Central nervous system fungal infections; a review article
Jundishapur Journal of Microbiology: 3 (2); 41-47 Article Type: Research Article
April 1, 2010
April 1, 2010
M, Zarei Mahmoudabadi
A. Central nervous system fungal infections; a review article ,
Jundishapur J Microbiol.
Online ahead of Print
Central nervous system (CNS) fungal infections have a high rate of morbidity and mortality that increased during last three decades. CNS fungal infections present a diagnostic and therapeutic challenge. High numbers of organ transplants, chemotherapy patients, intensive care unit hospitalizations, immunocompromised patients and haematological malignancies increase morbidity and mortality. Several fungi including, saprophytic fungi, melanized fungi, dimorphic fungi, yeast and yeasts-likes cause CNS fungal infections. New antifungal, posaconazole, voriconazole and echinocandins as well as traditionally antifungal, amphotericine B, flucytosine and itraconazole were used for CNS fungal infection therapy.
CNS fungal infection, Candida, Cryptococcus, Saprophytic fungi, Dimorphic fungi
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