Jundishapur Journal of Microbiology

Published by: Kowsar

Patterns of Efflux Pump Genes Among Tetracycline Resistance Uropathogenic Escherichia coli Isolates Obtained From Human Urinary Infections

Sahar Nouri Gharajalar 1 , * and Vahideh Hamidi Sofiani 2
Authors Information
1 Department of Pathobiology, Faculty of Veterinary Medicine, Tabriz University, Tabriz, IR Iran
2 Faculty of Veterinary Medicine, Tabriz University, Tabriz, IR Iran
Article information
  • Jundishapur Journal of Microbiology: February 01, 2017, 10 (2); e40884
  • Published Online: January 14, 2017
  • Article Type: Research Article
  • Received: July 17, 2016
  • Revised: December 18, 2016
  • Accepted: January 7, 2017
  • DOI: 10.5812/jjm.40884

To Cite: Nouri Gharajalar S, Hamidi Sofiani V. Patterns of Efflux Pump Genes Among Tetracycline Resistance Uropathogenic Escherichia coli Isolates Obtained From Human Urinary Infections, Jundishapur J Microbiol. 2017 ; 10(2):e40884. doi: 10.5812/jjm.40884.

Copyright © 2017, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia coli. Nat Rev Microbiol. 2004; 2(2): 123-40[DOI][PubMed]
  • 2. Kibret M, Abera B. Antimicrobial susceptibility patterns of E. coli from clinical sources in northeast Ethiopia. Afr Health Sci. 2011; 11 Suppl 1-5[PubMed]
  • 3. Schroeder CM, Zhao C, DebRoy C, Torcolini J, Zhao S, White DG, et al. Antimicrobial resistance of Escherichia coli O157 isolated from humans, cattle, swine, and food. Appl Environ Microbiol. 2002; 68(2): 576-81[PubMed]
  • 4. Raum E, Lietzau S, von Baum H, Marre R, Brenner H. Changes in Escherichia coli resistance patterns during and after antibiotic therapy: a longitudinal study among outpatients in Germany. Clin Microbiol Infect. 2008; 14(1): 41-8[DOI][PubMed]
  • 5. Chopra I, Roberts M. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev. 2001; 65(2): 232-60[DOI][PubMed]
  • 6. Webber MA, Piddock LJ. The importance of efflux pumps in bacterial antibiotic resistance. J Antimicrob Chemother. 2003; 51(1): 9-11[PubMed]
  • 7. Bryan A, Shapir N, Sadowsky MJ. Frequency and distribution of tetracycline resistance genes in genetically diverse, nonselected, and nonclinical Escherichia coli strains isolated from diverse human and animal sources. Appl Environ Microbiol. 2004; 70(4): 2503-7[PubMed]
  • 8. Sayah RS, Kaneene JB, Johnson Y, Miller R. Patterns of antimicrobial resistance observed in Escherichia coli isolates obtained from domestic- and wild-animal fecal samples, human septage, and surface water. Appl Environ Microbiol. 2005; 71(3): 1394-404[DOI][PubMed]
  • 9. Sharma S, Mahajan B, Patidar RK, Sahare KN, Khare M, Singh V. Molecular Detection of Antimicrobial Resistance Genes in Biofilm Forming Escherichia Coli. Am J Pharm Health Res. 2013; 1: 2321-3647
  • 10. Karami N, Nowrouzian F, Adlerberth I, Wold AE. Tetracycline resistance in Escherichia coli and persistence in the infantile colonic microbiota. Antimicrob Agents Chemother. 2006; 50(1): 156-61[DOI][PubMed]
  • 11. CLSI, document. : M 100-S25. Performance standards for antimicrobial susceptibility testing. 25nd informational supplement. 2015;
  • 12. Aminov RI, Chee-Sanford JC, Garrigues N, Teferedegne B, Krapac IJ, White BA, et al. Development, validation, and application of PCR primers for detection of tetracycline efflux genes of gram-negative bacteria. Appl Environ Microbiol. 2002; 68(4): 1786-93[PubMed]
  • 13. Hammerum AM, Heuer OE. Human health hazards from antimicrobial-resistant Escherichia coli of animal origin. Clin Infect Dis. 2009; 48(7): 916-21[DOI][PubMed]
  • 14. Shariff V, Shenoy MS, Yadav T, M R. The antibiotic susceptibility patterns of uropathogenic Escherichia coli, with special reference to the fluoroquinolones. J Clin Diagn Res. 2013; 7(6): 1027-30[DOI][PubMed]
  • 15. Ozgumus OB, Celik-Sevim E, Alpay-Karaoglu S, Sandalli C, Sevim A. Molecular characterization of antibiotic resistant Escherichia coli strains isolated from tap and spring waters in a coastal region in Turkey. J Microbiol. 2007; 45(5): 379-87[PubMed]
  • 16. Jones CH, Tuckman M, Murphy E, Bradford PA. Identification and sequence of a tet(M) tetracycline resistance determinant homologue in clinical isolates of Escherichia coli. J Bacteriol. 2006; 188(20): 7151-64[DOI][PubMed]
  • 17. Tuckman M, Petersen PJ, Howe AY, Orlowski M, Mullen S, Chan K, et al. Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline. Antimicrob Agents Chemother. 2007; 51(9): 3205-11[DOI][PubMed]
  • 18. Blake DP, Humphry RW, Scott KP, Hillman K, Fenlon DR, Low JC. Influence of tetracycline exposure on tetracycline resistance and the carriage of tetracycline resistance genes within commensal Escherichia coli populations. J Appl Microbiol. 2003; 94(6): 1087-97[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments