Jundishapur Journal of Microbiology

Published by: Kowsar

The Evaluation of Four In Vitro Susceptibility Testing Methods for Colistin on Carbapenenm-Resistant Acinetobacter baumannii

Hui Li 1 , 2 , Hua Zhou 3 , Xi Li 4 , Jianfeng Wang 1 , Ying Fu 1 , Yan Jiang 1 and Yunsong Yu 1 , *
Authors Information
1 Department of Infectious Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China
2 Department of Intensive Care Unit, the third People’s Hospital of Hangzhou, Hangzhou, China
3 Department of Respiratory Diseases, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
4 Centre of Laboratory Medicine, Zhejiang Provincial People’s Hospital, Hangzhou, China
Article information
  • Jundishapur Journal of Microbiology: September 2017, 10 (9); e55956
  • Published Online: September 2, 2017
  • Article Type: Brief Report
  • Received: December 20, 2016
  • Revised: June 21, 2017
  • Accepted: July 17, 2017
  • DOI: 10.5812/jjm.55956

To Cite: Li H, Zhou H, Li X, Wang J, Fu Y, et al. The Evaluation of Four In Vitro Susceptibility Testing Methods for Colistin on Carbapenenm-Resistant Acinetobacter baumannii, Jundishapur J Microbiol. 2017 ; 10(9):e55956. doi: 10.5812/jjm.55956.

Copyright © 2017, Jundishapur Journal of Microbiology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results and Discussion
5. Conclusion
  • 1. Bassetti M, Righi E, Esposito S, Petrosillo N, Nicolini L. Drug treatment for multidrug-resistant Acinetobacter baumannii infections. Future Microbiol. 2008; 3(6): 649-60[DOI][PubMed]
  • 2. Landman D, Georgescu C, Martin DA, Quale J. Polymyxins revisited. Clin Microbiol Rev. 2008; 21(3): 449-65[DOI][PubMed]
  • 3. Vila J, Pachon J. Therapeutic options for Acinetobacter baumannii infections: an update. Expert Opin Pharmacother. 2012; 13(16): 2319-36[DOI][PubMed]
  • 4. Nation RL, Li J, Cars O, Couet W, Dudley MN, Kaye KS, et al. Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus. Lancet Infect Dis. 2015; 15(2): 225-34[DOI][PubMed]
  • 5. Moskowitz SM, Garber E, Chen Y, Clock SA, Tabibi S, Miller AK, et al. Colistin susceptibility testing: evaluation of reliability for cystic fibrosis isolates of Pseudomonas aeruginosa and Stenotrophomonas maltophilia. J Antimicrob Chemother. 2010; 65(7): 1416-23[DOI][PubMed]
  • 6. Dafopoulou K, Zarkotou O, Dimitroulia E, Hadjichristodoulou C, Gennimata V, Pournaras S, et al. Comparative Evaluation of Colistin Susceptibility Testing Methods among Carbapenem-Nonsusceptible Klebsiella pneumoniae and Acinetobacter baumannii Clinical Isolates. Antimicrob Agents Chemother. 2015; 59(8): 4625-30[DOI][PubMed]
  • 7. Lo-Ten-Foe JR, de Smet AM, Diederen BM, Kluytmans JA, van Keulen PH. Comparative evaluation of the VITEK 2, disk diffusion, etest, broth microdilution, and agar dilution susceptibility testing methods for colistin in clinical isolates, including heteroresistant Enterobacter cloacae and Acinetobacter baumannii strains. Antimicrob Agents Chemother. 2007; 51(10): 3726-30[DOI][PubMed]
  • 8. Hindler JA, Humphries RM. Colistin MIC variability by method for contemporary clinical isolates of multidrug-resistant Gram-negative bacilli. J Clin Microbiol. 2013; 51(6): 1678-84[DOI][PubMed]
  • 9. Clinical and Laboratory Standards Institute . Performance standards for antimicrobial susceptibility testing; 25th information supplement M100-S25 2015;
  • 10. EUCAST Laboratory for Antimicrobial Susceptibility Testing . Breakpoint tables for interpretation of MICs and zone diameters, version 5.0 2015;
  • 11. Moodley VM, Oliver SP, Shankland I, Elisha BG. Evaluation of five susceptibility test methods for detection of tobramycin resistance in a cluster of epidemiologically related Acinetobacter baumannii isolates. J Clin Microbiol. 2013; 51(8): 2535-40[DOI][PubMed]
  • 12. International Organization for Standardization . Clinical laboratory testing and in vitro diagnostic test systems. Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices. Part 2: evaluation of performance of antimicrobial susceptibility test devices 2007;
  • 13. Hermes DM, Pormann Pitt C, Lutz L, Teixeira AB, Ribeiro VB, Netto B, et al. Evaluation of heteroresistance to polymyxin B among carbapenem-susceptible and -resistant Pseudomonas aeruginosa. J Med Microbiol. 2013; 62: 1184-9[DOI][PubMed]
  • 14. Albur M, Noel A, Bowker K, Macgowan A. Colistin susceptibility testing: time for a review. J Antimicrob Chemother. 2014; 69(5): 1432-4[DOI][PubMed]
  • 15. Mohajeri P, Farahani A, Feizabadi MM, Norozi B. Clonal evolution multi-drug resistant Acinetobacter baumannii by pulsed-field gel electrophoresis. Indian J Med Microbiol. 2015; 33(1): 87-91[DOI][PubMed]
  • 16. Sader HS, Rhomberg PR, Flamm RK, Jones RN. Use of a surfactant (polysorbate 80) to improve MIC susceptibility testing results for polymyxin B and colistin. Diagn Microbiol Infect Dis. 2012; 74(4): 412-4[DOI][PubMed]
  • 17. Li J, Rayner CR, Nation RL, Owen RJ, Spelman D, Tan KE, et al. Heteroresistance to colistin in multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother. 2006; 50(9): 2946-50[DOI][PubMed]
  • 18. Yau W, Owen RJ, Poudyal A, Bell JM, Turnidge JD, Yu HH, et al. Colistin hetero-resistance in multidrug-resistant Acinetobacter baumannii clinical isolates from the Western Pacific region in the SENTRY antimicrobial surveillance programme. J Infect. 2009; 58(2): 138-44[DOI][PubMed]
  • 19. Cai Y, Chai D, Wang R, Liang B, Bai N. Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies. J Antimicrob Chemother. 2012; 67(7): 1607-15[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments