Jundishapur Journal of Microbiology

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Phylogenetic and Transcripts Profiling of Glucose Sensing Related Genes in Candida glabrata

Tzu Shan Ng 1 , Mohd Nasir Mohd Desa 2 , Doblin Sandai 3 , Pei Pei Chong 2 and Leslie Thian Lung Than 1 , *
Authors Information
1 Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
2 Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
3 Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Kepala Batas, Penang, Malaysia
Article information
  • Jundishapur Journal of Microbiology: November 01, 2015, 8 (11); e25177
  • Published Online: November 21, 2015
  • Article Type: Research Article
  • Received: November 9, 2014
  • Revised: July 17, 2015
  • Accepted: July 22, 2015
  • DOI: 10.5812/jjm.25177

To Cite: Ng T S, Mohd Desa M N, Sandai D, Chong P P, Than L T L. Phylogenetic and Transcripts Profiling of Glucose Sensing Related Genes in Candida glabrata, Jundishapur J Microbiol. 2015 ; 8(11):e25177. doi: 10.5812/jjm.25177.

Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev. 2007; 20(1): 133-63[DOI][PubMed]
  • 2. Diekema D, Arbefeville S, Boyken L, Kroeger J, Pfaller M. The changing epidemiology of healthcare-associated candidemia over three decades. Diagn Microbiol Infect Dis. 2012; 73(1): 45-8[DOI][PubMed]
  • 3. Molero G, Diez-Orejas R, Navarro-Garcia F, Monteoliva L, Pla J, Gil C, et al. Candida albicans: genetics, dimorphism and pathogenicity. Int Microbiol. 1998; 1(2): 95-106[PubMed]
  • 4. Fidel PL, Vazquez JA, Sobel JD. Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans. Clin Microbiol Rev. 1999; 12(1): 80-96[PubMed]
  • 5. Rolland F, Winderickx J, Thevelein JM. Glucose-sensing and -signalling mechanisms in yeast. FEMS Yeast Res. 2002; 2(2): 183-201[PubMed]
  • 6. Gancedo JM. The early steps of glucose signalling in yeast. FEMS Microbiol Rev. 2008; 32(4): 673-704[DOI][PubMed]
  • 7. Santangelo GM. Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 2006; 70(1): 253-82[DOI][PubMed]
  • 8. Miwa T, Takagi Y, Shinozaki M, Yun CW, Schell WA, Perfect JR, et al. Gpr1, a putative G-protein-coupled receptor, regulates morphogenesis and hypha formation in the pathogenic fungus Candida albicans. Eukaryot Cell. 2004; 3(4): 919-31[DOI][PubMed]
  • 9. Sabina J, Brown V. Glucose sensing network in Candida albicans: a sweet spot for fungal morphogenesis. Eukaryot Cell. 2009; 8(9): 1314-20[DOI][PubMed]
  • 10. Bialková A, Šubík J. Biology of the pathogenic yeastCandida glabrata. Folia Microbiologica. 2006; 51(1): 3-20[DOI]
  • 11. Barns SM, Lane DJ, Sogin ML, Bibeau C, Weisburg WG. Evolutionary relationships among pathogenic Candida species and relatives. J Bacteriol. 1991; 173(7): 2250-5[PubMed]
  • 12. Wong S, Fares MA, Zimmermann W, Butler G, Wolfe KH. Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata. Genome Biol. 2003; 4(2)[PubMed]
  • 13. Dujon B, Sherman D, Fischer G, Durrens P, Casaregola S, Lafontaine I, et al. Genome evolution in yeasts. Nature. 2004; 430(6995): 35-44[DOI][PubMed]
  • 14. Palma M, Seret ML, Baret PV. Combined phylogenetic and neighbourhood analysis of the hexose transporters and glucose sensors in yeasts. FEMS Yeast Res. 2009; 9(4): 526-34[DOI][PubMed]
  • 15. Yin Z, Wilson S, Hauser NC, Tournu H, Hoheisel JD, Brown AJ. Glucose triggers different global responses in yeast, depending on the strength of the signal, and transiently stabilizes ribosomal protein mRNAs. Mol Microbiol. 2003; 48(3): 713-24[PubMed]
  • 16. Rodaki A, Bohovych IM, Enjalbert B, Young T, Odds FC, Gow NA, et al. Glucose promotes stress resistance in the fungal pathogen Candida albicans. Mol Biol Cell. 2009; 20(22): 4845-55[DOI][PubMed]
  • 17. Fan J, Chaturvedi V, Shen SH. Identification and phylogenetic analysis of a glucose transporter gene family from the human pathogenic yeast Candida albicans. J Mol Evol. 2002; 55(3): 336-46[DOI][PubMed]
  • 18. Sievers F, Wilm A, Dineen D, Gibson TJ, Karplus K, Li W, et al. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol Syst Biol. 2011; 7: 539[DOI][PubMed]
  • 19. Goujon M, McWilliam H, Li W, Valentin F, Squizzato S, Paern J, et al. A new bioinformatics analysis tools framework at EMBL-EBI. Nucleic Acids Res. 2010; 38-9[DOI][PubMed]
  • 20. McWilliam H, Li W, Uludag M, Squizzato S, Park YM, Buso N, et al. Analysis Tool Web Services from the EMBL-EBI. Nucleic Acids Res. 2013; 41-600[DOI][PubMed]
  • 21. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol. 2011; 28(10): 2731-9[DOI][PubMed]
  • 22. Zuckerkandl E, Pauling L. Evolutionary Divergence and Convergence in Proteins. Evolv Genes Proteins. 1965; 97: 97-166[DOI]
  • 23. Felsenstein J. Confidence Limits on Phylogenies: An Approach Using the Bootstrap. Evolution. 1985; 39(4): 783[DOI]
  • 24. Sherman F. Getting started with yeast. Methods Enzymol. 2002; 350: 3-41[DOI]
  • 25. Brown V, Sexton JA, Johnston M. A glucose sensor in Candida albicans. Eukaryot Cell. 2006; 5(10): 1726-37[DOI][PubMed]
  • 26. Collart MA, Oliviero S. Preparation of yeast RNA. Curr Protoc Mol Biol. 2001; : 1-13[DOI]
  • 27. Resuehr D, Spiess AN. A real-time polymerase chain reaction-based evaluation of cDNA synthesis priming methods. Anal Biochem. 2003; 322(2): 287-91[PubMed]
  • 28. Bader O, Schwarz A, Kraneveld EA, Tangwattanachuleeporn M, Schmidt P, Jacobsen MD, et al. Gross karyotypic and phenotypic alterations among different progenies of the Candida glabrata CBS138/ATCC2001 reference strain. PLoS One. 2012; 7(12)[DOI][PubMed]
  • 29. Inglis DO, Arnaud MB, Binkley J, Shah P, Skrzypek MS, Wymore F, et al. The Candida genome database incorporates multiple Candida species: multispecies search and analysis tools with curated gene and protein information for Candida albicans and Candida glabrata. Nucleic Acids Res. 2012; 40-74[DOI][PubMed]
  • 30. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001; 29(9)[PubMed]
  • 31. Pfaffl MW, Horgan GW, Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 2002; 30(9)[PubMed]
  • 32. Ozcan S, Johnston M. Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev. 1999; 63(3): 554-69[PubMed]
  • 33. Ozcan S, Dover J, Rosenwald AG, Wolfl S, Johnston M. Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci U S A. 1996; 93(22): 12428-32[PubMed]
  • 34. Ozcan S, Dover J, Johnston M. Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J. 1998; 17(9): 2566-73[DOI][PubMed]
  • 35. Kim JH, Polish J, Johnston M. Specificity and regulation of DNA binding by the yeast glucose transporter gene repressor Rgt1. Mol Cell Biol. 2003; 23(15): 5208-16[PubMed]
  • 36. Sexton JA, Brown V, Johnston M. Regulation of sugar transport and metabolism by the Candida albicans Rgt1 transcriptional repressor. Yeast. 2007; 24(10): 847-60[DOI][PubMed]
  • 37. Sickmann A, Reinders J, Wagner Y, Joppich C, Zahedi R, Meyer HE, et al. The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A. 2003; 100(23): 13207-12[DOI][PubMed]
  • 38. Nourani A, Wesolowski-Louvel M, Delaveau T, Jacq C, Delahodde A. Multiple-drug-resistance phenomenon in the yeast Saccharomyces cerevisiae: involvement of two hexose transporters. Mol Cell Biol. 1997; 17(9): 5453-60[PubMed]
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