Jundishapur Journal of Microbiology

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Evaluation of the Correlation Between Childhood Asthma and Helicobacter pylori in Kashan

Tahere Khamechian 1 , Amir Hossein Movahedian 2 , Ghasem Ebrahimi Eskandari 3 , Marzieh Heidarzadeh Arani 3 , * and Abouzar Mohammadi 4
Authors Information
1 Anatomical Sciences Research Centre, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, IR Iran
2 Pediatric Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR Iran
3 Pediatric Department, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, IR Iran
4 Surgical Technology Department, Faculty of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, IR Iran
Article information
  • Jundishapur Journal of Microbiology: June 01, 2015, 8 (6); e17842
  • Published Online: June 1, 2015
  • Article Type: Research Article
  • Received: January 29, 2014
  • Revised: June 14, 2014
  • Accepted: June 26, 2014
  • DOI: 10.5812/jjm.8(6)2015.17842

To Cite: Khamechian T, Movahedian A H, Ebrahimi Eskandari G, Heidarzadeh Arani M, Mohammadi A. Evaluation of the Correlation Between Childhood Asthma and Helicobacter pylori in Kashan, Jundishapur J Microbiol. 2015 ; 8(6):e17842. doi: 10.5812/jjm.8(6)2015.17842.

Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Liu AH, Spahn JD, Leung DYM. Nelson Textbook of Pediatrics. 2012;
  • 2. Arnold IC, Dehzad N, Reuter S, Martin H, Becher B, Taube C, et al. Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells. J Clin Investigation. 2011; 121(8): 3088-93
  • 3. Chronic gastritis and Helicobacter pylori Seminars in gastrointestinal disease. : 196-202
  • 4. Vital signs: asthma prevalence, disease characteristics, and self-management education: United States, 2001-2009. Morbidity Mortality Weekly Rep. 2011; 60(17): 547
  • 5. Chen Y, Blaser MJ. Helicobacter pylori colonization is inversely associated with childhood asthma. J Infect Dis. 2008; 198(4): 553-60[DOI][PubMed]
  • 6. Cohen H. Peptic Ulcer and Helicobacter Pylori. Gastroenterol Clin North America. 2000; 29(4): 775-89
  • 7. D’Elios MM, Bernard MD. To treat or not to treatHelicobacter pylorito benefit asthma patients. Expert Rev Respir Med. 2010; 4(2): 147-50
  • 8. Eder W, Ege MJ, Von Mutius E. The asthma epidemic. N Engl J Med. 2006; 355(21): 2226-35[PubMed]
  • 9. Arram EO, Shahin DA, Sherif MM. Asthma is inversely associated with Helicobacter pylori status. Egyptian J Chest Dis Tuberc . 2012; 61(3): 41-5
  • 10. Fullerton D, Britton JR, Lewis SA, Pavord ID, McKeever TM, Fogarty AW. Helicobacter pylori and lung function, asthma, atopy and allergic disease--a population-based cross-sectional study in adults. Int J Epidemiol. 2009; 38(2): 419-26[PubMed]
  • 11. Gold DR, Wright R. Population disparities in asthma. Annu Rev Public Health. 2005; 26: 89-113[PubMed]
  • 12. Jun ZJ, Lei Y, Shimizu Y, Dobashi K, Mori M. Helicobacter pylori Seroprevalence in Patients with Mild Asthma. The Tohoku J Exp Med. 2005; 207(4): 287-91
  • 13. Kolho K, Haapaniemi A, Haahtela T, Rautelin H. Helicobacter pylori and Specific Immunoglobulin E Antibodies to Food Allergens in Children. J Pediatr Gastroenterol Nutr. 2005; 40(2): 180-3
  • 14. Kosunen TU, Aromaa A, Knekt P, Salomaa A, Rautelin H, Lohi P, et al. Helicobacter antibodies in 1973 and 1994 in the adult population of Vammala, Finland. Epidemiol Infect. 1997; 119(1): 29-34[PubMed]
  • 15. Xue FB, Xu YY, Wan Y, Pan BR, Ren J, Fan DM. Association of H. pylori infection with gastric carcinoma: a Meta analysis. World J Gastroenterol. 2001; 7(6): 801-4[PubMed]
  • 16. Peterson WL. Helicobacter pylori. Gastroenterol. 1998; 114(1): 224
  • 17. Parsonnet J, Hansen S, Rodriguez L, Gelb AB, Warnke RA, Jellum E, et al. Helicobacter pylori infection and gastric lymphoma. N Engl J Med. 1994; 330(18): 1267-71[PubMed]
  • 18. Realdi G, Dore MP, Fastame L. Extradigestive manifestations of Helicobacter pylori infection: fact and fiction. Dig Dis Sci. 1999; 44(2): 229-36[PubMed]
  • 19. Kountouras J, Boura P, Lygidakis NJ. Omeprazole and regulation of cytokine profile in Helicobacter pylori-infected patients with duodenal ulcer disease. Hepatogastroenterology. 2000; 47(35): 1301-4[PubMed]
  • 20. Negrini R, Savio A, Poiesi C, Appelmelk BJ, Buffoli F, Paterlini A, et al. Antigenic mimicry between Helicobacter pylori and gastric mucosa in the pathogenesis of body atrophic gastritis. Gastroenterology. 1996; 111(3): 655-65[PubMed]
  • 21. Strachan DP. Family size, infection and atopy: the first decade of the "hygiene hypothesis". Thorax. 2000; 55 Suppl 1-10[PubMed]
  • 22. Bloom B, Cohen RA, Freeman G. Summary health statistics for US children: National Health Interview Survey, 2009. Vital Health Statistics. 2010; 2010(247): 1-82
  • 23. Takahashi S, Nakamura E, Okabe S. Effects of cytokines, without and with Helicobacter pylori components, on mucus secretion by cultured gastric epithelial cells. Dig Dis Sci. 1998; 43(10): 2301-8[PubMed]
  • 24. Wang Y, Bi Y, Zhang L, Wang C. Is Helicobacter pylori infection associated with asthma risk? A meta-analysis based on 770 cases and 785 controls. Int J Med Sci. 2012; 9(7): 603
  • 25. Strickland DH, Judd S, Thomas JA, Larcombe AN, Sly PD, Holt PG. Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control. Mucosal Immunol . 2010; 4(1): 43-52
  • 26. Liutu M, Kalimo K, Kalimo H, Uksila J, Leino R. Mast cells and IgE-containing cells in gastric mucosa of Helicobacter pylori infected and non-infected patients with chronic urticaria. J European Acad Dermatol Venereol. 2004; 18(1): 69-72
  • 27. McCune A, Lane A, Murray L, Harvey I, Nair P, Donovan J, et al. Reduced risk of atopic disorders in adults with Helicobacter pylori infection. European J Gastroenterol Hepatol. 2003; 15(6): 637-40
  • 28. Zevit N, Balicer RD, Cohen HA, Karsh D, Niv Y, Shamir R. Inverse Association Between Helicobacter pylori and Pediatric Asthma in a High‐Prevalence Population. Helicobacter. 2012; 17(1): 30-5
  • 29. Tsang KW, Lam WK, Chan KN, Hu W, Wu A, Kwok E, et al. Helicobacter pylori sero-prevalence in asthma. Respir Med. 2000; 94(8): 756-9[DOI][PubMed]
  • 30. Jaber SM. Helicobacter pylori seropositivity in children with chronic disease in Jeddah, Saudi Arabia. Saudi J Gastroenterol. 2006; 12(1): 21
  • 31. Wang Q, Yu C, Sun Y. The Association Between Asthma and Helicobacter pylori: A Meta‐Analysis. Helicobacter. 2013; 18(1): 41-53
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