Jundishapur Journal of Microbiology

Published by: Kowsar

The Prevalence and Genotype Distribution of Cervical Human Papillomavirus DNA in Women with Normal Cytology in North of Iran

Fatemeh Daneshvar 1 , Mohammadreza Haghshenas 1 , * , Fereshteh Majleci 2 and Abbas Rahimi 2
Authors Information
1 Molecular and Cell Biology Research Centre, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
2 Faculty of Health, Tehran University of Medical Sciences, Tehran, Iran
Article information
  • Jundishapur Journal of Microbiology: January 01, 2017, 10 (1); e40823
  • Published Online: December 13, 2016
  • Article Type: Research Article
  • Received: August 30, 2016
  • Revised: November 28, 2016
  • Accepted: December 4, 2016
  • DOI: 10.5812/jjm.40823

To Cite: Daneshvar F, Haghshenas M, Majleci F, Rahimi A. The Prevalence and Genotype Distribution of Cervical Human Papillomavirus DNA in Women with Normal Cytology in North of Iran, Jundishapur J Microbiol. 2017 ; 10(1):e40823. doi: 10.5812/jjm.40823.

Copyright © 2016, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Forouzanfar MH, Foreman KJ, Delossantos AM, Lozano R, Lopez AD, Murray CJ, et al. Breast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysis. Lancet. 2011; 378(9801): 1461-84[DOI][PubMed]
  • 2. Woodman CB, Collins SI, Young LS. The natural history of cervical HPV infection: unresolved issues. Nat Rev Cancer. 2007; 7(1): 11-22[DOI][PubMed]
  • 3. Boffetta P, Parkin DM. Cancer in developing countries. CA Cancer J Clin. 1994; 44(2): 81-90[PubMed]
  • 4. Arbyn M, Castellsague X, de Sanjose S, Bruni L, Saraiya M, Bray F, et al. Worldwide burden of cervical cancer in 2008. Ann Oncol. 2011; 22(12): 2675-86[DOI][PubMed]
  • 5. Kjaer SK, van den Brule AJ, Bock JE, Poll PA, Engholm G, Sherman ME, et al. Human papillomavirus--the most significant risk determinant of cervical intraepithelial neoplasia. Int J Cancer. 1996; 65(5): 601-6[DOI][PubMed]
  • 6. Lanham S, Herbert A, Basarab A, Watt P. Detection of cervical infections in colposcopy clinic patients. J Clin Microbiol. 2001; 39(8): 2946-50[DOI][PubMed]
  • 7. Moberg M, Gustavsson I, Gyllensten U. Real-time PCR-based system for simultaneous quantification of human papillomavirus types associated with high risk of cervical cancer. J Clin Microbiol. 2003; 41(7): 3221-8[PubMed]
  • 8. Kraus I, Molden T, Holm R, Lie AK, Karlsen F, Kristensen GB, et al. Presence of E6 and E7 mRNA from human papillomavirus types 16, 18, 31, 33, and 45 in the majority of cervical carcinomas. J Clin Microbiol. 2006; 44(4): 1310-7[DOI][PubMed]
  • 9. Cogliano V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, et al. Carcinogenicity of human papillomaviruses. Lancet Oncol. 2005; 6(4): 204[PubMed]
  • 10. Hebner CM, Laimins LA. Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity. Rev Med Virol. 2006; 16(2): 83-97[DOI][PubMed]
  • 11. Favre M. Structural polypeptides of rabbit, bovine, and human papillomaviruses. J Virol. 1975; 15(5): 1239-47[PubMed]
  • 12. Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 1999; 189(1): 12-9[DOI][PubMed]
  • 13. Zhao C, Yang H. Human papillomavirus DNA detection in women with normal and abnormal cervical Pap cytology. Diagnostic Histopathol. 2012; 18(8): 341-7[DOI]
  • 14. Munoz N, Bosch FX, de Sanjose S, Herrero R, Castellsague X, Shah KV, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med. 2003; 348(6): 518-27[DOI][PubMed]
  • 15. Wang R, Guo XL, Wisman GB, Schuuring E, Wang WF, Zeng ZY, et al. Nationwide prevalence of human papillomavirus infection and viral genotype distribution in 37 cities in China. BMC Infect Dis. 2015; 15: 257[DOI][PubMed]
  • 16. Salehi-Vaziri M, Sadeghi F, Bokharaei-Salim F, Younesi S, Alinaghi S, Monavari SH, et al. The Prevalence and Genotype Distribution of Human Papillomavirus in the Genital Tract of Males in Iran. Jundishapur J Microbiol. 2015; 8(12): 21912[DOI][PubMed]
  • 17. Burd EM. Human papillomavirus and cervical cancer. Clin Microbiol Rev. 2003; 16(1): 1-17[PubMed]
  • 18. Munoz N, Castellsague X, de Gonzalez AB, Gissmann L. Chapter 1: HPV in the etiology of human cancer. Vaccine. 2006; 24 Suppl 3-10[DOI][PubMed]
  • 19. Munoz N. Human papillomavirus and cancer: the epidemiological evidence. J Clin Virol. 2000; 19(1-2): 1-5[PubMed]
  • 20. Haghshenas M, Golini-Moghaddam T, Rafiei A, Emadeian O, Shykhpour A, Ashrafi GH. Prevalence and type distribution of high-risk human papillomavirus in patients with cervical cancer: a population-based study. Infect Agent Cancer. 2013; 8(1): 20[DOI][PubMed]
  • 21. Souho T, El Fatemi H, Karim S, El Rhazi K, Bouchikhi C, Banani A, et al. Distribution of Carcinogenic Human Papillomavirus Genotypes and Association to Cervical Lesions among Women in Fez (Morocco). PLoS One. 2016; 11(1): 146246[DOI][PubMed]
  • 22. Zoa Assoumou S, Ndjoyi Mbiguino A, Mabika Mabika B, Nguizi Ogoula S, El Mzibri M, Khattabi A, et al. Human papillomavirus genotypes distribution among Gabonese women with normal cytology and cervical abnormalities. Infect Agent Cancer. 2016; 11: 2[DOI][PubMed]
  • 23. Munoz N, Bosch FX, de Sanjose S, Tafur L, Izarzugaza I, Gili M, et al. The causal link between human papillomavirus and invasive cervical cancer: a population-based case-control study in Colombia and Spain. Int J Cancer. 1992; 52(5): 743-9[PubMed]
  • 24. Munoz N, Bosch FX. Cervical cancer and human papillomavirus: epidemiological evidence and perspectives for prevention. Salud Publica Mex. 1997; 39(4): 274-82[PubMed]
  • 25. Wallin KL, Wiklund F, Angstrom T, Bergman F, Stendahl U, Wadell G, et al. Type-specific persistence of human papillomavirus DNA before the development of invasive cervical cancer. N Engl J Med. 1999; 341(22): 1633-8[DOI][PubMed]
  • 26. Bosch FX, Lorincz A, Munoz N, Meijer CJ, Shah KV. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol. 2002; 55(4): 244-65[PubMed]
  • 27. zur Hausen H. Papillomavirus infections--a major cause of human cancers. Biochim Biophys Acta. 1996; 1288(2)-78[PubMed]
  • 28. zur Hausen H. Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst. 2000; 92(9): 690-8[PubMed]
  • 29. Parkin DM. The global health burden of infection-associated cancers in the year 2002. Int J Cancer. 2006; 118(12): 3030-44[DOI][PubMed]
  • 30. Yuce K, Pinar A, Salman MC, Alp A, Sayal B, Dogan S, et al. Detection and genotyping of cervical HPV with simultaneous cervical cytology in Turkish women: a hospital-based study. Arch Gynecol Obstet. 2012; 286(1): 203-8[DOI][PubMed]
  • 31. Turkish cervical cancer and cervical cytology research group. Prevalence of cervical cytological abnormalities in Turkey. Int J Gynaecol Obstet. 2009; 106: 206-9[DOI]
  • 32. Kolawole O, Ogah J, Alabi O, Suleiman M, Amuda O, Kolawole F. Utilization of human papillomavirus DNA detection for cervical cancer screening in women presenting with abnormal cytology in Lokoja, Nigeria. Jundishapur J Microbiol. 2015; 8(10)[DOI]
  • 33. Bruni L, Diaz M, Castellsague X, Ferrer E, Bosch FX, de Sanjose S. Cervical human papillomavirus prevalence in 5 continents: meta-analysis of 1 million women with normal cytological findings. J Infect Dis. 2010; 202(12): 1789-99[DOI][PubMed]
  • 34. Dursun P, Senger SS, Arslan H, Kuscu E, Ayhan A. Human papillomavirus (HPV) prevalence and types among Turkish women at a gynecology outpatient unit. BMC Infect Dis. 2009; 9: 191[DOI][PubMed]
  • 35. de Sanjose S, Diaz M, Castellsague X, Clifford G, Bruni L, Munoz N, et al. Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis. Lancet Infect Dis. 2007; 7(7): 453-9[DOI][PubMed]
  • 36. Levi JE, Fernandes S, Tateno AF, Motta E, Lima LP, Eluf-Neto J, et al. Presence of multiple human papillomavirus types in cervical samples from HIV-infected women. Gynecol Oncol. 2004; 92(1): 225-31[PubMed]
  • 37. Bao YP, Li N, Smith JS, Qiao YL, Accpab members . Human papillomavirus type distribution in women from Asia: a meta-analysis. Int J Gynecol Cancer. 2008; 18(1): 71-9[DOI][PubMed]
  • 38. Brink AA, Snijders PJ, Meijer CJ. HPV detection methods. Dis Markers. 2007; 23(4): 273-81[PubMed]
  • 39. Lie AK, Kristensen G. Human papillomavirus E6/E7 mRNA testing as a predictive marker for cervical carcinoma. Expert Rev Mol Diagn. 2008; 8(4): 405-15[DOI][PubMed]
  • 40. Mayrand MH, Duarte-Franco E, Rodrigues I, Walter SD, Hanley J, Ferenczy A, et al. Human papillomavirus DNA versus Papanicolaou screening tests for cervical cancer. N Engl J Med. 2007; 357(16): 1579-88[DOI][PubMed]
  • 41. Garcia Muentes GD, Garcia Rodriguez LK, Burgos Galarraga RI, Almeida Carpio F, Ruiz Cabezas JC. Genotypes distribution of human papillomavirus in cervical samples of Ecuadorian women. Rev Bras Epidemiol. 2016; 19(1): 160-6[DOI][PubMed]
  • 42. Eghbali SS, Amirinejad R, Obeidi N, Mosadeghzadeh S, Vahdat K, Azizi F, et al. Oncogenic human papillomavirus genital infection in southern Iranian women: population-based study versus clinic-based data. Virol J. 2012; 9: 194[DOI][PubMed]
  • 43. Vaccarella S, Herrero R, Snijders PJ, Dai M, Thomas JO, Hieu NT, et al. Smoking and human papillomavirus infection: pooled analysis of the International Agency for Research on Cancer HPV Prevalence Surveys. Int J Epidemiol. 2008; 37(3): 536-46[DOI][PubMed]
  • 44. Syrjanen K, Shabalova I, Petrovichev N, Kozachenko V, Zakharova T, Pajanidi J, et al. Smoking is an independent risk factor for oncogenic human papillomavirus (HPV) infections but not for high-grade CIN. Eur J Epidemiol. 2007; 22(10): 723-35[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments