Jundishapur Journal of Microbiology

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Prevalence of Extended-Spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Isolates in Nosocomial and Community-Acquired Urinary Tract Infections

Mohammad Latifpour 1 , Abolfazl Gholipour 1 , * and Mohammad Sadegh Damavandi 1
Authors Information
1 Department of Microbiology and Immunology, Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, IR Iran
Article information
  • Jundishapur Journal of Microbiology: March 01, 2016, 9 (3); e31179
  • Published Online: March 12, 2016
  • Article Type: Research Article
  • Received: June 30, 2015
  • Revised: December 23, 2015
  • Accepted: January 12, 2016
  • DOI: 10.5812/jjm.31179

To Cite: Latifpour M, Gholipour A, Damavandi M S. Prevalence of Extended-Spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Isolates in Nosocomial and Community-Acquired Urinary Tract Infections, Jundishapur J Microbiol. 2016 ; 9(3):e31179. doi: 10.5812/jjm.31179.

Copyright © 2016, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Das RN, Chandrashekhar TS, Joshi HS, Gurung M, Shrestha N, Shivananda PG. Frequency and susceptibility profile of pathogens causing urinary tract infections at a tertiary care hospital in western Nepal. Singapore Med J. 2006; 47(4): 281-5[PubMed]
  • 2. Eftekhar F, Rastegar M, Golalipoor M, Mansoursamaei N. Detection of Extended Spectrum B-Lactamases in Urinary Isolates of Klebsiella pneumoniae in Relation to Bla, Bla and Bla Gene Carriage. Iran J Public Health. 2012; 41(3): 127-32[PubMed]
  • 3. Shaikh S, Fatima J, Shakil S, Rizvi SM, Kamal MA. Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment. Saudi J Biol Sci. 2015; 22(1): 90-101[DOI][PubMed]
  • 4. Bradford PA. Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev. 2001; 14(4): 933-51[DOI][PubMed]
  • 5. Livermore DM. beta-Lactamases in laboratory and clinical resistance. Clin Microbiol Rev. 1995; 8(4): 557-84[PubMed]
  • 6. Gholipour A, Soleimani N, Shokri D, Mobasherizadeh S, Kardi M, Baradaran A. Phenotypic and Molecular Characterization of Extended-Spectrum beta-Lactamase Produced by Escherichia coli, and Klebsiella pneumoniae Isolates in an Educational Hospital. Jundishapur J Microbiol. 2014; 7(8)[DOI]
  • 7. Bali EB, Acik L, Sultan N. Phenotypic and molecular characterization of SHV, TEM, CTX-M and extended-spectrum beta-lactamase produced by Escherichia coli, Acinobacter baumannii and Klebsiella isolates in a Turkish hospital. Afr J Microbiol Res. 2010; 4(8): 650-4
  • 8. Kiratisin P, Apisarnthanarak A, Laesripa C, Saifon P. Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. Antimicrob Agents Chemother. 2008; 52(8): 2818-24[DOI][PubMed]
  • 9. Harada Y, Morinaga Y, Yamada K, Migiyama Y, Nagaoka K, Migiyama Y. Clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia Coli in a Japanese Tertiary Hospital. J Med Microb Diagn. 2013; 2(127): 2161-703.1000127
  • 10. Barguigua A, El Otmani F, Talmi M, Bourjilat F, Haouzane F, Zerouali K, et al. Characterization of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from the community in Morocco. J Med Microbiol. 2011; 60: 1344-52[DOI][PubMed]
  • 11. Marchandin H, Carriere C, Sirot D, Pierre HJ, Darbas H. TEM-24 produced by four different species of Enterobacteriaceae, including Providencia rettgeri, in a single patient. Antimicrob Agents Chemother. 1999; 43(8): 2069-73[PubMed]
  • 12. Coudron PE, Moland ES, Sanders CC. Occurrence and detection of extended-spectrum beta-lactamases in members of the family Enterobacteriaceae at a veterans medical center: seek and you may find. J Clin Microbiol. 1997; 35(10): 2593-7[PubMed]
  • 13. Poirel L, Menuteau O, Agoli N, Cattoen C, Nordmann P. Outbreak of extended-spectrum beta-lactamase VEB-1-producing isolates of Acinetobacter baumannii in a French hospital. J Clin Microbiol. 2003; 41(8): 3542-7[PubMed]
  • 14. Girlich D, Naas T, Leelaporn A, Poirel L, Fennewald M, Nordmann P. Nosocomial spread of the integron-located veb-1-like cassette encoding an extended-pectrum beta-lactamase in Pseudomonas aeruginosa in Thailand. Clin Infect Dis. 2002; 34(5): 603-11[DOI][PubMed]
  • 15. Jain A, Mondal R. TEM and SHV genes in extended spectrum beta-lactamase producing Klebsiella species beta their antimicrobial resistance pattern. Indian J Med Res. 2008; 128(6): 759-64[PubMed]
  • 16. CLSI . Performance standards for antimicrobial susceptibility testing: Sixteenth informational supplement. 2006; 26
  • 17. Blondeau JM, Vaughan D. A review of antimicrobial resistance in Canada. Can J Microbiol. 2000; 46(10): 867-77[PubMed]
  • 18. Aguila A, Herrera AG, Morrison D, Cosgrove B, Perojo A, Montesinos I, et al. Bacteriostatic activity of human lactoferrin againstStaphylococcus aureusis a function of its iron-binding properties and is not influenced by antibiotic resistance. FEMS Immunol Med Microbiol. 2001; 31(2): 145-52[DOI]
  • 19. Dallal MS, Sabbaghi A, Aghamirzaeie HM, Lari AR, Eshraghian MR, Mehrabad JF, et al. Prevalence of AmpC and SHV beta-lactamases in clinical isolates of Escherichia coli from Tehran Hospitals. Jundishapur J Microbiol. 2013; 6(2): 176-80[DOI]
  • 20. Irajian G, Jazayeri-Moghadas A, Beheshti A. Prevalence of extended-spectrum beta lactamase positive and multidrug resistance pattern of Escherichia coli and Klebsiella pneumoniae isolates, Semnan, Iran. Iran J Med Microbiol. 2009; 1(1): 49-53
  • 21. Feizabadi MM, Mahamadi-Yeganeh S, Mirsalehian A, Mirafshar SM, Mahboobi M, Nili F, et al. Genetic characterization of ESBL producing strains of Klebsiella pneumoniae from Tehran hospitals. J Infect Dev Ctries. 2010; 4(10): 609-15[PubMed]
  • 22. Mirsalehian A, Feizabadi M, Nakhjavani FA, Jabalameli F, Goli H, Kalantari N. Detection of VEB-1, OXA-10 and PER-1 genotypes in extended-spectrum beta-lactamase-producing Pseudomonas aeruginosa strains isolated from burn patients. Burns. 2010; 36(1): 70-4[DOI][PubMed]
  • 23. Ghafourian S, Bin Sekawi Z, Sadeghifard N, Mohebi R, Kumari Neela V, Maleki A, et al. The Prevalence of ESBLs Producing Klebsiella pneumoniae Isolates in Some Major Hospitals, Iran. Open Microbiol J. 2011; 5: 91-5[DOI][PubMed]
  • 24. Akpaka PE, Legall B, Padman J. Molecular detection and epidemiology of extended-spectrum beta-lactamase genes prevalent in clinical isolates of Klebsiella pneumoniae and E coli from Trinidad and Tobago. West Indian Med J. 2010; 59(6): 591-6[PubMed]
  • 25. Tofteland S, Haldorsen B, Dahl KH, Simonsen GS, Steinbakk M, Walsh TR, et al. Effects of phenotype and genotype on methods for detection of extended-spectrum-beta-lactamase-producing clinical isolates of Escherichia coli and Klebsiella pneumoniae in Norway. J Clin Microbiol. 2007; 45(1): 199-205[DOI][PubMed]
  • 26. Riaz B, Khatoon H. Evaluation of the use of cephalosporin antibiotics in pediatrics. Journal of Applied Pharmaceutical Science. 2013; 3(4): 63-6[DOI]
  • 27. Behzadi P, Behzadi E, Yazdanbod H, Aghapour R, Akbari Cheshmeh M, Salehian Omran D. Evaluation of the use of cephalosporin antibiotics in pediatrics. Maedica (Buchar). 2010; 5(2): 111-15[PubMed]
  • 28. Iroha IR, Adikwu MU, Esimone CO, Aibinu I, Amadi ES. Extended spectrum beta lactamase (ESBL) in E. coli isolated from a tertiary hospital in Enugu State, Nigeria. Pak J Med Sci. 2009; 25(2): 279-82
  • 29. Overdevest I, Willemsen I, Rijnsburger M, Eustace A, Xu L, Hawkey P, et al. Extended-spectrum beta-lactamase genes of Escherichia coli in chicken meat and humans, The Netherlands. Emerg Infect Dis. 2011; 17(7): 1216-22[DOI][PubMed]
  • 30. Feizabadi MM, Etemadi G, Yadegarinia D, Rahmati M, Shabanpoor S, Bokaei S. Antibiotic-resistance patterns and frequency of extended-spectrum beta-lactamase-producing isolates of Klebsiella pneumoniae in Tehran. Med Sci Monit. 2006; 12(11)-5[PubMed]
  • 31. Calbo E, Romani V, Xercavins M, Gomez L, Vidal CG, Quintana S, et al. Risk factors for community-onset urinary tract infections due to Escherichia coli harbouring extended-spectrum beta-lactamases. J Antimicrob Chemother. 2006; 57(4): 780-3[DOI][PubMed]
  • 32. Zaniani FR, Meshkat Z, Naderi Nasab M, Khaje-Karamadini M, Ghazvini K, Rezaee A, et al. The Prevalence of TEM and SHV Genes among Extended-Spectrum Beta-Lactamases Producing Escherichia Coli and Klebsiella Pneumoniae. Iran J Basic Med Sci. 2012; 15(1): 654-60[PubMed]
  • 33. Jalalpour S. Prevalence of Klebsiella pneumoniae ESBLs Producer Strains in Hospitalized and Community Acquired Urinary Tract Infections. J Res Med Sci. 2012; 14(8): 87-9
  • 34. Aminzadeh Z, Sadat Kashi M, Sha'bani M. Bacteriuria by extended-spectrum Beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: isolates in a governmental hospital in South of Tehran, Iran. Iran J Kidney Dis. 2008; 2(4): 197-200[PubMed]
  • 35. Bazzaz BS, Naderinasab M, Mohamadpoor AH, Farshadzadeh Z, Ahmadi S, Yousefi F. The prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae among clinical isolates from a general hospital in Iran. Acta Microbiol Immunol Hung. 2009; 56(1): 89-99[DOI][PubMed]
  • 36. Mobasherizadeh S. Antimicrobial resistance surveillance among hospitalized and non-hospitalized extend-spectrum beta-lactamase producing Escherichia coli from four tertiary-care hospitals in Isfahan, Iran; 2008-2011. Afr J Biotechnol. 2012; 6(5)[DOI]
  • 37. Mirsalehian A, Akbari-Nakhjavani F, Peymani A, Kazemi B, Jabal Ameli F, Mirafshar SM. Prevalence of extended spectrum beta-lactamase-producing enterobacteriaceae by phenotypic and genotypic methods in intensive care units in tehran, iran. Daru. 2008; 16(3)
  • 38. Lal P, Kapil A, Das BK, Sood S. Occurrence of TEM and SHV gene in extended spectrum beta-lactamases (ESBLs) producing Klebsiella sp. isolated from a tertiary care hospital. Indian J Med Res. 2007; 125(2): 173-8[PubMed]
  • 39. Jabeen K, Zafar A, Hasan R. Frequency and sensitivity pattern of Extended Spectrum beta Lactamase producing isolates in a tertiary care hospital laboratory of Pakistan. J Pak Med Assoc. 2005; 55(10): 436-9[PubMed]
  • 40. Shanthi M, Sekar U. Extended spectrum beta lactamase producing Escherichia coli and Klebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes. J Assoc Physicians India. 2010; 58 Suppl: 41-4[PubMed]
  • 41. Messai Y, Iabadene H, Benhassine T, Alouache S, Tazir M, Gautier V, et al. Prevalence and characterization of extended-spectrum beta-lactamases in Klebsiella pneumoniae in Algiers hospitals (Algeria). Pathol Biol (Paris). 2008; 56(5): 319-25[DOI][PubMed]
  • 42. Romero ED, Padilla TP, Hernandez AH, Grande RP, Vazquez MF, Garcia IG, et al. Prevalence of clinical isolates of Escherichia coli and Klebsiella spp. producing multiple extended-spectrum beta-lactamases. Diagn Microbiol Infect Dis. 2007; 59(4): 433-7[DOI][PubMed]
  • 43. Kuo K, Shen Y, Hwang K. Clinical implications and risk factors of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae infection in children: a case-control retrospective study in a medical center in southern Taiwan. Clin Microbiol Infect. 2007; 40(3): 248-54
  • 44. Saurina G, Quale JM, Manikal VM, Oydna E, Landman D. Antimicrobial resistance in Enterobacteriaceae in Brooklyn, NY: epidemiology and relation to antibiotic usage patterns. J Antimicrob Chemother. 2000; 45(6): 895-8[PubMed]
  • 45. Sharma J, Sharma M, Ray P. Detection of TEM and SHV genes in Escherichia coli and Klebsiella pneumoniae isolates in a tertiary care hospital from India. Indian J Med Res. 2010; 132: 332-6[PubMed]
  • 46. Khosravi AD, Hoveizavi H, Mehdinejad M. Prevalence of Klebsiella pneumoniae Encoding Genes for Ctx-M-1, Tem-1 and Shv-1 Extended-Spectrum Beta Lactamases (ESBL) Enzymes in Clinical Specimens. Jundishapur J Microbiol. 2013; 6(10)[DOI]
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