Jundishapur Journal of Microbiology

Published by: Kowsar

The Susceptibility Patterns of Candida Species Isolated From Urine Samples to Posaconazole and Caspofungin

Ali Zarei Mahmoudabadi 1 , 2 , * , Ali Rezaei-Matehkolaei 1 , 2 and Fataemeh Ghanavati 1
Authors Information
1 Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Health Research Institute, Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Article information
  • Jundishapur Journal of Microbiology: March 01, 2015, 8 (3); e24298
  • Published Online: March 21, 2015
  • Article Type: Research Article
  • Received: October 1, 2014
  • Revised: November 22, 2014
  • Accepted: December 5, 2014
  • DOI: 10.5812/jjm.24298

To Cite: Zarei Mahmoudabadi A, Rezaei-Matehkolaei A, Ghanavati F. The Susceptibility Patterns of Candida Species Isolated From Urine Samples to Posaconazole and Caspofungin, Jundishapur J Microbiol. 2015 ; 8(3):e24298. doi: 10.5812/jjm.24298.

Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Sobel JD, Kauffman CA, McKinsey D, Zervos M, Vazquez JA, Karchmer AW, et al. Candiduria: a randomized, double-blind study of treatment with fluconazole and placebo. The National Institute of Allergy and Infectious Diseases (NIAID) Mycoses Study Group. Clin Infect Dis. 2000; 30(1): 19-24[DOI][PubMed]
  • 2. Ahmadzadeh A, Valavi E, Shamsizadeh A, Zarei Mahmoudabadi A, Hydari M, Ahmadzadeh A. Fungal urinary tract infection in an infant with posterior urethral valves. Jundishapur J Microbiol. 2011; 4(1): 71-6
  • 3. Ozhak-Baysan B, Ogunc D, Colak D, Ongut G, Donmez L, Vural T, et al. Distribution and antifungal susceptibility of Candida species causing nosocomial candiduria. Med Mycol. 2012; 50(5): 529-32[DOI][PubMed]
  • 4. Kauffman CA, Fisher JF, Sobel JD, Newman CA. Candida urinary tract infections--diagnosis. Clin Infect Dis. 2011; 52 Suppl 6-6[DOI][PubMed]
  • 5. Singla N, Gulati N, Kaistha N, Chander J. Candida colonization in urine samples of ICU patients: determination of etiology, antifungal susceptibility testing and evaluation of associated risk factors. Mycopathologia. 2012; 174(2): 149-55[DOI][PubMed]
  • 6. Seifi Z, Azish M, Salehi Z, Zarei Mahmoudabadi A, Shamsizadeh A. Candiduria in children and susceptibility patterns of recovered Candida species to antifungal drugs in Ahvaz. J Nephropathol. 2013; 2(2): 122-8[DOI][PubMed]
  • 7. Tobudic S, Kratzer C, Lassnigg A, Graninger W, Presterl E. In vitro activity of antifungal combinations against Candida albicans biofilms. J Antimicrob Chemother. 2010; 65(2): 271-4[DOI][PubMed]
  • 8. DiDone L, Oga D, Krysan DJ. A novel assay of biofilm antifungal activity reveals that amphotericin B and caspofungin lyse Candida albicans cells in biofilms. Yeast. 2011; 28(8): 561-8[DOI][PubMed]
  • 9. Thompson GR, 3rd, Wiederhold NP, Vallor AC, Villareal NC, Lewis JS, 2nd, Patterson TF. Development of caspofungin resistance following prolonged therapy for invasive candidiasis secondary to Candida glabrata infection. Antimicrob Agents Chemother. 2008; 52(10): 3783-5[DOI][PubMed]
  • 10. Fisher JF, Sobel JD, Kauffman CA, Newman CA. Candida urinary tract infections--treatment. Clin Infect Dis. 2011; 52 Suppl 6-66[DOI][PubMed]
  • 11. Salehei Z, Seifi Z, Zarei Mahmoudabadi A. Sensitivity of Vaginal Isolates of Candida to Eight Antifungal Drugs Isolated From Ahvaz, Iran. J Microbiol. 2012; 5(4): 574-7[DOI]
  • 12. Reference method for broth dilution antifungal susceptibility testing of yeasts; Approved standard. 2008;
  • 13. Kauffman CA. Candiduria. Clin Infect Dis. 2005; 41 Suppl 6-6[DOI][PubMed]
  • 14. Zarei-Mahmoudabadi A, Zarrin M, Ghanatir F, Vazirianzadeh B. Candiduria in hospitalized patients in teaching hospitals of Ahvaz. Iran J Microbiol. 2012; 4(4): 198-203[PubMed]
  • 15. Sobel JD, Fisher JF, Kauffman CA, Newman CA. Candida urinary tract infections--epidemiology. Clin Infect Dis. 2011; 52 Suppl 6-6[DOI][PubMed]
  • 16. Bukhary ZA. Candiduria: a review of clinical significance and management. Saudi J Kidney Dis Transpl. 2008; 19(3): 350-60[PubMed]
  • 17. Jain M, Dogra V, Mishra B, Thakur A, Loomba PS, Bhargava A. Candiduria in catheterized intensive care unit patients: emerging microbiological trends. Indian J Pathol Microbiol. 2011; 54(3): 552-5[DOI][PubMed]
  • 18. Fraisse T, Crouzet J, Lachaud L, Durand A, Charachon S, Lavigne JP, et al. Candiduria in those over 85 years old: a retrospective study of 73 patients. Intern Med. 2011; 50(18): 1935-40[PubMed]
  • 19. Zarei Mahmoudabadi A, Keradmand AR, Enayatollahi N. Frequency of candiduria in inpatients and outpatients in department of Urology, Golestan Hospital, Ahvaz, Iran. Iran J Kidney Dis. 2009; 3(2): 114-5[PubMed]
  • 20. Kobayashi CC, de Fernandes OF, Miranda KC, de Sousa ED, Silva Mdo R. Candiduria in hospital patients: a study prospective. Mycopathologia. 2004; 158(1): 49-52[PubMed]
  • 21. Pasquale T, Tomada JR, Ghannoun M, Dipersio J, Bonilla H. Emergence of Candida tropicalis resistant to caspofungin. J Antimicrob Chemother. 2008; 61(1): 219[DOI][PubMed]
  • 22. Krogh-Madsen M, Arendrup MC, Heslet L, Knudsen JD. Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient. Clin Infect Dis. 2006; 42(7): 938-44[DOI][PubMed]
  • 23. Fekkar A, Dannaoui E, Meyer I, Imbert S, Brossas JY, Uzunov M, et al. Emergence of echinocandin-resistant Candida spp. in a hospital setting: a consequence of 10 years of increasing use of antifungal therapy? Eur J Clin Microbiol Infect Dis. 2014; 33(9): 1489-96[DOI][PubMed]
  • 24. Andes D, Marchillo K, Conklin R, Krishna G, Ezzet F, Cacciapuoti A, et al. Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis. Antimicrob Agents Chemother. 2004; 48(1): 137-42[PubMed]
  • 25. Cuenca-Estrella M, Gomez-Lopez A, Cuesta I, Zaragoza O, Mellado E, Rodriguez-Tudela JL, et al. Frequency of voriconazole resistance in vitro among Spanish clinical isolates of Candida spp. According to breakpoints established by the Antifungal Subcommittee of the European Committee on Antimicrobial Susceptibility Testing. Antimicrob Agents Chemother. 2011; 55(4): 1794-7[DOI][PubMed]
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