Jundishapur Journal of Microbiology

Published by: Kowsar

Extended-Spectrum Beta-Lactamases in Cystic Fibrosis Isolates of Klebsiella pneumoniae

Roya Rafiee 1 , * , Fereshteh Eftekhar 2 and Seyed Ahmad Tabatabaii 3
Authors Information
1 Radiation Applications Research School, Nuclear Science and Technology Research Institute, Tehran, Iran
2 Department of Microbiology, Faculty of Biological Sciences, Shahid Beheshti University, G.C., Tehran, Iran
3 Department of Pediatrics, Shahid Beheshti University of Medical Sciences, M.C., Tehran, Iran
Article information
  • Jundishapur Journal of Microbiology: January 2018, 11 (1); e61086
  • Published Online: November 30, 2017
  • Article Type: Research Article
  • Received: April 5, 2017
  • Revised: October 30, 2017
  • Accepted: November 22, 2017
  • DOI: 10.5812/jjm.61086

To Cite: Rafiee R, Eftekhar F, Tabatabaii S A. Extended-Spectrum Beta-Lactamases in Cystic Fibrosis Isolates of Klebsiella pneumoniae, Jundishapur J Microbiol. 2018 ; 11(1):e61086. doi: 10.5812/jjm.61086.

Copyright © 2017, Jundishapur Journal of Microbiology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
6. Conclusion
  • 1. Callaghan M, McClean S. Bacterial host interactions in cystic fibrosis. Curr Opin Microbiol. 2012;15(1):71-7. doi: 10.1016/j.mib.2011.11.001. [PubMed: 22137884].
  • 2. Lipuma JJ. The changing microbial epidemiology in cystic fibrosis. Clin Microbiol Rev. 2010;23(2):299-323. doi: 10.1128/CMR.00068-09. [PubMed: 20375354].
  • 3. Davies JC, Bilton D. Bugs, biofilms, and resistance in cystic fibrosis. Respir Care. 2009;54(5):628-40. [PubMed: 19393107].
  • 4. Leao RS, Pereira RH, Folescu TW, Albano RM, Santos EA, Junior LG, et al. KPC-2 carbapenemase-producing Klebsiella pneumoniae isolates from patients with Cystic Fibrosis. J Cyst Fibros. 2011;10(2):140-2. doi: 10.1016/j.jcf.2010.12.003. [PubMed: 21220216].
  • 5. Rampure R, Gangane R, Oli A, Chandrakanth K. Prevalence of MDR ESBL producing Klebsiella pneumoniae isolated from clinical samples. J Microbiol Biotech Res. 2013;3(1):32-9.
  • 6. Vali P, Shahcheraghi F, Seyfipour M, Zamani MA, Allahyar MR, Feizabadi MM. Phenotypic and genetic characterization of carbapenemase and ESBLs producing gram negative bacteria (GNB) isolated from patients with cystic fibrosis, (CF) in Tehran hospitals. J Clin Diagn Res. 2014;8(1):26-30. doi: 10.7860/JCDR/2014/6877.3916. [PubMed: 24596716].
  • 7. Khanbabaee G, Akbarizadeh M, Sayyari A, Ashayeri Panah M, Abdollahgorji F, Sheibani K, et al. A survey on pulmonary pathogens and their antibiotic susceptibility among cystic fibrosis patients. Braz J Infect Dis. 2012;16(2):122-8. [PubMed: 22552452].
  • 8. Pollini S, Maradei S, Fiscarelli E, Arena F, Galano A, Ricciotti G, et al. Emergence of extended spectrum beta lactamase producing Enterobacteriaceae in cystic fibrosis patients. Berlin, Germany: Poster P1241. Abstr 23rd Annu Meet, Eur Congr Clin Microbiol Infect Dis; 2013.
  • 9. Fiscarelli E, Pompilio A, Gherardi G, Ricciotti G. Is the lung of cystic fibrosis patients a reservoir of extended spectrum beta lactamase producing Enterobacteriaceae?. J Cyst Fibros. 2012;11:90. doi: 10.1016/s1569-1993(12)60305-1.
  • 10. Ramdani Bouguessa N, Manageiro V, Jones Dias D, Ferreira E, Tazir M, Canica M. Role of SHV beta lactamase variants in resistance of clinical Klebsiella pneumoniae strains to beta lactams in an Algerian hospital. J Med Microbiol. 2011;60(7):983-7. doi: 10.1099/jmm.0.030577-0. [PubMed: 21415202].
  • 11. Thomson KS. Extended spectrum beta lactamase, AmpC, and Carbapenemase issues. J Clin Microbiol. 2010;48(4):1019-25. doi: 10.1128/JCM.00219-10. [PubMed: 20181902].
  • 12. Bush K, Jacoby GA, Medeiros AA. A functional classification scheme for beta-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother. 1995;39(6):1211-33. [PubMed: 7574506].
  • 13. Poirel L, Naas T, Nordmann P. Diversity, epidemiology, and genetics of class D beta-lactamases. Antimicrob Agents Chemother. 2010;54(1):24-38. doi: 10.1128/AAC.01512-08. [PubMed: 19721065].
  • 14. Evans BA, Amyes SG. OXA beta-lactamases. Clin Microbiol Rev. 2014;27(2):241-63. doi: 10.1128/CMR.00117-13. [PubMed: 24696435].
  • 15. Clinical and laboratory standards institute . Performance standards for antimicrobial susceptibility testing. Wayne, PA, USA: CLIS; 2013.
  • 16. Pakzad I, Ghafourian S, Taherikalani M, Sadeghifard N, Abtahi H, Rahbar M, et al. qnr Prevalence in Extended Spectrum Beta-lactamases (ESBLs) and None-ESBLs Producing Escherichia coli Isolated from Urinary Tract Infections in Central of Iran. Iran J Basic Med Sci. 2011;14(5):458-64. [PubMed: 23493061].
  • 17. Karah N, Poirel L, Bengtsson S, Sundqvist M, Kahlmeter G, Nordmann P, et al. Plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in Escherichia coli and Klebsiella spp. from Norway and Sweden. Diagn Microbiol Infect Dis. 2010;66(4):425-31. doi: 10.1016/j.diagmicrobio.2009.12.004. [PubMed: 20226333].
  • 18. Nasehi L, Shahcheraghi F, Nikbin VS, Nematzadeh S. PER, CTX M, TEM and SHV beta lactamases in clinical isolates of Klebsiella pneumoniae isolated from Tehran, Iran. Iran J Basic Med Sci. 2010;13(3):111-8. doi: 10.22038/IJBMS.2010.5096.
  • 19. Weldhagen GF, Poirel L, Nordmann P. Ambler class A extended-spectrum beta-lactamases in Pseudomonas aeruginosa: novel developments and clinical impact. Antimicrob Agents Chemother. 2003;47(8):2385-92. [PubMed: 12878494].
  • 20. Huang SR, Liu MF, Lin CF, Shi ZY. Molecular surveillance and clinical outcomes of carbapenem-resistant Escherichia coli and Klebsiella pneumoniae infections. J Microbiol Immunol Infect. 2014;47(3):187-96. doi: 10.1016/j.jmii.2012.08.029. [PubMed: 23200553].
  • 21. Ashayeri-Panah M, Eftekhar F, Feizabadi MM. Development of an optimized random amplified polymorphic DNA protocol for fingerprinting of Klebsiella pneumoniae. Lett Appl Microbiol. 2012;54(4):272-9. doi: 10.1111/j.1472-765X.2012.03203.x. [PubMed: 22220979].
  • 22. Canton R, Morosini MI, Ballestero S, Alvarez ME, Escobar H, Maiz L, et al. Lung colonization with Enterobacteriaceae producing extended spectrum β Lactamases in cystic fibrosis patients. Pediatr Pulmonol. 1997;24(3):213-7. doi: 10.1002/(SICI)1099-0496(199709)24:3<213::AID-PPUL7>3.0.CO;2-N.
  • 23. Livermore DM, Hawkey PM. CTX-M: changing the face of ESBLs in the UK. J Antimicrob Chemother. 2005;56(3):451-4. doi: 10.1093/jac/dki239. [PubMed: 16006451].
  • 24. Paterson DL, Bonomo RA. Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev. 2005;18(4):657-86. doi: 10.1128/CMR.18.4.657-686.2005. [PubMed: 16223952].
  • 25. Duvernay C, Coulange L, Dutilh B, Dubois V, Quentin C, Arpin C. Duplication of the chromosomal blaSHV-11 gene in a clinical hypermutable strain of Klebsiella pneumoniae. Microbiology. 2011;157(Pt 2):496-503. doi: 10.1099/mic.0.043885-0. [PubMed: 20966089].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments