareness of antibiotic resistance and antibiotic prescribing in UTI treatment: A qualitative study among primary care physicians in Sweden. Scand J Prim Health Care. 2013;31(1):50-5. doi: 10.3109/02813432.2012.751695. [PubMed: 23281925]. [PubMed Central: PMC3587295].
  • 6. Vranic SM, Zatric N, Rebic V, Aljicevic M, Abdulzaimovic A. The most frequent isolates from outpatients with urinary tract infection. Mater Sociomed. 2017;29(1):17-20. doi: 10.5455/msm.2017.29.17-20. [PubMed: 28484348]. [PubMed Central: PMC5402357].
  • 7. Chabros L, Mlynarczyk G, Sawicka-Grzelak A, Swoboda-Kopec E, Kuthan R, de Walthoffen SW, et al. Comparison of bacteria isolated from urinary tract infections in patients on transplant versus urologic wards. Transplant Proc. 2011;43(8):3125-7. doi: 10.1016/j.transproceed.2011.09.004. [PubMed: 21996243].
  • 8. Momtaz H, Karimian A, Madani M, Safarpoor Dehkordi F, Ranjbar R, Sarshar M, et al. Uropathogenic Escherichia coli in Iran: Serogroup distributions, virulence factors and antimicrobial resistance properties. Ann Clin Microbiol Antimicrob. 2013;12:8. doi: 10.1186/1476-0711-12-8. [PubMed: 23627669]. [PubMed Central: PMC3651382].
  • 9. Nielubowicz GR, Mobley HL. Host-pathogen interactions in urinary tract infection. Nat Rev Urol. 2010;7(8):430-41. doi: 10.1038/nrurol.2010.101. [PubMed: 20647992].
  • 10. Wright KJ, Hultgren SJ. Sticky fibers and uropathogenesis: Bacterial adhesins in the urinary tract. Future Microbiol. 2006;1(1):75-87. doi: 10.2217/17460913.1.1.75. [PubMed: 17661687].
  • 11. Hemmatinezhad B, Khamesipour F, Mohammadi M, Safarpoor Dehkordi F, Mashak Z. Microbiological investigation of o-serogroups, virulence factors and antimicrobial resistance properties of shiga toxin-producing escherichia coliisolated from ostrich, turkey and quail meats. J Food Saf. 2015;35(4):491-500. doi: 10.1111/jfs.12199.
  • 12. Ranjbar R, Safarpoor Dehkordi F, Sakhaei Shahreza MH, Rahimi E. Prevalence, identification of virulence factors, O-serogroups and antibiotic resistance properties of Shiga-toxin producing Escherichia coli strains isolated from raw milk and traditional dairy products. Antimicrob Resist Infect Control. 2018;7:53. doi: 10.1186/s13756-018-0345-x. [PubMed: 29686859]. [PubMed Central: PMC5902837].
  • 13. Momtaz H, Dehkordi FS, Hosseini MJ, Sarshar M, Heidari M. Serogroups, virulence genes and antibiotic resistance in Shiga toxin-producing Escherichia coli isolated from diarrheic and non-diarrheic pediatric patients in Iran. Gut Pathog. 2013;5(1):39. doi: 10.1186/1757-4749-5-39. [PubMed: 24330673]. [PubMed Central: PMC3866933].
  • 14. Dehkordi FS, Yazdani F, Mozafari J, Valizadeh Y. Virulence factors, serogroups and antimicrobial resistance properties of Escherichia coli strains in fermented dairy products. BMC Res Notes. 2014;7:217. doi: 10.1186/1756-0500-7-217. [PubMed: 24708594]. [PubMed Central: PMC3983858].
  • 15. Dormanesh B, Safarpoor Dehkordi F, Hosseini S, Momtaz H, Mirnejad R, Hoseini MJ, et al. Virulence factors and o-serogroups profiles of uropathogenic Escherichia coli isolated from Iranian pediatric patients. Iran Red Crescent Med J. 2014;16(2). e14627. doi: 10.5812/ircmj.14627. [PubMed: 24719745]. [PubMed Central: PMC3965878].
  • 16. Shahrani M, Dehkordi FS, Momtaz H. Characterization of Escherichia coli virulence genes, pathotypes and antibiotic resistance properties in diarrheic calves in Iran. Biol Res. 2014;47:28. doi: 10.1186/0717-6287-47-28. [PubMed: 25052999]. [PubMed Central: PMC4105491].
  • 17. Ranjbar R, Masoudimanesh M, Dehkordi FS, Jonaidi-Jafari N, Rahimi E. Shiga (Vero)-toxin producing Escherichia coli isolated from the hospital foods; virulence factors, o-serogroups and antimicrobial resistance properties. Antimicrob Resist Infect Control. 2017;6:4. doi: 10.1186/s13756-016-0163-y. [PubMed: 28074125]. [PubMed Central: PMC5219770].
  • 18. Nagamatsu K, Hannan TJ, Guest RL, Kostakioti M, Hadjifrangiskou M, Binkley J, et al. Dysregulation of Escherichia coli alpha-hemolysin expression alters the course of acute and persistent urinary tract infection. Proc Natl Acad Sci U S A. 2015;112(8):E871-80. doi: 10.1073/pnas.1500374112. [PubMed: 25675528]. [PubMed Central: PMC4345586].
  • 19. Guiton PS, Cusumano CK, Kline KA, Dodson KW, Han Z, Janetka JW, et al. Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob Agents Chemother. 2012;56(9):4738-45. doi: 10.1128/AAC.00447-12. [PubMed: 22733070]. [PubMed Central: PMC3421856].
  • 20. Rippere-Lampe KE, O'Brien AD, Conran R, Lockman HA. Mutation of the gene encoding cytotoxic necrotizing factor type 1 (cnf(1)) attenuates the virulence of uropathogenic Escherichia coli. Infect Immun. 2001;69(6):3954-64. doi: 10.1128/IAI.69.6.3954-3964.2001. [PubMed: 11349064]. [PubMed Central: PMC98434].
  • 21. Koshesh M, Mansouri S, Hashemizadeh Z, Kalantar-Neyestanaki D. Identification of extended-spectrum β-lactamase genes and ampc-β-lactamase in clinical isolates of escherichia coli recovered from patients with urinary tract infections in Kerman, Iran. Arch Pediatr Infect Dis. 2016;5(2). e37968. doi: 10.5812/pedinfect.37968.
  • 22. Woodford N, Ward ME, Kaufmann ME, Turton J, Fagan EJ, James D, et al. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. J Antimicrob Chemother. 2004;54(4):735-43. doi: 10.1093/jac/dkh424. [PubMed: 15347638].
  • 23. Clermont O, Bonacorsi S, Bingen E. Rapid and simple determination of the Escherichia coli phylogenetic group. Appl Environ Microbiol. 2000;66(10):4555-8. doi: 10.1128/AEM.66.10.4555-4558.2000. [PubMed: 11010916]. [PubMed Central: PMC92342].
  • 24. Clermont O, Christenson JK, Denamur E, Gordon DM. The clermont Escherichia coli phylo-typing method revisited: Improvement of specificity and detection of new phylo-groups. Environ Microbiol Rep. 2013;5(1):58-65. doi: 10.1111/1758-2229.12019. [PubMed: 23757131].
  • 25. Qu W, Zhou Y, Zhang Y, Lu Y, Wang X, Zhao D, et al. MFEprimer-2.0: A fast thermodynamics-based program for checking PCR primer specificity. Nucleic Acids Res. 2012;40(Web Server issue):W205-8. doi: 10.1093/nar/gks552. [PubMed: 22689644]. [PubMed Central: PMC3394324].
  • 26. Tartof SY, Solberg OD, Riley LW. Genotypic analyses of uropathogenic Escherichia coli based on fimH single nucleotide polymorphisms (SNPs). J Med Microbiol. 2007;56(Pt 10):1363-9. doi: 10.1099/jmm.0.47262-0. [PubMed: 17893175].
  • 27. Johnson JR, Stell AL. Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. J Infect Dis. 2000;181(1):261-72. doi: 10.1086/315217. [PubMed: 10608775].
  • 28. Magoue CL, Melin P, Gangoue-Pieboji J, Okomo Assoumou MC, Boreux R, De Mol P. Prevalence and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae in Ngaoundere, Cameroon. Clin Microbiol Infect. 2013;19(9):E416-20. doi: 10.1111/1469-0691.12239. [PubMed: 23647948].
  • 29. Hassan SA, Shobrak MY. Detection of genes mediating beta-lactamase production in isolates of enterobacteria recovered from wild pets in Saudi Arabia. Vet World. 2015;8(12):1400-4. doi: 10.14202/vetworld.2015.1400-1404. [PubMed: 27047051]. [PubMed Central: PMC4774817].
  • 30. Kim J, Jeon S, Rhie H. Rapid detection of extended spectrum β-lactamase (ESBL) for Enterobacteriaceae by use of a multiplex PCR-based method. Infect Chemother. 2009;41(3):181-4. doi: 10.3947/ic.2009.41.3.181.
  • 31. Foxman B. The epidemiology of urinary tract infection. Nat Rev Urol. 2010;7(12):653-60. doi: 10.1038/nrurol.2010.190. [PubMed: 21139641].
  • 32. Stamm WE. Scientific and clinical challenges in the management of urinary tract infections. Am J Med. 2002;113 Suppl 1A:1S-4S. doi: 10.1016/S0002-9343(02)01053-7. [PubMed: 12113865].
  • 33. Neamati F, Firoozeh F, Saffari M, Zibaei M. Virulence genes and antimicrobial resistance pattern in uropathogenic Escherichia coli isolated from hospitalized patients in Kashan, Iran. Jundishapur J Microbiol. 2015;8(2). e17514. doi: 10.5812/jjm.17514. [PubMed: 25825647]. [PubMed Central: PMC4376973].
  • 34. Orsi RH, Stoppe NC, Sato MI, Ottoboni LM. Identification of Escherichia coli from groups A, B1, B2 and D in drinking water in Brazil. J Water Health. 2007;5(2):323-7. doi: 10.2166/wh.2007.028. [PubMed: 17674580].
  • 35. Boyd EF, Hartl DL. Chromosomal regions specific to pathogenic isolates of Escherichia coli have a phylogenetically clustered distribution. J Bacteriol. 1998;180(5):1159-65. [PubMed: 9495754]. [PubMed Central: PMC107003].
  • 36. Bingen E, Picard B, Brahimi N, Mathy S, Desjardins P, Elion J, et al. Phylogenetic analysis of Escherichia coli strains causing neonatal meningitis suggests horizontal gene transfer from a predominant pool of highly virulent B2 group strains. J Infect Dis. 1998;177(3):642-50. doi: 10.1086/514217. [PubMed: 9498443].
  • 37. Bouckaert J, Berglund J, Schembri M, De Genst E, Cools L, Wuhrer M, et al. Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Mol Microbiol. 2005;55(2):441-55. doi: 10.1111/j.1365-2958.2004.04415.x. [PubMed: 15659162].
  • 38. Marklund BI, Tennent JM, Garcia E, Hamers A, Baga M, Lindberg F, et al. Horizontal gene transfer of the Escherichia coli pap and prs pili operons as a mechanism for the development of tissue-specific adhesive properties. Mol Microbiol. 1992;6(16):2225-42. doi: 10.1111/j.1365-2958.1992.tb01399.x. [PubMed: 1357526].
  • 39. Bidet P, Bonacorsi S, Clermont O, De Montille C, Brahimi N, Bingen E. Multiple insertional events, restricted by the genetic background, have led to acquisition of pathogenicity island IIJ96-like domains among Escherichia coli strains of different clinical origins. Infect Immun. 2005;73(7):4081-7. doi: 10.1128/IAI.73.7.4081-4087.2005. [PubMed: 15972496]. [PubMed Central: PMC1168593].
  • 40. Robino L, Scavone P, Araujo L, Algorta G, Zunino P, Pirez MC, et al. Intracellular bacteria in the pathogenesis of Escherichia coli urinary tract infection in children. Clin Infect Dis. 2014;59(11):e158-64. doi: 10.1093/cid/ciu634. [PubMed: 25091303]. [PubMed Central: PMC4650771].
  • 41. Najafi A, Hasanpour M, Askary A, Aziemzadeh M, Hashemi N. Distribution of pathogenicity island markers and virulence factors in new phylogenetic groups of uropathogenic Escherichia coli isolates. Folia Microbiol (Praha). 2018;63(3):335-43. doi: 10.1007/s12223-017-0570-3. [PubMed: 29199378].
  • 42. Lopez-Banda DA, Carrillo-Casas EM, Leyva-Leyva M, Orozco-Hoyuela G, Manjarrez-Hernandez AH, Arroyo-Escalante S, et al. Identification of virulence factors genes in Escherichia coli isolates from women with urinary tract infection in Mexico. Biomed Res Int. 2014;2014:959206. doi: 10.1155/2014/959206. [PubMed: 24895634]. [PubMed Central: PMC4026957].
  • 43. Stone L. Microbiota: Bacteriophage diversity in the urinary microbiome. Nat Rev Urol. 2018;15(3):135. doi: 10.1038/nrurol.2018.23. [PubMed: 29460923].
  • 44. Baharoglu Z, Garriss G, Mazel D. Multiple pathways of genome plasticity leading to development of antibiotic resistance. Antibiotics (Basel). 2013;2(2):288-315. doi: 10.3390/antibiotics2020288. [PubMed: 27029305]. [PubMed Central: PMC4790341].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments