Jundishapur Journal of Microbiology

Published by: Kowsar

Molecular Diversity of Mycobacterium tuberculosis Strains in Northwestern Iran

Mahya Pourostadi 1 , Jalil Rashedi 2 , * , Behroz Mahdavi Poor 3 , 4 , Hossein Samadi Kafil 5 , Samaneh Shirazi 6 and Mohammad Asgharzadeh 7
Authors Information
1 Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran
2 Tuberculosis and Lung Disease Research Center, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, IR Iran
3 Department of Laboratory Science, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, IR Iran
4 Department of Medical Parasitology, Faculty of Medicine, Tarbiat Modares University, Tehran, IR Iran
5 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran
6 Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, IR Iran
7 Hematology-Oncology Research Center, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, IR Iran
Article information
  • Jundishapur Journal of Microbiology: September 01, 2016, 9 (9); e35520
  • Published Online: August 31, 2016
  • Article Type: Research Article
  • Received: December 15, 2015
  • Revised: July 23, 2016
  • Accepted: August 7, 2016
  • DOI: 10.5812/jjm.35520

To Cite: Pourostadi M, Rashedi J, Mahdavi Poor B, Samadi Kafil H, Shirazi S, et al. Molecular Diversity of Mycobacterium tuberculosis Strains in Northwestern Iran, Jundishapur J Microbiol. 2016 ; 9(9):e35520. doi: 10.5812/jjm.35520.

Copyright © 2016, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Global tuberculosis report 2015. 2015;
  • 2. Khosravi AD, Goodarzi H, Alavi SM, Akhond MR. Application of Deletion- Targeted Multiplex PCR technique for detection of Mycobacterium tuberculosis Beijing strains in samples from tuberculosis patients. Iran J Microbiol. 2014; 6(5): 330-4[PubMed]
  • 3. Asgharzadeh M, Khakpour M, Salehi TZ, Kafil HS. Use of mycobacterial interspersed repetitive unit-variable-number tandem repeat typing to study Mycobacterium tuberculosis isolates from East Azarbaijan province of Iran. Pak J Biol Sci. 2007; 10(21): 3769-77[PubMed]
  • 4. Borgdorff MW, Nagelkerke NJ, de Haas PE, van Soolingen D. Transmission of Mycobacterium tuberculosis depending on the age and sex of source cases. Am J Epidemiol. 2001; 154(10): 934-43[PubMed]
  • 5. Asgharzadeh M, Samadi Kafil H, Pourostadi M. Source case identification and control of tuberculosis by molecular epidemiology [in Persian]. J Mazandaran Univ Med Sci. 2014; 24(115): 181-91
  • 6. Bandera A, Gori A, Catozzi L, Degli Esposti A, Marchetti G, Molteni C, et al. Molecular epidemiology study of exogenous reinfection in an area with a low incidence of tuberculosis. J Clin Microbiol. 2001; 39(6): 2213-8[DOI][PubMed]
  • 7. Singh M, Mynak ML, Kumar L, Mathew JL, Jindal SK. Prevalence and risk factors for transmission of infection among children in household contact with adults having pulmonary tuberculosis. Arch Dis Child. 2005; 90(6): 624-8[DOI][PubMed]
  • 8. Farnia P, Mohammadi F, Masjedi MR, Varnerot A, Zarifi AZ, Tabatabee J, et al. Evaluation of tuberculosis transmission in Tehran: using RFLP and spoligotyping methods. J Infect. 2004; 49(2): 94-101[DOI][PubMed]
  • 9. Mazars E, Lesjean S, Banuls AL, Gilbert M, Vincent V, Gicquel B, et al. High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology. Proc Natl Acad Sci U S A. 2001; 98(4): 1901-6[DOI][PubMed]
  • 10. Frothingham R, Meeker-O'Connell WA. Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. Microbiology. 1998; 144 ( Pt 5): 1189-96[DOI][PubMed]
  • 11. Supply P, Mazars E, Lesjean S, Vincent V, Gicquel B, Locht C. Variable human minisatellite-like regions in the Mycobacterium tuberculosis genome. Mol Microbiol. 2000; 36(3): 762-71[PubMed]
  • 12. Blackwood KS, Wolfe JN, Kabani AM. Application of mycobacterial interspersed repetitive unit typing to Manitoba tuberculosis cases: can restriction fragment length polymorphism be forgotten? J Clin Microbiol. 2004; 42(11): 5001-6[DOI][PubMed]
  • 13. Rafi A, Moaddab SR. Principles of mycobacteriology [in Persian] 2003;
  • 14. Asgharzadeh M, Samadi Kafil H, Khakpour M. Comparison of mycobacterial interspersed repetitive unit-variable number tandem repeat and IS6110-RFLP methods in identifying epidemiological links in patients with tuberculosis in Northwest of Iran. Ann Microbiol. 2008; 58(2): 333-9[DOI]
  • 15. Kam KM, Yip CW, Tse LW, Leung KL, Wong KL, Ko WM, et al. Optimization of variable number tandem repeat typing set for differentiating Mycobacterium tuberculosis strains in the Beijing family. FEMS Microbiol Lett. 2006; 256(2): 258-65[DOI][PubMed]
  • 16. Hunter PR, Gaston MA. Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. J Clin Microbiol. 1988; 26(11): 2465-6[PubMed]
  • 17. Asgharzadeh M, Kafil HS, Roudsary AA, Hanifi GR. Tuberculosis transmission in Northwest of Iran: using MIRU-VNTR, ETR-VNTR and IS6110-RFLP methods. Infect Genet Evol. 2011; 11(1): 124-31[DOI][PubMed]
  • 18. Tazi L, Reintjes R, Banuls AL. Tuberculosis transmission in a high incidence area: a retrospective molecular epidemiological study of Mycobacterium tuberculosis in Casablanca, Morocco. Infect Genet Evol. 2007; 7(5): 636-44[DOI][PubMed]
  • 19. Rashedi J, Mahdavi Poor B, Rafi A, Asgharzadeh M, Abdolalizadeh J, Moaddab SR. Multidrug-resistant tuberculosis in north-west of Iran and Republic of Azerbaijan: a major public health concern for Iranian people. J Res Health Sci. 2015; 15(2): 101-3[PubMed]
  • 20. Asgharzadeh M, Shahbabian K, Samadi Kafil H, Rafi A. Use of DNA Fingerprinting in Identifying the Source Case of Tuberculosis in East Azarbaijan Province of Iran. J Med Sci. 2007; 7(3): 418-21[DOI]
  • 21. Zamani S, Aflaki M, Fooladi AA, Darban-Sarokhalil D, Bameri Z, Khazaee S, et al. MIRU-VNTR analysis of the Mycobacterium tuberculosis isolates from three provinces of Iran. Scand J Infect Dis. 2013; 45(2): 124-30[DOI][PubMed]
  • 22. Vatani S, Khosravi AD, Feizabadi MM, Jolodar A. Study of genetic diversity in Mycobacterium tuberculosis by using mycobacterial interspersed repetitive unit: Variable number tandem repeat typing in Khuzestan Province, Iran. Afr J Microbiol Res. 2011; 5(12): 1549-56[DOI]
  • 23. Liu RX, Li QZ, Xing LL, Peng Z, Zhu CM, Yang ZH. Genotyping of clinical Mycobacterium tuberculosis isolates based on eight loci of MIRU-VNTR. Int J Tuberc Lung Dis. 2013; 17(2): 243-5[DOI][PubMed]
  • 24. Chin PJ, Jou R. A modified automated high-throughput mycobacterial interspersed repetitive unit method for genotyping Mycobacterium tuberculosis. Diagn Microbiol Infect Dis. 2005; 53(4): 325-7[DOI][PubMed]
  • 25. Sun YJ, Lee AS, Ng ST, Ravindran S, Kremer K, Bellamy R, et al. Characterization of ancestral Mycobacterium tuberculosis by multiple genetic markers and proposal of genotyping strategy. J Clin Microbiol. 2004; 42(11): 5058-64[DOI][PubMed]
  • 26. Nikolayevskyy V, Gopaul K, Balabanova Y, Brown T, Fedorin I, Drobniewski F. Differentiation of tuberculosis strains in a population with mainly Beijing-family strains. Emerg Infect Dis. 2006; 12(9): 1406-13[DOI][PubMed]
  • 27. Kam KM, Yip CW, Tse LW, Wong KL, Lam TK, Kremer K, et al. Utility of mycobacterial interspersed repetitive unit typing for differentiating multidrug-resistant Mycobacterium tuberculosis isolates of the Beijing family. J Clin Microbiol. 2005; 43(1): 306-13[DOI][PubMed]
  • 28. Uzoewulu GN, Lawson L, Nnanna IS, Rastogi N, Goyal M. Genetic diversity of Mycobacterium tuberculosis complex strains isolated from patients with pulmonary tuberculosis in Anambra State, Nigeria. Int J Mycobacteriol. 2016; 5(1): 74-9[DOI][PubMed]
  • 29. Jonsson J, Hoffner S, Berggren I, Bruchfeld J, Ghebremichael S, Pennhag A, et al. Comparison between RFLP and MIRU-VNTR genotyping of Mycobacterium tuberculosis strains isolated in Stockholm 2009 to 2011. PLoS One. 2014; 9(4): 95159[DOI][PubMed]
  • 30. Allix-Beguec C, Fauville-Dufaux M, Supply P. Three-year population-based evaluation of standardized mycobacterial interspersed repetitive-unit-variable-number tandem-repeat typing of Mycobacterium tuberculosis. J Clin Microbiol. 2008; 46(4): 1398-406[DOI][PubMed]
  • 31. Braden CR, Templeton GL, Cave MD, Valway S, Onorato IM, Castro KG, et al. Interpretation of restriction fragment length polymorphism analysis of Mycobacterium tuberculosis isolates from a state with a large rural population. J Infect Dis. 1997; 175(6): 1446-52[PubMed]
  • 32. Golub JE, Cronin WA, Obasanjo OO, Coggin W, Moore K, Pope DS, et al. Transmission of Mycobacterium tuberculosis through casual contact with an infectious case. Arch Intern Med. 2001; 161(18): 2254-8[PubMed]
  • 33. Maguire H, Dale JW, McHugh TD, Butcher PD, Gillespie SH, Costetsos A, et al. Molecular epidemiology of tuberculosis in London 1995-7 showing low rate of active transmission. Thorax. 2002; 57(7): 617-22[PubMed]
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