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Distribution of Hepatitis C Virus Genotypes Among Chronic Infected Injecting Drug Users in Tehran, Iran

AUTHORS

Fahimeh Ranjbar Kermani 1 , Zohreh Sharifi 1 , * , Fereshteh Ferdowsian 1 , Zahrah Paz 1 , Mahsa Zamanian 1

AUTHORS INFORMATION

1 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, IR Iran, z.sharifi@ibto.ir

ARTICLE INFORMATION

Jundishapur Journal of Microbiology: 6 (3); 265-8
Published Online: April 30, 2013
Article Type: Research Article
Received: April 16, 2012
Accepted: July 2, 2012
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Abstract

Background: Hepatitis C virus (HCV) is the main cause of infection that has the potential to cause chronic liver disease. Injecting drug users (IDUs) have a key role in HCV transmission in Iran. Knowledge of the distribution of various genotypes is essential for successful future research and control strategies.

Objectives: The aim of this study was to identify HCV genotypes among chronic infected injecting drug users (IDUs) in Tehran, Iran.

Patients and Methods: In this cross sectional study, we investigated HCV genotypes among 36 plasma samples from HCV infected IDUs (35 male and 1female, mean age: 33.67, and age range 20-62 years), referred to Research Center of Iranian Blood Transfusion Organization(IBTO) in Tehran from December 2008 to March 2009.HCV Genotyping was performed using type-specific primers.

Results: Genotypes 3a, 1a and 1b were found in 58.3 %, 25% and 16.7 % patients, respectively.

Conclusions: Our study demonstrated the high prevalence of genotype 3a among injecting drug users, which is also found in Europe and United states.

Keywords

Hepatitis C virus HCV Genotypes Injecting Drug Users Iran

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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