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Relative Frequency of Enteroviruses in Children With Aseptic Meningitis Referred to Aboozar Hospital in Ahvaz

AUTHORS

Mojtaba Rasti 1 , Ali Reza Samarbaf-Zadeh 2 , * , Manoochehr Makvandi 1 , Ahmad Shamsi-Zadeh 1

AUTHORS INFORMATION

1 Department of Medical Microbiology , School of Medicine , Ahvaz Jundishapur University of Medical Science, IR Iran

2 1) Department of Medical Microbiology , School of Medicine , Ahvaz Jundishapur University of Medical Science, 2)Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Science, alirezasamarbaf_78@hotmail.com, IR Iran

ARTICLE INFORMATION

Jundishapur Journal of Microbiology: 5 (3); 456-459
Article Type: Research Article
Received: September 20, 2011
Accepted: January 10, 2012
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Abstract

Background: Human Enteroviruses are members of the Picornaviridae family, they are nonenveloped,with icosahedral symmetry, positive RNA viruses and causes aseptic meningitis in both infants and adults.
Objectives: The aim of this study was to determine the relative frequency of Enteroviral meningitis among children referred to Ahvaz Aboozar hospital.
Patients and Methods: 57 Cerebrospinal fluid samples were collected from patients with aseptic meningitis and White Blood Cell (WBC) count of more than 5x106/mm3, Enterovirus RNA was extracted with Roch extraction kit and Enteroviral infection was detected by Revers Transcriptase polymerase chain reaction (RT-PCR) test.
Results: Enteroviral infection was detected in 34 cases out of 57 patient (59.6 %), 19 patients were younger than 1 year old (55.8 %), 8 cases were between 1 and 2 years (23.5 %) and 7 cases were older than 2 years (20.5 %). The relationship between gender and prevalence was not significant. Most cases were found in winter .
Conclusions: It was shown that human Enterovirus is the major cause of aseptic meningitis in Ahvaz, south west of Iran. The prevalence of Enterovirus infection was considerably high in this region. To decrease prevalence of Enteroviral infection, improved knowledge and personal hygiene is advised.


Implication for health policy/practice/research/medical education:
The data collected in this project assist paediatricians to manage infant gastroenteritis cases more effectively.

Please cite this paper as:
Rasti M, Samarbaf-Zadeh AR, Makvandi M, Shamsi-Zadeh A. Relative Frequency of Enteroviruses in Children With Aseptic Meningitis Referred to Aboozar Hospital in Ahvaz. Jundishapur J Mirobiol. 2012;5(3):456-9. DOI: 10.5812/jjm.2359

Copyright © 2012 Kowsar Corp. All rights reserved.


Keywords

Human Enterovirus Aseptic Meningitis Reverse Transcreaptase Polymerase Chain Reaction

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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