Jundishapur Journal of Microbiology

Published by: Kowsar

Determining Major Genotypes of Hepatitis C Virus Among Transplant Recipients by Real-Time Polymerase Chain Reaction Assay

Roya Feyznezhad 1 , Mohammad Amin Behzadi 2 , 3 , Ramin Yaghobi 4 and Mazyar Ziyaeyan 2 , *
Authors Information
1 Department of Microbiology, Sciences and Research Branch, Islamic Azad University, Shiraz, IR Iran
2 Alborzi Clinical Microbiology Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 Student Research Committee, Shiraz University of Medical Sciences, Shiraz, IR Iran
4 Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Article information
  • Jundishapur Journal of Microbiology: February 2015, 8 (2); e59779
  • Published Online: February 20, 2015
  • Article Type: Research Article
  • Received: December 9, 2013
  • Revised: June 8, 2014
  • Accepted: June 24, 2014
  • DOI: 10.5812/jjm.16722

To Cite: Feyznezhad R, Behzadi M A, Yaghobi R, Ziyaeyan M. Determining Major Genotypes of Hepatitis C Virus Among Transplant Recipients by Real-Time Polymerase Chain Reaction Assay, Jundishapur J Microbiol. 2015 ; 8(2):e59779. doi: 10.5812/jjm.16722.

Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Kapoor A, Simmonds P, Scheel TK, Hjelle B, Cullen JM, Burbelo PD, et al. Identification of rodent homologs of hepatitis C virus and pegiviruses. MBio. 2013; 4(2)-3[DOI][PubMed]
  • 2. Nakano T, Lau GM, Lau GM, Sugiyama M, Mizokami M. An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region. Liver Int. 2012; 32(2): 339-45[DOI][PubMed]
  • 3. Behzadi MA, Ziyaeyan M. Hepatitis C Virus Load in Seropositive Liver and Kidney Transplant Recipients by Quantitative Real-Time PCR Before and After Transplantation. Jundishapur J Microbiol. 2013; 6(8)[DOI]
  • 4. Berenguer M. Natural history of recurrent hepatitis C. Liver Transpl. 2002; 8(10 Suppl 1)-8[DOI][PubMed]
  • 5. Fishman JA, Rubin RH, Koziel MJ, Periera BJ. Hepatitis C virus and organ transplantation. Transplantation. 1996; 62(2): 147-54[PubMed]
  • 6. Pereira BJ. Renal transplantation in patients positive for hepatitis B or C (con). Transplant Proc. 1998; 30(5): 2070-2[PubMed]
  • 7. Kamar N, Alric L, Izopet J, Rostaing L. Hepatitis C virus and kidney disease. Clin Res Hepatol Gastroenterol. 2013; 37(4): 328-33[DOI][PubMed]
  • 8. Morales JM, Aguado JM. Hepatitis C and renal transplantation. Curr Opin Organ Transplant. 2012; 17(6): 609-15[DOI][PubMed]
  • 9. Aoufi Rabih S, Garcia Agudo R. Management of HCV infection in chronic kidney disease. Nefrologia. 2011; 31(3): 260-7[DOI][PubMed]
  • 10. Latt N, Alachkar N, Gurakar A. Hepatitis C virus and its renal manifestations: a review and update. Gastroenterol Hepatol (N Y). 2012; 8(7): 434-45[PubMed]
  • 11. Behzad-Behbahani A, Mojiri A, Tabei SZ, Farhadi-Andarabi A, Pouransari R, Yaghobi R, et al. Outcome of hepatitis B and C virus infection on graft function after renal transplantation. Transplant Proc. 2005; 37(7): 3045-7[DOI][PubMed]
  • 12. Roche B, Samuel D. Hepatitis C virus treatment pre- and post-liver transplantation. Liver Int. 2012; 32 Suppl 1: 120-8[DOI][PubMed]
  • 13. Chou R, Hartung D, Rahman B, Wasson N, Cottrell EB, Fu R. Comparative effectiveness of antiviral treatment for hepatitis C virus infection in adults: a systematic review. Ann Intern Med. 2013; 158(2): 114-23[PubMed]
  • 14. Zein NN. Clinical significance of hepatitis C virus genotypes. Clin Microbiol Rev. 2000; 13(2): 223-35[PubMed]
  • 15. Keyvani H, Alizadeh AH, Alavian SM, Ranjbar M, Hatami S. Distribution frequency of hepatitis C virus genotypes in 2231 patients in Iran. Hepatol Res. 2007; 37(2): 101-3[DOI][PubMed]
  • 16. Samimi-Rad K, Nategh R, Malekzadeh R, Norder H, Magnius L. Molecular epidemiology of hepatitis C virus in Iran as reflected by phylogenetic analysis of the NS5B region. J Med Virol. 2004; 74(2): 246-52[DOI][PubMed]
  • 17. Zali MR, Mayumi M, Raoufi M, Nowroozi A. Hepatitis C virus genotypes in the Islamic Republic of Iran: a preliminary study. East Mediterr Health J. 2000; 6(2-3): 372-7[PubMed]
  • 18. Jahanbakhsh Sefidi F, Keyvani H, Monavari SH, Alavian SM, Fakhim S, Bokharaei-Salim F. Distribution of hepatitis C virus genotypes in Iranian chronic infected patients. Hepat Month. 2013; 13(1)[DOI][PubMed]
  • 19. Ramia S, Eid-Fares J. Distribution of hepatitis C virus genotypes in the Middle East. Int J Infect Dis. 2006; 10(4): 272-7[DOI][PubMed]
  • 20. Lok AS, Chien D, Choo QL, Chan TM, Chiu EK, Cheng IK, et al. Antibody response to core, envelope and nonstructural hepatitis C virus antigens: comparison of immunocompetent and immunosuppressed patients. Hepatology. 1993; 18(3): 497-502[PubMed]
  • 21. Thio CL, Nolt KR, Astemborski J, Vlahov D, Nelson KE, Thomas DL. Screening for hepatitis C virus in human immunodeficiency virus-infected individuals. J Clin Microbiol. 2000; 38(2): 575-7[PubMed]
  • 22. Joukar F, Khalesi AK, Jafarshad R, Rahimabadi MS, Mansour-Ghanaei F. Distribution of hepatitis C virus genotypes in haemodialysis patients of Guilan, northern Islamic Republic of Iran. East Mediterr Health J. 2012; 18(3): 236-40[PubMed]
  • 23. Chakravarti A, Dogra G, Verma V, Srivastava AP. Distribution pattern of HCV genotypes & its association with viral load. Indian J Med Res. 2011; 133: 326-31[PubMed]
  • 24. Payan C, Roudot-Thoraval F, Marcellin P, Bled N, Duverlie G, Fouchard-Hubert I, et al. Changing of hepatitis C virus genotype patterns in France at the beginning of the third millenium: The GEMHEP GenoCII Study. J Viral Hepat. 2005; 12(4): 405-13[DOI][PubMed]
  • 25. Ross RS, Viazov S, Renzing-Kohler K, Roggendorf M. Changes in the epidemiology of hepatitis C infection in Germany: shift in the predominance of hepatitis C subtypes. J Med Virol. 2000; 60(2): 122-5[PubMed]
  • 26. Seme K, Vrhovac M, Mocilnik T, Maticic M, Lesnicar G, Baklan Z, et al. Hepatitis C virus genotypes in 1,504 patients in Slovenia, 1993-2007. J Med Virol. 2009; 81(4): 634-9[DOI][PubMed]
  • 27. Alavian SM, Gholami B, Masarrat S. Hepatitis C risk factors in Iranian volunteer blood donors: a case-control study. J Gastroenterol Hepatol. 2002; 17(10): 1092-7[PubMed]
  • 28. Chlabicz S, Flisiak R, Lapinski TW, Kowalczuk O, Wiercinska-Drapalo A, Pytel-Krolczuk B, et al. Epidemiological features of patients infected with HCV genotype 4 in Poland: Epidemiology of HCV genotype 4 in Poland. Hepat Month. 2011; 11(3): 191-4[PubMed]
  • 29. Savvas SP, Koskinas J, Sinani C, Hadziyannis A, Spanou F, Hadziyannis SJ. Changes in epidemiological patterns of HCV infection and their impact on liver disease over the last 20 years in Greece. J Viral Hepat. 2005; 12(5): 551-7[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments