Jundishapur Journal of Microbiology

Published by: Kowsar

The Prevalence of SEN Virus and Occult Hepatitis B (OBI) Virus Infection Among Blood Donors in Ahvaz City

Samaneh Abbasi 1 , 2 , Manoochehr Makvandi 1 , 2 , * , Gharib Karimi 3 and Niloofar Neisi 2
Authors Information
1 Health Research Institute, Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Department of Virology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Iranian Blood Transfusion Organization (IBTO), Tehran, IR Iran
Article information
  • Jundishapur Journal of Microbiology: July 01, 2016, 9 (7); e37329
  • Published Online: July 3, 2016
  • Article Type: Research Article
  • Received: February 23, 2016
  • Revised: May 31, 2016
  • Accepted: June 21, 2016
  • DOI: 10.5812/jjm.37329

To Cite: Abbasi S, Makvandi M, Karimi G, Neisi N. The Prevalence of SEN Virus and Occult Hepatitis B (OBI) Virus Infection Among Blood Donors in Ahvaz City, Jundishapur J Microbiol. 2016 ; 9(7):e37329. doi: 10.5812/jjm.37329.

Copyright © 2016, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Primi D, Fiordalisi G, Mantero GL, Mattioli S, Sottini A, Bonelli F, et al. Identification of SENV genotypes. 2000;
  • 2. Akiba J, Umemura T, Alter HJ, Kojiro M, Tabor E. SEN virus: epidemiology and characteristics of a transfusion-transmitted virus. Transfusion. 2005; 45(7): 1084-8[DOI][PubMed]
  • 3. Dehkordi P, Doosti A. The prevalence of SEN virus infection in blood donors and chronic hepatitis B and C patients in Chaharmahal Va Bakhtiari province. cell animal biol. 2011; 5(8): 182-6
  • 4. Kojima H, Kaita KD, Zhang M, Giulivi A, Minuk GY. Genomic analysis of a recently identified virus (SEN virus) and genotypes D and H by polymerase chain reaction. Antiviral Res. 2003; 60(1): 27-33[PubMed]
  • 5. Tang ZH, Chen XH, Yu YS, Zang GQ. Prevalence and clinical significance of SEN virus infection in patients with non A-E hepatitis and volunteer blood donors in Shanghai. World J Gastroenterol. 2008; 14(26): 4204-8[PubMed]
  • 6. Cakaloglu Y, Akyuz F, Bozaci M, Ibrisim D, Pinarbasi B, Demir K, et al. Prevalence and clinical significance of SEN-H virus in chronic hepatitis B, C and delta infections in Turkey. Turk J Gastroenterol. 2008; 19(2): 104-8[PubMed]
  • 7. Umemura T, Yeo AE, Sottini A, Moratto D, Tanaka Y, Wang RY, et al. SEN virus infection and its relationship to transfusion-associated hepatitis. Hepatology. 2001; 33(5): 1303-11[DOI][PubMed]
  • 8. Davidson F, MacDonald D, Mokili JL, Prescott LE, Graham S, Simmonds P. Early acquisition of TT virus (TTV) in an area endemic for TTV infection. J Infect Dis. 1999; 179(5): 1070-6[DOI][PubMed]
  • 9. Omar M, El-Din SS, Fam N, Diab M, Shemis M, Raafat M, et al. SEN virus infection in Egyptian patients with chronic hepatitis C and patients undergoing hemodialysis. Medscape J Med. 2008; 10(12): 290[PubMed]
  • 10. Shibata M, Wang RY, Yoshiba M, Shih JW, Alter HJ, Mitamura K. The presence of a newly identified infectious agent (SEN virus) in patients with liver diseases and in blood donors in Japan. J Infect Dis. 2001; 184(4): 400-4[DOI][PubMed]
  • 11. Yoshida H, Kato N, Shiratori Y, Shao R, Wang Y, Shiina S, et al. Weak association between SEN virus viremia and liver disease. J Clin Microbiol. 2002; 40(9): 3140-5[PubMed]
  • 12. Sugiura T, Goto K, Imamine H, Ando T, Ban K, Sugiyama K, et al. Prevalence of SEN virus among children in Japan. Virus Res. 2004; 100(2): 223-8[DOI][PubMed]
  • 13. Allain JP, Cox L. Challenges in hepatitis B detection among blood donors. Curr Opin Hematol. 2011; 18(6): 461-6[DOI][PubMed]
  • 14. Gonzalez R, Torres P, Castro E, Barbolla L, Candotti D, Koppelman M, et al. Efficacy of hepatitis B virus (HBV) DNA screening and characterization of acute and occult HBV infections among blood donors from Madrid, Spain. Transfusion. 2010; 50(1): 221-30[DOI][PubMed]
  • 15. Torbenson M, Thomas DL. Occult hepatitis B. Lancet Infect Dis. 2002; 2(8): 479-86[PubMed]
  • 16. Gerlich WH, Wagner FF, Chudy M, Harritshoj L, Lattermann A, Wienzek S, et al. HBsAg non‐reactive HBV infection in blood donors: Transmission and pathogenicity. Med Virol. 2007; 79-6
  • 17. Nna E, Mbamalu C, Ekejindu I. Occult hepatitis B viral infection among blood donors in South-Eastern Nigeria. Pathog Glob Health. 2014; 108(5): 223-8[DOI][PubMed]
  • 18. Alavian SM, Jazayeri SM. Occult Hepatitis B infection (OBI) in vaccinated groups, a metanalysis. Arch Med Laboratory Sci. 2015; 1(2)
  • 19. Pollicino T, Saitta C. Occult hepatitis B virus and hepatocellular carcinoma. World J Gastroenterol. 2014; 20(20): 5951-61[DOI][PubMed]
  • 20. Alavian SM. Ministry of Health in Iran is serious about controlling hepatitis B. Hepat Mon. 2007; 7(1): 3-5
  • 21. Malekzadeh R, Khatibian M, Rezvan H. Viral hepatitis in the world and Iran. J Irn Med Council. 1997; 15: 183-200
  • 22. Kumar GT, Kazim SN, Kumar M, Hissar S, Chauhan R, Basir SF, et al. Hepatitis B virus genotypes and hepatitis B surface antigen mutations in family contacts of hepatitis B virus infected patients with occult hepatitis B virus infection. J Gastroenterol Hepatol. 2009; 24(4): 588-98[DOI][PubMed]
  • 23. Umemura T, Tanaka E, Ostapowicz G, Brown KE, Heringlake S, Tassopoulos NC, et al. Investigation of SEN virus infection in patients with cryptogenic acute liver failure, hepatitis-associated aplastic anemia, or acute and chronic non-A-E hepatitis. J Infect Dis. 2003; 188(10): 1545-52[DOI][PubMed]
  • 24. Sharifi Z, Mahmoodian-Shooshtari M, Talebian A. The prevalence of SEN virus infection in blood donors in Iran. Arch Iran Med. 2008; 11(4): 423-6[PubMed]
  • 25. Karimi-Rastehkenari A, Bouzari M. High frequency of SEN virus infection in thalassemic patients and healthy blood donors in Iran. Virol J. 2010; 7: 1[PubMed]
  • 26. Mu SJ, Du J, Zhan LS, Wang HP, Chen R, Wang QL, et al. Prevalence of a newly identified SEN virus in China. World J Gastroenterol. 2004; 10(16): 2402-5[PubMed]
  • 27. Kobayashi N, Tanaka E, Umemura T, Matsumoto A, Iijima T, Higuchi M, et al. Clinical significance of SEN virus infection in patients on maintenance haemodialysis. Nephrol Dial Transplant. 2003; 18(2): 348-52[PubMed]
  • 28. Schroter M, Laufs R, Zollner B, Knodler B, Schafer P, Feucht HH. A novel DNA virus (SEN) among patients on maintenance hemodialysis: prevalence and clinical importance. J Clin Virol. 2003; 27(1): 69-73[PubMed]
  • 29. Kao JH, Chen W, Chen PJ, Lai MY, Chen DS. Prevalence and implication of a newly identified infectious agent (SEN virus) in Taiwan. J Infect Dis. 2002; 185(3): 389-92[DOI][PubMed]
  • 30. Pirovano S, Bellinzoni M, Matteelli A, Ballerini C, Albertini A, Imberti L. High prevalence of a variant of SENV in intravenous drug user HIV-infected patients. J Med Virol. 2002; 68(1): 18-23[DOI][PubMed]
  • 31. Tangkijvanich P, Theamboonlers A, Sriponthong M, Thong-Ngam D, Kullavanijaya P, Poovorawan Y. SEN virus infection in patients with chronic liver disease and hepatocellular carcinoma in Thailand. J Gastroenterol. 2003; 38(2): 142-8[DOI][PubMed]
  • 32. Simmonds P, Prescott LE, Logue C, Davidson F, Thomas AE, Ludlam CA. TT virus--part of the normal human flora? J Infect Dis. 1999; 180(5): 1748-50[DOI][PubMed]
  • 33. Candotti D, Allain JP. Transfusion-transmitted hepatitis B virus infection. J Hepatol. 2009; 51(4): 798-809[DOI][PubMed]
  • 34. Norder H, Hammas B, Larsen J, Skaug K, Magnius LO. Detection of HBV DNA by PCR in serum from an HBsAg negative blood donor implicated in cases of post-transfusion hepatitis B. Arch Virol Suppl. 1992; 4: 116-8[PubMed]
  • 35. Hu KQ. Occult hepatitis B virus infection and its clinical implications. J Viral Hepat. 2002; 9(4): 243-57[PubMed]
  • 36. Panigrahi R, Biswas A, Datta S, Banerjee A, Chandra PK, Mahapatra PK, et al. Anti-hepatitis B core antigen testing with detection and characterization of occult hepatitis B virus by an in-house nucleic acid testing among blood donors in Behrampur, Ganjam, Orissa in southeastern India: implications for transfusion. Virol J. 2010; 7: 204[DOI][PubMed]
  • 37. Kafi-abad SA, Rezvan H, Abolghasemi H, Talebian A. Prevalence and trends of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus among blood donors in Iran, 2004 through 2007. Transfusion. 2009; 49(10): 2214-20[DOI][PubMed]
  • 38. Garcia-Montalvo BM, Ventura-Zapata LP. Molecular and serological characterization of occult hepatitis B infection in blood donors from Mexico. Ann Hepatol. 2011; 10(2): 133-41[PubMed]
  • 39. Wang JT, Wang TH, Sheu JC, Shih LN, Lin JT, Chen DS. Detection of hepatitis B virus DNA by polymerase chain reaction in plasma of volunteer blood donors negative for hepatitis B surface antigen. J Infect Dis. 1991; 163(2): 397-9[PubMed]
  • 40. Wang D, Tan D, Cao X. [A prospective study of posttransfusion hepatitis B virus infection]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2000; 14(1): 77-9[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments