Jundishapur Journal of Microbiology

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The In Vitro Effect of Hydroalcoholic Extract of Artemisia absinthium on the Growth of Leishmania major (MRHO/IR/75/ER) in Peritoneal Macrophages from BALB/c Mice

Ali Rahiminejad 1 , 2 , Khosrow Hazrati Tappeh 1 , 2 , * , Shahram Seyyedi 3 and Peyman Mikaili 4
Authors Information
1 Cellular and Molecular Research Center, Urmia University of Medical Sciences, Urmia, Iran
2 Department of Parasitology and Mycology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
3 Department of Immunology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
4 Department of Pharmacology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
Article information
  • Jundishapur Journal of Microbiology: November 2018, 11 (11); e77302
  • Published Online: October 7, 2018
  • Article Type: Research Article
  • Received: May 12, 2018
  • Revised: September 24, 2018
  • Accepted: September 27, 2018
  • DOI: 10.5812/jjm.77302

To Cite: Rahiminejad A, Hazrati Tappeh K, Seyyedi S, Mikaili P. The In Vitro Effect of Hydroalcoholic Extract of Artemisia absinthium on the Growth of Leishmania major (MRHO/IR/75/ER) in Peritoneal Macrophages from BALB/c Mice, Jundishapur J Microbiol. 2018 ; 11(11):e77302. doi: 10.5812/jjm.77302.

Abstract
Copyright © 2018, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Mueller MS, Runyambo N, Wagner I, Borrmann S, Dietz K, Heide L. Randomized controlled trial of a traditional preparation of Artemisia annua L. (annual wormwood) in the treatment of malaria. Trans R Soc Trop Med Hyg. 2004;98(5):318-21. doi: 10.1016/j.trstmh.2003.09.001. [PubMed: 15109558].
  • 2. Akhoundi M, Kuhls K, Cannet A, Votypka J, Marty P, Delaunay P, et al. A historical overview of the classification, evolution, and dispersion of leishmania parasites and sandflies. PLoS Negl Trop Dis. 2016;10(3). e0004349. doi: 10.1371/journal.pntd.0004349. [PubMed: 26937644]. [PubMed Central: PMC4777430].
  • 3. Desjeux P. Leishmaniasis: Current situation and new perspectives. Comp Immunol Microbiol Infect Dis. 2004;27(5):305-18. doi: 10.1016/j.cimid.2004.03.004. [PubMed: 15225981].
  • 4. Hotez PJ, Savioli L, Fenwick A. Neglected tropical diseases of the Middle East and North Africa: Review of their prevalence, distribution, and opportunities for control. PLoS Negl Trop Dis. 2012;6(2). e1475. doi: 10.1371/journal.pntd.0001475. [PubMed: 22389729]. [PubMed Central: PMC3289601].
  • 5. Croft SL, Yardley V. Chemotherapy of leishmaniasis. Curr Pharm Des. 2002;8(4):319-42. [PubMed: 11860369].
  • 6. Mishra BB, Kale RR, Singh RK, Tiwari VK. Alkaloids: Future prospective to combat leishmaniasis. Fitoterapia. 2009;80(2):81-90. doi: 10.1016/j.fitote.2008.10.009. [PubMed: 19015012].
  • 7. Rocha LG, Almeida JR, Macedo RO, Barbosa-Filho JM. A review of natural products with antileishmanial activity. Phytomedicine. 2005;12(6-7):514-35. doi: 10.1016/j.phymed.2003.10.006. [PubMed: 16008131].
  • 8. Kolodziej H, Kiderlen AF. Antileishmanial activity and immune modulatory effects of tannins and related compounds on Leishmania parasitised RAW 264.7 cells. Phytochemistry. 2005;66(17):2056-71. doi: 10.1016/j.phytochem.2005.01.011. [PubMed: 16153409].
  • 9. Lamidi M, DiGiorgio C, Delmas F, Favel A, Eyele Mve-Mba C, Rondi ML, et al. In vitro cytotoxic, antileishmanial and antifungal activities of ethnopharmacologically selected Gabonese plants. J Ethnopharmacol. 2005;102(2):185-90. doi: 10.1016/j.jep.2005.06.011. [PubMed: 16046090].
  • 10. Khademvatan S, Adibpour N, Eskandari A, Rezaee S, Hashemitabar M, Rahim F. In silico and in vitro comparative activity of novel experimental derivatives against Leishmania major and Leishmania infantum promastigotes. Exp Parasitol. 2013;135(2):208-16. doi: 10.1016/j.exppara.2013.07.004. [PubMed: 23872452].
  • 11. Yousefi E, Eskandari A, Gharavi MJ, Khademvatan S. In vitro activity and cytotoxicity of Crocus sativus extract against Leihmania major (MRHO/IR/75/ER). Infect Disord Drug Targets. 2014;14(1):56-60. [PubMed: 25159304].
  • 12. Gharavi M, Nobakht M, Khademvatan S, Fani F, Bakhshayesh M, Roozbehani M. The effect of aqueous garlic extract on interleukin-12 and 10 levels in Leishmania major (MRHO/IR/75/ER) infected macrophages. Iran J Public Health. 2011;40(4):105-11. [PubMed: 23113109]. [PubMed Central: PMC3481747].
  • 13. Lachenmeier DW. Wormwood (Artemisia absinthium L.): A curious plant with both neurotoxic and neuroprotective properties? J Ethnopharmacol. 2010;131(1):224-7. doi: 10.1016/j.jep.2010.05.062. [PubMed: 20542104].
  • 14. Bahmani M, Saki K, Ezatpour B, Shahsavari S, Eftekhari Z, Jelodari M, et al. Leishmaniosis phytotherapy: Review of plants used in Iranian traditional medicine on leishmaniasis. Asian Pac J Trop Biomed. 2015;5(9):695-701. doi: 10.1016/j.apjtb.2015.05.018.
  • 15. Martinez-Diaz RA, Ibanez-Escribano A, Burillo J, Heras Lde L, Prado GD, Agullo-Ortuno MT, et al. Trypanocidal, trichomonacidal and cytotoxic components of cultivated Artemisia absinthium Linnaeus (Asteraceae) essential oil. Mem Inst Oswaldo Cruz. 2015;110(5):693-9. doi: 10.1590/0074-02760140129. [PubMed: 26107187]. [PubMed Central: PMC4569837].
  • 16. Khalili Dehkordi B, Rafieian M, Hejazi SH, Yusefi HA, Yektaian N, Shirani Bidabadi L. [Effect of Achillea millefolium, Artemisia absinthium and Juglans regia leaves extracts on Trichomonas vaginalis, in vitra]. J Shahrekord Univ Med Sci. 2011;12(4):62-9. Persian.
  • 17. Albakhit S, Doudi M. [The evaluation of Methanolic and aqueous extracts effect of Zizyphus spina-Christi against Leishmania major (MHOM/IR/75/ER) promastigotes using MTT assay]. Iran J Med Microbiol. 2016;10(3):54-60. Persian.
  • 18. Tavakkol Afshari J, Rakhshandeh H, Zamani AR, Mahdavi Shahri N, Ghazezadeh L, Norozi M, et al. [Cytotoxicity effects of citrullus colocynthis on Hep2 and L929 cell lines]. Hakim Res Journal. 2005;8(2):47-54. Persian.
  • 19. Dalimi A, Ghaffarifar F, Sadraei J. [Cytotoxic effects of 5-fluorouracil on Leishmania major promastigotes and induction of apoptosis in the parasite]. Sci J Ilam Univ Med Sci. 2014;21(7):34-42. Persian.
  • 20. Esavand Heydari F, Ghaffarifar F, Soflaei S, Dalimi A. Comparison between in vitro effects of aqueous extract of Artemisia seiberi and artemisinin on Leishmania major. Jundishapur J Nat Pharm Prod. 2013;8(2):70-5. [PubMed: 24624191]. [PubMed Central: PMC3941912].
  • 21. Shokrzadeh M, Parvaresh A, Shahani S, Habibi E, Zalzar Z. [Cytotoxic effects of lagenaria siceraria standl. extract on cancer cell lin]. J Mazandaran Univ Med Sci. 2013;22(97):225-30. Persian.
  • 22. Khademvatan S, Gharavi MJ, Akhlaghi L, Samadikuchaksaraei A, Mousavizadeh K, Hadighi R, et al. Induction of apoptosis by miltefosine in Iranian strain of Leishmania infantum promastigotes. Iran J Parasitol. 2009;4(2):23-31.
  • 23. Talari SA, Dorodgar A, Ouzougi J. [In vitro effect of various concentrations of hedera helix extract and glucantime on visceral leishmaniosis]. J Kashan Univ Med Sci (Feyz). 1997;1(2):61-7. Persian.
  • 24. Sadeghi-Nejad B, Saki J. Effect of aqueous allium cepa and ixora brachiata root extract on Leishmania major promastigotes. Jundishapur J Nat Pharm Prod. 2014;9(2). e15442. [PubMed: 24872942]. [PubMed Central: PMC4036374].
  • 25. Calixto JB. Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res. 2000;33(2):179-89. [PubMed: 10657057].
  • 26. Boadu AA, Asase A. Documentation of herbal medicines used for the treatment and management of human diseases by some communities in southern Ghana. Evid Based Complement Alternat Med. 2017;2017:3043061. doi: 10.1155/2017/3043061. [PubMed: 28684965]. [PubMed Central: PMC5480049].
  • 27. Calixto JB. Twenty-five years of research on medicinal plants in Latin America: A personal view. J Ethnopharmacol. 2005;100(1-2):131-4. doi: 10.1016/j.jep.2005.06.004. [PubMed: 16006081].
  • 28. Tariku Y, Hymete A, Hailu A, Rohloff J. In vitro evaluation of antileishmanial activity and toxicity of essential oils of Artemisia absinthium and Echinops kebericho. Chem Biodivers. 2011;8(4):614-23. doi: 10.1002/cbdv.201000331. [PubMed: 21480507].
  • 29. Gucwa K, Milewski S, Dymerski T, Szweda P. Investigation of the antifungal activity and mode of action of Thymus vulgaris, Citrus limonum, Pelargonium graveolens, Cinnamomum cassia, Ocimum basilicum, and Eugenia caryophyllus essential oils. Molecules. 2018;23(5). doi: 10.3390/molecules23051116. [PubMed: 29738503].
  • 30. Tiuman TS, Santos AO, Ueda-Nakamura T, Filho BP, Nakamura CV. Recent advances in leishmaniasis treatment. Int J Infect Dis. 2011;15(8):e525-32. doi: 10.1016/j.ijid.2011.03.021. [PubMed: 21605997].
  • 31. Da Silva BJM, Hage AAP, Silva EO, Rodrigues APD. Medicinal plants from the Brazilian Amazonian region and their antileishmanial activity: A review. J Integr Med. 2018;16(4):211-22. doi: 10.1016/j.joim.2018.04.004. [PubMed: 29691188].
  • 32. Dalimi A, Arbabi M, Naserifar R. [The effect of aqueous extraction of Artemisia sieberi besser and Scrophularia striata boiss. on Leishmania major under in vitro conditions]. Iran J Med Aromatic Plant. 2013;29(1). Persian. doi: 10.22092/ijmapr.2013.2904.
  • 33. Soosaraei M, Fakhar M, Hosseini Teshnizi S, Ziaei Hezarjaribi H, Banimostafavi ES. Medicinal plants with promising antileishmanial activity in Iran: A systematic review and meta-analysis. Ann Med Surg (Lond). 2017;21:63-80. doi: 10.1016/j.amsu.2017.07.057. [PubMed: 28794869]. [PubMed Central: PMC5536386].
  • 34. Nikmehr B, Ghaznavi H, Rahbar A, Sadr S, Mehrzadi S. In vitro anti-leishmanial activity of methanolic extracts of Calendula officinalis flowers, Datura stramonium seeds, and Salvia officinalis leaves. Chin J Nat Med. 2014;12(6):423-7. doi: 10.1016/S1875-5364(14)60066-2. [PubMed: 24969522].
  • 35. Maspi N, Ghafarifar F, Bahrami AM, Bastaminejad S, Shamsi M. Evaluation of leishmanicidal effect of watery and ethanolic flowers calendula officinalis extract on promastigotes of Leishmania major (MRHO/IR/75/ER) in vitro. J Ilam Univ Med Sci. 2010;18(1):28-33.
  • 36. Azizi K, Shahidi-Hakak F, Asgari Q, Hatam GR, Fakoorziba MR, Miri R, et al. In vitro efficacy of ethanolic extract of Artemisia absinthium (Asteraceae) against Leishmania major L. using cell sensitivity and flow cytometry assays. J Parasit Dis. 2016;40(3):735-40. doi: 10.1007/s12639-014-0569-5. [PubMed: 27605775]. [PubMed Central: PMC4996182].
  • 37. Malik M, Jividen K, Padmakumar VC, Cataisson C, Li L, Lee J, et al. Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation. Proc Natl Acad Sci U S A. 2012;109(16):6130-5. doi: 10.1073/pnas.1201351109. [PubMed: 22474389]. [PubMed Central: PMC3341024].
  • 38. Qadoumi M, Becker I, Donhauser N, Rollinghoff M, Bogdan C. Expression of inducible nitric oxide synthase in skin lesions of patients with american cutaneous leishmaniasis. Infect Immun. 2002;70(8):4638-42. [PubMed: 12117977]. [PubMed Central: PMC128200].

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