Jundishapur Journal of Microbiology

Published by: Kowsar

Polyclonal Distribution of blaOXA-23 Gene Among Acinetobacter baumannii Isolated from Intensive Care Unit Patients in Tehran; Pulsed-Field Gel Electrophoresis Analysis

Mahdi Akbari Dehbalaei 1 , Shahin Najar-Peerayeh 1 , * , Mehrdad Behmanesh 2 and Morovat Taherikalani 3
Authors Information
1 Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2 Department of Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, IR Iran
3 Razi Herbal Medicines Research Center, Department of Microbiology, School of Medicine, Lorestan University of Medical Science, Khorramabad, Iran
Article information
  • Jundishapur Journal of Microbiology: January 2018, 11 (1); e58032
  • Published Online: November 20, 2017
  • Article Type: Research Article
  • Received: July 23, 2017
  • Revised: August 2, 2017
  • Accepted: October 4, 2017
  • DOI: 10.5812/jjm.58032

To Cite: Akbari Dehbalaei M, Najar-Peerayeh S, Behmanesh M, Taherikalani M. Polyclonal Distribution of blaOXA-23 Gene Among Acinetobacter baumannii Isolated from Intensive Care Unit Patients in Tehran; Pulsed-Field Gel Electrophoresis Analysis, Jundishapur J Microbiol. 2018 ; 11(1):e58032. doi: 10.5812/jjm.58032.

Abstract
Copyright © 2017, Jundishapur Journal of Microbiology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
6. Conclusion
Acknowledgements
Footnotes
References
  • 1. Lee SO, Kim NJ, Choi SH, Hyong Kim T, Chung JW, Woo JH, et al. Risk factors for acquisition of imipenem-resistant Acinetobacter baumannii: a case-control study. Antimicrob Agents Chemother. 2004;48(1):224-8. doi: 10.1128/AAC.48.1.224-228.2004. [PubMed: 14693543].
  • 2. Jung JY, Park MS, Kim SE, Park BH, Son JY, Kim EY, et al. Risk factors for multi-drug resistant Acinetobacter baumannii bacteremia in patients with colonization in the intensive care unit. BMC Infect Dis. 2010;10:228. doi: 10.1186/1471-2334-10-228. [PubMed: 20670453].
  • 3. Maragakis LL, Perl TM. Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options. Clin Infect Dis. 2008;46(8):1254-63. doi: 10.1086/529198. [PubMed: 18444865].
  • 4. Centers for Disease Control and Prevention . Assisted Reproductive Technology: Fertility Clinic Success Rates Report. CDC; 2013.
  • 5. Karmostaji A, Najar Peerayeh S, Hatef Salmanian A. Distribution of OXA-type class D β-lactamase genes among nosocomial multi drug resistant acinetobacter baumannii isolated in Tehran hospitals. Jundishapur J Microbiol. 2013;6(5). doi: 10.5812/jjm.8219.
  • 6. Alaei N, Aziemzadeh M, Bahador A. Antimicrobial resistance profiles and genetic elements involved in carbapenem resistance in Acinetobacter baumannii isolates from a referral hospital in Southern Iran. J Glob Antimicrob Resist. 2016;5:75-9. doi: 10.1016/j.jgar.2015.12.005. [PubMed: 27436472].
  • 7. Chung DR, Song JH, Kim SH, Thamlikitkul V, Huang SG, Wang H, et al. High prevalence of multidrug-resistant nonfermenters in hospital-acquired pneumonia in Asia. Am J Respir Crit Care Med. 2011;184(12):1409-17. doi: 10.1164/rccm.201102-0349OC. [PubMed: 21920919].
  • 8. Dhanoa A, Rajasekaram G, Lean SS, Cheong YM, Thong KL. Endemicity of Acinetobacter calcoaceticus-baumannii Complex in an Intensive Care Unit in Malaysia. J Pathog. 2015;2015:789265. doi: 10.1155/2015/789265. [PubMed: 26819759].
  • 9. Durmaz R, Otlu B, Koksal F, Hosoglu S, Ozturk R, Ersoy Y, et al. The optimization of a rapid pulsed-field gel electrophoresis protocol for the typing of Acinetobacter baumannii, Escherichia coli and Klebsiella spp. Jpn J Infect Dis. 2009;62(5):372-7. [PubMed: 19762987].
  • 10. Clinical and Laboratory Standards Institute . Performance standards for antimicrobial susceptibility testing: twenty-second informational supplement DM-SW. PA: CLSI; 2007.
  • 11. Woodford N, Ellington MJ, Coelho JM, Turton JF, Ward ME, Brown S, et al. Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents. 2006;27(4):351-3. doi: 10.1016/j.ijantimicag.2006.01.004. [PubMed: 16564159].
  • 12. Chu YW, Cheung TK, Chu MY, Lo JY, Dijkshoorn L. OXA-23-type imipenem resistance in Acinetobacter baumannii in Hong Kong. Int J Antimicrob Agents. 2009;34(3):285-6. doi: 10.1016/j.ijantimicag.2009.03.010. [PubMed: 19394202].
  • 13. Dillon B, Thomas L, Mohmand G, Zelynski A, Iredell J. Multiplex PCR for screening of integrons in bacterial lysates. J Microbiol Methods. 2005;62(2):221-32. doi: 10.1016/j.mimet.2005.02.007. [PubMed: 16009279].
  • 14. Zhang Y, Yao Z, Zhan S, Yang Z, Wei D, Zhang J, et al. Disease burden of intensive care unit-acquired pneumonia in China: a systematic review and meta-analysis. Int J Infect Dis. 2014;29:84-90. doi: 10.1016/j.ijid.2014.05.030. [PubMed: 25449241].
  • 15. Mohajeri P, Farahani A, Feizabadi MM, Ketabi H, Abiri R, Najafi F. Antimicrobial susceptibility profiling and genomic diversity of Acinetobacter baumannii isolates: A study in western Iran. Iran J Microbiol. 2013;5(3):195-202. [PubMed: 24475323].
  • 16. Shahcheraghi F, Abbasalipour M, Feizabadi M, Ebrahimipour G, Akbari N. Isolation and genetic characterization of metallo-beta-lactamase and carbapenamase producing strains of Acinetobacter baumannii from patients at Tehran hospitals. Iran J Microbiol. 2011;3(2):68-74. [PubMed: 22347585].
  • 17. Falagas ME, Koletsi PK, Bliziotis IA. The diversity of definitions of multidrug-resistant (MDR) and pandrug-resistant (PDR) Acinetobacter baumannii and Pseudomonas aeruginosa. J Med Microbiol. 2006;55(Pt 12):1619-29. doi: 10.1099/jmm.0.46747-0. [PubMed: 17108263].
  • 18. Moradi J, Hashemi FB, Bahador A. Antibiotic Resistance of Acinetobacter baumannii in Iran: A Systemic Review of the Published Literature. Osong Public Health Res Perspect. 2015;6(2):79-86. doi: 10.1016/j.phrp.2014.12.006. [PubMed: 25938016].
  • 19. Piana A, Palmieri A, Deidda S, Mura E, Are BM, Rubino S, et al. Molecular typing of XDR Acinetobacter baumannii strains in an Italian ICU. Epidemiol Prev. 2015;39(4 Suppl 1):129-33. [PubMed: 26499430].
  • 20. Villalon P, Valdezate S, Medina-Pascual MJ, Rubio V, Vindel A, Saez-Nieto JA. Clonal diversity of nosocomial epidemic Acinetobacter baumannii strains isolated in Spain. J Clin Microbiol. 2011;49(3):875-82. doi: 10.1128/JCM.01026-10. [PubMed: 21177889].
  • 21. Hu Y, Li B, Jin D, Cui Z, Tao X, Zhang B, et al. Comparison of multiple-locus variable-number tandem-repeat analysis with pulsed-field gel electrophoresis typing of Acinetobacter baumannii in China. J Clin Microbiol. 2013;51(4):1263-8. doi: 10.1128/JCM.03108-12. [PubMed: 23345295].
  • 22. Poirel L, Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect. 2006;12(9):826-36. doi: 10.1111/j.1469-0691.2006.01456.x. [PubMed: 16882287].
  • 23. Shoja S, Moosavian M, Rostami S, Abbasi F, Tabatabaiefar MA, Peymani A. Characterization of Oxacillinase and Metallo-beta-Lactamas Genes and Molecular Typing of Clinical Isolates of Acinetobacter baumannii in Ahvaz, South-West of Iran. Jundishapur J Microbiol. 2016;9(5). e32388. doi: 10.5812/jjm.32388. [PubMed: 27540456].
  • 24. Aliramezani A, Douraghi M, Hajihasani A, Mohammadzadeh M, Rahbar M. Clonal relatedness and biofilm formation of OXA-23-producing carbapenem resistant Acinetobacter baumannii isolates from hospital environment. Microb Pathog. 2016;99:204-8. doi: 10.1016/j.micpath.2016.08.034. [PubMed: 27569533].
  • 25. Fouad M, Attia AS, Tawakkol WM, Hashem AM. Emergence of carbapenem-resistant Acinetobacter baumannii harboring the OXA-23 carbapenemase in intensive care units of Egyptian hospitals. Int J Infect Dis. 2013;17(12):e1252-4. doi: 10.1016/j.ijid.2013.07.012. [PubMed: 24084245].
  • 26. Principe L, Piazza A, Giani T, Bracco S, Caltagirone MS, Arena F, et al. Epidemic diffusion of OXA-23-producing Acinetobacter baumannii isolates in Italy: results of the first cross-sectional countrywide survey. J Clin Microbiol. 2014;52(8):3004-10. doi: 10.1128/JCM.00291-14. [PubMed: 24920776].
  • 27. Bahador A, Raoofian R, Farshadzadeh Z, Beitollahi L, Khaledi A, Rahimi S, et al. The prevalence of ISAba1 and ISAba4 in acinetobacter baumannii species of different international clone lineages among patients with burning in Tehran, Iran. Jundishapur J Microbiol. 2015;8(6). doi: 10.5812/jjm.17167v2.
  • 28. Salimizand H, Noori N, Meshkat Z, Ghazvini K, Amel SJ. Prevalence of Acinetobacter baumannii harboring ISAba1/bla OXA-23-like family in a burn center. Burns. 2015;41(5):1100-6. doi: 10.1016/j.burns.2014.12.008. [PubMed: 25603980].
  • 29. Corvec S, Poirel L, Naas T, Drugeon H, Nordmann P. Genetics and expression of the carbapenem-hydrolyzing oxacillinase gene blaOXA-23 in Acinetobacter baumannii. Antimicrob Agents Chemother. 2007;51(4):1530-3. doi: 10.1128/AAC.01132-06. [PubMed: 17220422].
  • 30. Evans BA, Amyes SG. OXA beta-lactamases. Clin Microbiol Rev. 2014;27(2):241-63. doi: 10.1128/CMR.00117-13. [PubMed: 24696435].
  • 31. Figueiredo S, Poirel L, Croize J, Recule C, Nordmann P. In vivo selection of reduced susceptibility to carbapenems in Acinetobacter baumannii related to ISAba1-mediated overexpression of the natural bla(OXA-66) oxacillinase gene. Antimicrob Agents Chemother. 2009;53(6):2657-9. doi: 10.1128/AAC.01663-08. [PubMed: 19307373].
  • 32. Evans BA, Hamouda A, Amyes SG. The rise of carbapenem-resistant Acinetobacter baumannii. Curr Pharm Des. 2013;19(2):223-38. doi: 10.2174/1381612811306020223. [PubMed: 22894617].
  • 33. Pagano M, Martins AF, Machado AB, Barin J, Barth AL. Carbapenem-susceptible Acinetobacter baumannii carrying the ISAba1 upstream blaOXA-51-like gene in Porto Alegre, southern Brazil. Epidemiol Infect. 2013;141(2):330-3. doi: 10.1017/S095026881200074X. [PubMed: 22717017].
  • 34. Lin YC, Hsia KC, Chen YC, Sheng WH, Chang SC, Liao MH, et al. Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. Antimicrob Agents Chemother. 2010;54(5):2078-84. doi: 10.1128/AAC.01398-09. [PubMed: 20194701].
  • 35. Mohajeri P, Farahani A, Mehrabzadeh RS. Molecular Characterization of Multidrug Resistant Strains of Acinetobacter baumannii Isolated from Intensive Care Units in West of Iran. J Clin Diagn Res. 2017;11(2):DC20-2. doi: 10.7860/JCDR/2017/21156.9397. [PubMed: 28384861].
  • 36. Bahador A, Raoofian R, Pourakbari B, Taheri M, Hashemizadeh Z, Hashemi FB. Genotypic and antimicrobial susceptibility of carbapenem-resistant acinetobacter baumannii: analysis of is aba elements and blaOXA-23-like genes including a new variant. Front Microbiol. 2015;6. doi: 10.3389/fmicb.2015.01249.
  • 37. Anvarinejad M, Japoni A, Davarpanah MA, Mahmudi H, Mammina C, Vazin A. Phenotypic and Molecular Epidemiology of Acinetobacter calcoaceticus baumannii Complex Strains Spread at Nemazee Hospital of Shiraz, Iran. Jundishapur J Microbiol. 2015;8(6). e19180. doi: 10.5812/jjm.8(5)2015.19180. [PubMed: 26322204].
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