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Relative frequency of norovirus infection in children suffering from gastroenteritis referred to Aboozar hospital, Ahvaz, Iran


Shahram Jalilian 1 , Ali Reza Samarbaf-Zadeh 2 , * , Seyed Hamid Reza Mozhgani 1 , Manoochehr Makvandi 1 , Mehdi Parsa-nahad 1 , Roya Pirmoradi 1 , Ahmad Shamsi-Zadeh 1


1 Department of Medical Microbiology, School of Medicine and Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Science, IR Iran

2 Department of Medical Microbiology, School of Medicine and Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Science, Alirezasamarbaf_78@hotmail.com, IRIran


Jundishapur Journal of Microbiology: 5 (1); 355-358
Article Type: Research Article
Received: September 1, 2010
Accepted: June 1, 2011




Background: Noroviruses belong to the Norovirus genus in the Caliciviridae family. Norovi-ruses are the most common causes of gastroenteritis and have a great impact on public
health. They have been identified as a common cause of acute gastroenteritis in children.
Objectives: The aim of this study was to determine the prevalence of Norovirus in children
suffering from gastroenteritis.
Patients and Methods: Fecal samples (n = 143) were collected from children under 5 years of
age who were suffering from gastroenteritis. All the children were referred to Ahvaz Aboo-zar Hospital, located in southwestern Iran. Norovirus RNA was extracted by Trizol, and
RNA was detected using nested reverse transcriptase polymerase chain reaction (nested-RT-PCR).
Results: Norovirus infection was detected in 9 of the 143 collected samples (6.3%). All posi-tive samples belonged to genogroup II. Five positive samples were obtained from male
patients and 4 were obtained from female patients. Most of the positive cases were from
patients between 3 and 5 yars of age (n = 5, 56%). There was no relationship between gender
and virus prevalence. The rate of infection peaked in winter (n =6, 66.9%), and we did not
detect any positive cases in summer.
Conclusions: The prevalence of this virus in Ahvaz is similar to that reported by other re-searchers. Because this virus is transmitted by contaminated food or water, we recom-mend adult education and improved personal hygiene to reduce the incidence of Noro-virus infection in children. This study improves our epidemiological knowledge of the
prevalence of this virus in Ahvaz and Iran.

  • Implication for health policy/practice/research/medical education:
    This study improves our knowledge about the significance of noroviral gastroenteritis in clinics.
  • Please cite this paper as:
    Jalilian S, Samarbaf-Zadeh AR, Mozhgani SHR, Makvandi M, Parsa-nahad M, Pirmoradi R, et al. Relative Frequency of Norovirus Infection in Children Suffering From Gastroenteritis and Referred to Aboozar Hospital, Ahvaz, Iran. Jundishapur J Microbiol. 2012;5(1): 355-8. DOI: 10.5812/kowsar.20083645.2370
  • © 2012, AJUMS. Published by Kowsar M.P.Co. All rights reserved.


Human Norovirus Gastroenteritis Nested-RT-PCR

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