Jundishapur Journal of Microbiology

Published by: Kowsar

Molecular Detection of Class-D OXA Carbapenemase Genes in Biofilm and Non-Biofilm Forming Clinical Isolates of Acinetobacter baumannii

Omid Azizi 1 , Mohammad Reza Shakibaie 1 , 2 , * , Farzan Modarresi 1 and Fereshteh Shahcheraghi 3
Authors Information
1 Department of Microbiology and Virology, Kerman University of Medical Sciences, Kerman, IR Iran
2 Research Center for Infectious Diseases and Tropical Medicine, Kerman University of Medical Sciences, Kerman, IR Iran
3 Microbiology Research Center, Department of Bacteriology, Pasteur Institute of Iran, Tehran, IR Iran
Article information
  • Jundishapur Journal of Microbiology: January 01, 2015, 8 (1); e21042
  • Published Online: January 12, 2015
  • Article Type: Research Article
  • Received: June 11, 2014
  • Revised: November 10, 2014
  • Accepted: November 20, 2014
  • DOI: 10.5812/jjm.21042

To Cite: Azizi O, Shakibaie M R, Modarresi F, Shahcheraghi F. Molecular Detection of Class-D OXA Carbapenemase Genes in Biofilm and Non-Biofilm Forming Clinical Isolates of Acinetobacter baumannii, Jundishapur J Microbiol. 2015 ; 8(1):e21042. doi: 10.5812/jjm.21042.

Abstract
Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Cisneros JM, Rodriguez-Bano J. Nosocomial bacteremia due to Acinetobacter baumannii: epidemiology, clinical features and treatment. Clin Microbiol Infect. 2002; 8(11): 687-93[PubMed]
  • 2. Giamarellou H, Antoniadou A, Kanellakopoulou K. Acinetobacter baumannii: a universal threat to public health? Int J Antimicrob Agents. 2008; 32(2): 106-19[DOI][PubMed]
  • 3. Dijkshoorn L, Nemec A, Seifert H. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat Rev Microbiol. 2007; 5(12): 939-51[DOI][PubMed]
  • 4. Navon-Venezia S, Ben-Ami R, Carmeli Y. Update on Pseudomonas aeruginosa and Acinetobacter baumannii infections in the healthcare setting. Curr Opin Infect Dis. 2005; 18(4): 306-13[PubMed]
  • 5. Kuo HY, Chang KC, Kuo JW, Yueh HW, Liou ML. Imipenem: a potent inducer of multidrug resistance in Acinetobacter baumannii. Int J Antimicrob Agents. 2012; 39(1): 33-8[DOI][PubMed]
  • 6. Poirel L, Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect. 2006; 12(9): 826-36[DOI][PubMed]
  • 7. Sohrabi N, Farajnia S, Akhi MT, Nahaei MR, Naghili B, Peymani A, et al. Prevalence of OXA-type beta-lactamases among Acinetobacter baumannii isolates from Northwest of Iran. Microb Drug Resist. 2012; 18(4): 385-9[DOI][PubMed]
  • 8. Brown S, Amyes S. OXA (beta)-lactamases in Acinetobacter: the story so far. J Antimicrob Chemother. 2006; 57(1): 1-3[DOI][PubMed]
  • 9. Dalla-Costa LM, Coelho JM, Souza HA, Castro ME, Stier CJ, Bragagnolo KL, et al. Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. J Clin Microbiol. 2003; 41(7): 3403-6[PubMed]
  • 10. Boo TW, Walsh F, Crowley B. First report of OXA-23 carbapenemase in clinical isolates of Acinetobacter species in the Irish Republic. J Antimicrob Chemother. 2006; 58(5): 1101-2[DOI][PubMed]
  • 11. Liakopoulos A, Miriagou V, Katsifas EA, Karagouni AD, Daikos GL, Tzouvelekis LS, et al. Identification of OXA-23-producing Acinetobacter baumannii in Greece, 2010 to 2011. Euro Surveill. 2012; 17(11)[PubMed]
  • 12. Ciftci IH, Asik G, Karakece E, Oksuz L, Yagci S, Sesli Cetin E, et al. [Distribution of blaOXA genes in Acinetobacter baumannii strains: a multicenter study]. Mikrobiyol Bul. 2013; 47(4): 592-602[PubMed]
  • 13. Heritier C, Poirel L, Lambert T, Nordmann P. Contribution of acquired carbapenem-hydrolyzing oxacillinases to carbapenem resistance in Acinetobacter baumannii. Antimicrob Agents Chemother. 2005; 49(8): 3198-202[DOI][PubMed]
  • 14. Mendes RE, Bell JM, Turnidge JD, Castanheira M, Jones RN. Emergence and widespread dissemination of OXA-23, -24/40 and -58 carbapenemases among Acinetobacter spp. in Asia-Pacific nations: report from the SENTRY Surveillance Program. J Antimicrob Chemother. 2009; 63(1): 55-9[DOI][PubMed]
  • 15. Nowak P, Paluchowska P, Budak A. Distribution of blaOXA genes among carbapenem-resistant Acinetobacter baumannii nosocomial strains in Poland. New Microbiol. 2012; 35(3): 317-25[PubMed]
  • 16. Karmostaji A, Peerayeh SN, Salmanian AH. Distribution of OXA-Type Class D β-Lactamase Genes Among Nosocomial Multi Drug Resistant Acinetobacter baumanniiIsolated in Tehran Hospitals. Jundishapur J Microbiol. 2013; 6(5)
  • 17. Merkier AK, Catalano M, Ramirez MS, Quiroga C, Orman B, Ratier L, et al. Polyclonal spread of bla(OXA-23) and bla(OXA-58) in Acinetobacter baumannii isolates from Argentina. J Infect Dev Ctries. 2008; 2(3): 235-40[PubMed]
  • 18. Bouvet PJ, Grimont PA. Identification and biotyping of clinical isolates of Acinetobacter. Ann Inst Pasteur Microbiol. 1987; 138(5): 569-78[PubMed]
  • 19. Cockerill FR, Clinical Laboratory Standards Institute . Performance standards for antimicrobial susceptibility testing: twenty-second informational supplement;[... provides updated tables for... M02-A11 and M07-A9]. 2012;
  • 20. Woodford N, Ellington MJ, Coelho JM, Turton JF, Ward ME, Brown S, et al. Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents. 2006; 27(4): 351-3[DOI][PubMed]
  • 21. Stepanovic S, Vukovic D, Hola V, Di Bonaventura G, Djukic S, Cirkovic I, et al. Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci. APMIS. 2007; 115(8): 891-9[DOI][PubMed]
  • 22. Turton JF, Woodford N, Glover J, Yarde S, Kaufmann ME, Pitt TL. Identification of Acinetobacter baumannii by detection of the blaOXA-51-like carbapenemase gene intrinsic to this species. J Clin Microbiol. 2006; 44(8): 2974-6[DOI][PubMed]
  • 23. Mohajeri P, Farahani A, Feizabadi MM, Ketabi H, Abiri R, Najafi F. Antimicrobial susceptibility profiling and genomic diversity of Acinetobacter baumannii isolates: A study in western Iran. Iran J Microbiol. 2013; 5(3): 195-202[PubMed]
  • 24. de Breij A, Dijkshoorn L, Lagendijk E, van der Meer J, Koster A, Bloemberg G, et al. Do biofilm formation and interactions with human cells explain the clinical success of Acinetobacter baumannii? PLoS One. 2010; 5(5)[DOI][PubMed]
  • 25. Grosso F, Quinteira S, Poirel L, Novais A, Peixe L. Role of common blaOXA-24/OXA-40-carrying platforms and plasmids in the spread of OXA-24/OXA-40 among Acinetobacter species clinical isolates. Antimicrob Agents Chemother. 2012; 56(7): 3969-72[DOI][PubMed]
  • 26. Shacheraghi F, Shakibaie MR, Noveiri H. Molecular Identification of ESBL genes blaGES-1, blaVEB-1, blaCTX-M blaOXA-1, blaOXA-4, blaOXA-10 and blaPER-1 in Pseudomonas aeruginosa strains isolated from burn patients by PCR, RFLP and sequencing techniques. Int J Biol life Sci. 2010; 3(6): 138-42
  • 27. Shakibaie MR, Adeli S, Salehi MH. Antibiotic resistance patterns and extended-spectrum beta-lactamase production among Acinetobacter spp. isolated from an intensive care Unit of a hospital in Kerman, Iran. Antimicrob Resist Infect Control. 2012; 1(1): 1[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments