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Human Respiratory Syncytial Virus Infection and its Subgroups Among the Hospitalized Young Children With Acute Respiratory Infection

AUTHORS

Seyed Mohammad Alavi 1 , * , Manoochehr Makvandi 2 , Saeid Najafi Fard 2 , Leila Alavi 3

AUTHORS INFORMATION

1 Infectious and Tropical Diseases Research Center, Jundishapur University of Medical Sciences, Ahvaz, IR Iran

2 College of Medicine, Jundishapur University of Medical Sciences, Ahvaz, IR Iran

3 Food and Drug Deputy of Jundishapur University of Medical Sciences, Ahvaz, IR Iran

ARTICLE INFORMATION

Jundishapur Journal of Microbiology: 6 (8); 6452
Published Online: September 30, 2013
Article Type: Research Article
Received: May 20, 2012
Accepted: December 14, 2012
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Abstract

Background: Respiratory syncytial virus (RSV) can cause acute respiratory infection (ARI) in infants and young children.

Objectives: This study was conducted to determine the incidence of RSV infection and its subgroups among children with ARI.

Materials and Methods: A total of 100 throat samples were collected from hospitalized children with ARI in different hospitals across the Khuzestan province from June 2009 to April 2010. The samples were tested for RSV by the nested PCR. The product of positive RSV was sequenced to determine the RSV subgroup, followed by phylogenic tree.

Results: Of total 100 patients, 29 (29%) including 16 (16%) male and 13 (13%) female were found positive for RSV infection. All the RSV positive patients were subgroup A dominant. High prevalence of RSV (8%) was found among the children under one year in contrast to 2% RSV incidence among the age group 6 years.

Conclusions: This study revealed that RSV subgroup A is dominant among the young children especially in children less than one year of age.

Keywords

Respiratory Syncytial Virus Respiratory Tract Infection Children

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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