Jundishapur Journal of Microbiology

Published by: Kowsar

Determination of Virulence Factors in Clinical Multidrug Resistance Enterococci Isolates at Southeast of Iran

Shahram Shahraki 1 , 2 and Morteza Rabi Nezhad Mousavi 1 , 2 , *
Authors Information
1 Department of Microbiology, Zahedan University of Medical Sciences, Zahedan, IR Iran
2 Infectious Diseases and Tropical Medicine Research Center, Zahedan, IR Iran
Article information
  • Jundishapur Journal of Microbiology: May 2017, 10 (5); e45514
  • Published Online: April 24, 2017
  • Article Type: Research Article
  • Received: January 8, 2017
  • Revised: March 12, 2017
  • Accepted: March 18, 2017
  • DOI: 10.5812/jjm.45514

To Cite: Shahraki S, Rabi Nezhad Mousavi M. Determination of Virulence Factors in Clinical Multidrug Resistance Enterococci Isolates at Southeast of Iran, Jundishapur J Microbiol. 2017 ; 10(5):e45514. doi: 10.5812/jjm.45514.

Copyright © 2017, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Wang JT, Chang SC, Wang HY, Chen PC, Shiau YR, Lauderdale TL, et al. High rates of multidrug resistance in Enterococcus faecalis and E. faecium isolated from inpatients and outpatients in Taiwan. Diagn Microbiol Infect Dis. 2013; 75(4): 406-11[DOI][PubMed]
  • 2. Aslam M, Diarra MS, Checkley S, Bohaychuk V, Masson L. Characterization of antimicrobial resistance and virulence genes in Enterococcus spp. isolated from retail meats in Alberta, Canada. Int J Food Microbiol. 2012; 156(3): 222-30[DOI][PubMed]
  • 3. Sun H, Wang H, Xu Y, Jones RN, Costello AJ, Liu Y, et al. Molecular characterization of vancomycin-resistant Enterococcus spp. clinical isolates recovered from hospitalized patients among several medical institutions in China. Diagn Microbiol Infect Dis. 2012; 74(4): 399-403[DOI][PubMed]
  • 4. Moura TM, Cassenego AP, Campos FS, Ribeiro AM, Franco AC, d'Azevedo PA, et al. Detection of vanC1 gene transcription in vancomycin-susceptible Enterococcus faecalis. Mem Inst Oswaldo Cruz. 2013; 108(4): 453-6[DOI][PubMed]
  • 5. Martinez JL, Baquero F. Mutation frequencies and antibiotic resistance. Antimicrob Agents Chemother. 2000; 44(7): 1771-7[PubMed]
  • 6. Gurtler V, Grando D, Mayall BC, Wang J, Ghaly-Derias S. A novel method for simultaneous Enterococcus species identification/typing and van genotyping by high resolution melt analysis. J Microbiol Methods. 2012; 90(3): 167-81[DOI][PubMed]
  • 7. Lester CH, Frimodt-Moller N, Hammerum AM. Conjugal transfer of aminoglycoside and macrolide resistance between Enterococcus faecium isolates in the intestine of streptomycin-treated mice. FEMS Microbiol Lett. 2004; 235(2): 385-91[DOI][PubMed]
  • 8. McBride SM, Fischetti VA, Leblanc DJ, Moellering RJ, Gilmore MS. Genetic diversity among Enterococcus faecalis. PLoS One. 2007; 2(7)[DOI][PubMed]
  • 9. Sava IG, Heikens E, Huebner J. Pathogenesis and immunity in enterococcal infections. Clin Microbiol Infect. 2010; 16(6): 533-40[DOI][PubMed]
  • 10. Biemer JJ. Antimicrobial susceptibility testing by the Kirby-Bauer disc diffusion method. Ann Clin Lab Sci. 1973; 3(2): 135-40[PubMed]
  • 11. Vankerckhoven V, Van Autgaerden T, Vael C, Lammens C, Chapelle S, Rossi R, et al. Development of a multiplex PCR for the detection of asa1, gelE, cylA, esp, and hyl genes in enterococci and survey for virulence determinants among European hospital isolates of Enterococcus faecium. J Clin Microbiol. 2004; 42(10): 4473-9[DOI][PubMed]
  • 12. Baldassarri L, Creti R, Arciola CR, Montanaro L, Venditti M, Di Rosa R. Analysis of virulence factors in cases of enterococcal endocarditis. Clin Microbiol Infect. 2004; 10(11): 1006-8[DOI][PubMed]
  • 13. Biendo M, Adjide C, Castelain S, Belmekki M, Rousseau F, Slama M, et al. Molecular characterization of glycopeptide-resistant enterococci from hospitals of the picardy region (france). Int J Microbiol. 2010; 2010: 150464[DOI][PubMed]
  • 14. Strateva T, Atanasova D, Savov E, Petrova G, Mitov I. Incidence of virulence determinants in clinical Enterococcus faecalis and Enterococcus faecium isolates collected in Bulgaria. Braz J Infect Dis. 2016; 20(2): 127-33[DOI][PubMed]
  • 15. Banerjee T, Anupurba S. Prevalence of Virulence Factors and Drug Resistance in Clinical Isolates of Enterococci: A Study from North India. J Pathog. 2015; 2015: 692612[DOI][PubMed]
  • 16. Takeuchi K, Tomita H, Fujimoto S, Kudo M, Kuwano H, Ike Y. Drug resistance of Enterococcus faecium clinical isolates and the conjugative transfer of gentamicin and erythromycin resistance traits. FEMS Microbiol Lett. 2005; 243(2): 347-54[DOI][PubMed]
  • 17. Sharifi Y, Hasani A, Ghotaslou R, Varshochi M, Hasani A, Aghazadeh M, et al. Survey of Virulence Determinants among Vancomycin Resistant Enterococcus faecalis and Enterococcus faecium Isolated from Clinical Specimens of Hospitalized Patients of North west of Iran. Open Microbiol J. 2012; 6: 34-9[DOI][PubMed]
  • 18. Willems RJ, Top J, van Santen M, Robinson DA, Coque TM, Baquero F, et al. Global spread of vancomycin-resistant Enterococcus faecium from distinct nosocomial genetic complex. Emerg Infect Dis. 2005; 11(6): 821-8[DOI][PubMed]
  • 19. Hallgren A, Abednazari H, Ekdahl C, Hanberger H, Nilsson M, Samuelsson A, et al. Antimicrobial susceptibility patterns of enterococci in intensive care units in Sweden evaluated by different MIC breakpoint systems. J Antimicrob Chemother. 2001; 48(1): 53-62[PubMed]
  • 20. Creti R, Imperi M, Bertuccini L, Fabretti F, Orefici G, Di Rosa R, et al. Survey for virulence determinants among Enterococcus faecalis isolated from different sources. J Med Microbiol. 2004; 53: 13-20[DOI][PubMed]
  • 21. Coque TM, Willems R, Canton R, Del Campo R, Baquero F. High occurrence of esp among ampicillin-resistant and vancomycin-susceptible Enterococcus faecium clones from hospitalized patients. J Antimicrob Chemother. 2002; 50(6): 1035-8[PubMed]
  • 22. Sabia C, de Niederhausern S, Guerrieri E, Messi P, Anacarso I, Manicardi G, et al. Detection of bacteriocin production and virulence traits in vancomycin-resistant enterococci of different sources. J Appl Microbiol. 2008; 104(4): 970-9[DOI][PubMed]
  • 23. Medeiros AW, Pereira RI, Oliveira DV, Martins PD, d'Azevedo PA, Van der Sand S, et al. Molecular detection of virulence factors among food and clinical Enterococcus faecalis strains in South Brazil. Braz J Microbiol. 2014; 45(1): 327-32[DOI][PubMed]
  • 24. Cox CR, Coburn PS, Gilmore MS. Enterococcal cytolysin: a novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells. Curr Protein Pept Sci. 2005; 6(1): 77-84[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments