Jundishapur Journal of Microbiology

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Virulence Genes and Antimicrobial Resistance Pattern in Uropathogenic Escherichia coli Isolated From Hospitalized Patients in Kashan, Iran

Foroogh Neamati 1 , Farzaneh Firoozeh 1 , * , Mahmood Saffari 1 and Mohammad Zibaei 2
Authors Information
1 Department of Microbiology and Immunology, School of Medicine, Kashan University of Medical Sciences, Kashan, IR Iran
2 Department of Parasitology and Mycology, School of Medicine, Alborz University of Medical Sciences, Karaj, IR Iran
Article information
  • Jundishapur Journal of Microbiology: February 01, 2015, 8 (2); e17514
  • Published Online: February 7, 2015
  • Article Type: Research Article
  • Received: January 10, 2014
  • Revised: April 15, 2014
  • Accepted: April 19, 2014
  • DOI: 10.5812/jjm.17514

To Cite: Neamati F, Firoozeh F, Saffari M, Zibaei M. Virulence Genes and Antimicrobial Resistance Pattern in Uropathogenic Escherichia coli Isolated From Hospitalized Patients in Kashan, Iran, Jundishapur J Microbiol. 2015 ; 8(2):e17514. doi: 10.5812/jjm.17514.

Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Mao BH, Chang YF, Scaria J, Chang CC, Chou LW, Tien N, et al. Identification of Escherichia coli genes associated with urinary tract infections. J Clin Microbiol. 2012; 50(2): 449-56[DOI][PubMed]
  • 2. Kudinha T, Kong F, Johnson JR, Andrew SD, Anderson P, Gilbert GL. Multiplex PCR-based reverse line blot assay for simultaneous detection of 22 virulence genes in uropathogenic Escherichia coli. Appl Environ Microbiol. 2012; 78(4): 1198-202[DOI][PubMed]
  • 3. Akoachere JF, Yvonne S, Akum NH, Seraphine EN. Etiologic profile and antimicrobial susceptibility of community-acquired urinary tract infection in two Cameroonian towns. BMC Res Notes. 2012; 5: 219[DOI][PubMed]
  • 4. Brumbaugh AR, Mobley HL. Preventing urinary tract infection: progress toward an effective Escherichia coli vaccine. Expert Rev Vaccines. 2012; 11(6): 663-76[DOI][PubMed]
  • 5. Tarchouna M, Ferjani A, Ben-Selma W, Boukadida J. Distribution of uropathogenic virulence genes in Escherichia coli isolated from patients with urinary tract infection. Int J Infect Dis. 2013; 17(6)-3[DOI][PubMed]
  • 6. Qin X, Hu F, Wu S, Ye X, Zhu D, Zhang Y, et al. Comparison of adhesin genes and antimicrobial susceptibilities between uropathogenic and intestinal commensal Escherichia coli strains. PLoS One. 2013; 8(4)[DOI][PubMed]
  • 7. Ejrnaes K. Bacterial characteristics of importance for recurrent urinary tract infections caused by Escherichia coli. Dan Med Bull. 2011; 58(4)[PubMed]
  • 8. Farshad S, Ranjbar R, Japoni A, Hosseini M, Anvarinejad M, Mohammadzadegan R. Microbial susceptibility, virulence factors, and plasmid profiles of uropathogenic Escherichia coli strains isolated from children in Jahrom, Iran. Arch Iran Med. 2012; 15(5): 312-6
  • 9. Hacker J, Blum-Oehler G, Muhldorfer I, Tschape H. Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution. Mol Microbiol. 1997; 23(6): 1089-97[PubMed]
  • 10. Johnson JR, Stell AL. Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. J Infect Dis. 2000; 181(1): 261-72[DOI][PubMed]
  • 11. Oliveira FA, Paludo KS, Arend LN, Farah SM, Pedrosa FO, Souza EM, et al. Virulence characteristics and antimicrobial susceptibility of uropathogenic Escherichia coli strains. Genet Mol Res. 2011; 10(4): 4114-25[DOI][PubMed]
  • 12. Jadhav S, Hussain A, Devi S, Kumar A, Parveen S, Gandham N, et al. Virulence characteristics and genetic affinities of multiple drug resistant uropathogenic Escherichia coli from a semi urban locality in India. PLoS One. 2011; 6(3)[DOI][PubMed]
  • 13. Mellata M, Dho-Moulin M, Dozois CM, Curtiss R 3rd, Brown PK, Arne P, et al. Role of virulence factors in resistance of avian pathogenic Escherichia coli to serum and in pathogenicity. Infect Immun. 2003; 71(1): 536-40[PubMed]
  • 14. Usein CR, Damian M, Tatu-Chitoiu D, Capusa C, Fagaras R, Tudorache D, et al. Prevalence of virulence genes in Escherichia coli strains isolated from Romanian adult urinary tract infection cases. J Cell Mol Med. 2001; 5(3): 303-10[PubMed]
  • 15. Kawamura-Sato K, Yoshida R, Shibayama K, Ohta M. Virulence genes, quinolone and fluoroquinolone resistance, and phylogenetic background of uropathogenic Escherichia coli strains isolated in Japan. Jpn J Infect Dis. 2010; 63(2): 113-5[PubMed]
  • 16. Gibreel TM, Dodgson AR, Cheesbrough J, Fox AJ, Bolton FJ, Upton M. Population structure, virulence potential and antibiotic susceptibility of uropathogenic Escherichia coli from Northwest England. J Antimicrob Chemother. 2012; 67(2): 346-56[DOI][PubMed]
  • 17. Momtaz H, Karimian A, Madani M, Safarpoor Dehkordi F, Ranjbar R, Sarshar M, et al. Uropathogenic Escherichia coli in Iran: serogroup distributions, virulence factors and antimicrobial resistance properties. Ann Clin Microbiol Antimicrob. 2013; 12: 8[DOI][PubMed]
  • 18. Nam EH, Ko S, Chae JS, Hwang CY. Characterization and zoonotic potential of uropathogenic Escherichia coli isolated from dogs. J Microbiol Biotechnol. 2013; 23(3): 422-9[PubMed]
  • 19. Mahon CR, Lehman DC, Manuselis G. Textbook of Diagnostic Microbiology. 2011;
  • 20. M100-S22 Performance Standards for antimicrobial susceptibility testing 21th information supplement. 2012;
  • 21. Santo E, Macedo C, Marin JM. Virulence factors of uropathogenic Escherichia coli from a university hospital in Ribeirao Preto, Sao Paulo, Brazil. Rev Inst Med Trop Sao Paulo. 2006; 48(4): 185-8[PubMed]
  • 22. Abe CM, Salvador FA, Falsetti IN, Vieira MA, Blanco J, Blanco JE, et al. Uropathogenic Escherichia coli (UPEC) strains may carry virulence properties of diarrhoeagenic E. coli. FEMS Immunol Med Microbiol. 2008; 52(3): 397-406[DOI][PubMed]
  • 23. Navidinia M, Najar Peerayeh S, Fallah F, Bakhshi B, Adabian S, Alimehr S, et al. Distribution of the Pathogenicity Islands Markers (PAIs) in Uropathogenic E.coli Isolated from Children in Mofid Children Hospital. Arch Pediatr Infect Dis. 2013; 1(2): 75-9[DOI]
  • 24. Rezaee MA, Sheikhalizadeh V, Hasani A. Detection of integrons among multi-drug resistant (MDR) Escherichia coli strains isolated from clinical specimens in northern west of Iran. Braz J Microbiol. 2011; 42(4): 1308-13[DOI][PubMed]
  • 25. Caracciolo A, Bettinelli A, Bonato C, Isimbaldi C, Tagliabue A, Longoni L, et al. Antimicrobial resistance among Escherichia coli that cause childhood community-acquired urinary tract infections in Northern Italy. Ital J Pediatr. 2011; 37: 3[DOI][PubMed]
  • 26. Iqbal M, Patel IK, Shah SH, Ain Q, Barney N, Kiani Q, et al. Susceptibility patterns of Escherichia coli: prevalence of multidrug-resistant isolates and extended spectrum beta-lactamase phenotype. J Pak Med Assoc. 2002; 52(9): 407-11[PubMed]
  • 27. Mukherjee M, Basu S, Mukherjee SK, Majumder M. Multidrug-Resistance and Extended Spectrum Beta-Lactamase Production in Uropathogenic E. Coli which were Isolated from Hospitalized Patients in Kolkata, India. J Clin Diagn Res. 2013; 7(3): 449-53[DOI][PubMed]
  • 28. Molina-Lopez J, Aparicio-Ozores G, Ribas-Aparicio RM, Gavilanes-Parra S, Chavez-Berrocal ME, Hernandez-Castro R, et al. Drug resistance, serotypes, and phylogenetic groups among uropathogenic Escherichia coli including O25-ST131 in Mexico City. J Infect Dev Ctries. 2011; 5(12): 840-9[PubMed]
  • 29. Pignanelli S, Zaccherini P, Schiavone P, Nardi Pantoli A, Pirazzoli S, Nannini R. In vitro antimicrobial activity of several antimicrobial agents against Escherichia coli isolated from community-acquired uncomplicated urinary tract infections. Eur Rev Med Pharmacol Sci. 2013; 17(2): 206-9[PubMed]
  • 30. Arredondo-Garcia JL, Amabile-Cuevas CF. High resistance prevalence towards ampicillin, co-trimoxazole and ciprofloxacin, among uropathogenic Escherichia coli isolates in Mexico City. J Infect Dev Ctries. 2008; 2(5): 350-3[PubMed]
  • 31. Adamus-Bialek W, Zajac E, Parniewski P, Kaca W. Comparison of antibiotic resistance patterns in collections of Escherichia coli and Proteus mirabilis uropathogenic strains. Mol Biol Rep. 2013; 40(4): 3429-35[DOI][PubMed]
  • 32. Shariff VAA, Shenoy MS, Yadav T, M R. The antibiotic susceptibility patterns of uropathogenic Escherichia coli, with special reference to the fluoroquinolones. J Clin Diagn Res. 2013; 7(6): 1027-30[DOI][PubMed]
  • 33. Pobiega M, Wojkowska-Mach J, Chmielarczyk A, Romaniszyn D, Adamski P, Heczko PB, et al. Molecular characterization and drug resistance of Escherichia coli strains isolated from urine from long-term care facility residents in Cracow, Poland. Med Sci Monit. 2013; 19: 317-26[DOI][PubMed]
  • 34. Hong T, Moland ES, Abdalhamid B, Hanson ND, Wang J, Sloan C, et al. Escherichia coli: development of carbapenem resistance during therapy. Clin Infect Dis. 2005; 40(10)-6[DOI][PubMed]
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