Jundishapur Journal of Microbiology

Published by: Kowsar

The Association Between Oral Lichen Planus and Hepatitis C Virus Infection; A Report From Northeast of Iran

Sina Gerayli 1 , Zahra Meshkat 2 , Alireza Pasdar 3 , 4 , Pegah Mosannen Mozafari 5 , * , Elham Banihashemi 5 , Mohammad Amin Khajavi 5 and Javid Rasekhi 5
Authors Information
1 Department of Biology, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, IR Iran
2 Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
3 Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
4 Division of Applied Medicine, Medical School, University of Aberdeen, Foresterhill, Aberdeen, UK
5 Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IR Iran
Article information
  • Jundishapur Journal of Microbiology: April 01, 2015, 8 (4); e16741
  • Published Online: April 18, 2015
  • Article Type: Research Article
  • Received: December 9, 2013
  • Revised: May 6, 2014
  • Accepted: June 24, 2014
  • DOI: 10.5812/jjm.8(4)2015.16741

To Cite: Gerayli S, Meshkat Z, Pasdar A, Mosannen Mozafari P, Banihashemi E, et al. The Association Between Oral Lichen Planus and Hepatitis C Virus Infection; A Report From Northeast of Iran, Jundishapur J Microbiol. 2015 ; 8(4):e16741. doi: 10.5812/jjm.8(4)2015.16741.

Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Patrick L. Hepatitis C: epidemiology and review of complementary/alternative medicine treatments. Altern Med Rev. 1999; 4(4): 220-38[PubMed]
  • 2. Carrozzo M, Gandolfo S. Oral diseases possibly associated with hepatitis C virus. Crit Rev Oral Biol Med. 2003; 14(2): 115-27[PubMed]
  • 3. Maticic M. Hepatitis C virus infection: the dermatological perspective. Acta Dermatovenerol Alp Pannonica Adriat. 2003; 12(1): 19-27
  • 4. Harden D, Skelton H, Smith KJ. Lichen planus associated with hepatitis C virus: no viral transcripts are found in the lichen planus, and effective therapy for hepatitis C virus does not clear lichen planus. J Am Acad Dermatol. 2003; 49(5): 847-52[DOI][PubMed]
  • 5. Lodi G, Giuliani M, Majorana A, Sardella A, Bez C, Demarosi F, et al. Lichen planus and hepatitis C virus: a multicentre study of patients with oral lesions and a systematic review. Br J Dermatol. 2004; 151(6): 1172-81[DOI][PubMed]
  • 6. Prabhu S, Pavithran K, Sobhanadevi G. Lichen planus and hepatitis c virus (HCV)--is there an association? A serological study of 65 cases. Indian J Dermatol Venereol Leprol. 2002; 68(5): 273-4[PubMed]
  • 7. Lodi G, Olsen I, Piattelli A, D'Amico E, Artese L, Porter SR. Antibodies to epithelial components in oral lichen planus (OLP) associated with hepatitis C virus (HCV) infection. J Oral Pathol Med. 1997; 26(1): 36-9[PubMed]
  • 8. Jamalidoust M, Namayandeh M, Asaei S, Aliabadi N, Ziyaeyan M. Determining hepatitis C virus genotype distribution among high-risk groups in Iran using real-time PCR. World J Gastroenterol. 2014; 20(19): 5897-902[DOI][PubMed]
  • 9. MaziarMojtabavi N, Fatemeh D, Hamid H, Roya D, FariborzMakarian R. Analysis of the related factors in hepatitis C virus infection among hemophilic patients in Isfahan, Iran. Hepat Mon. 2007; 7(2): 59-62
  • 10. Alavian SM, Jabbari H, Daryani NE. Hepatitis C Virus: The Rising Concerns and Growing Hopes, Report From the HCV Symposium, Fourth Tehran Hepatitis Congress, November 2011, Tehran, Iran. Hepat Mon. 2012; 12(7): 423
  • 11. Regezi JA, Sciubba JJ, Jordan RCK. Oral Pathology: Clinical Pathologic Correlations. 2012;
  • 12. Neville BW, Damm DD, Allen C, Bouquot JE. Oral and Maxillofacial Pathology: Pageburst Retail. 2008;
  • 13. Eisen D. The clinical features, malignant potential, and systemic associations of oral lichen planus: a study of 723 patients. J Am Acad Dermatol. 2002; 46(2): 207-14[PubMed]
  • 14. Rossi L, Colasanto S. [Clinical considerations and statistical analysis on 100 patients with oral lichen planus]. Minerva Stomatol. 2000; 49(9): 393-8[PubMed]
  • 15. Campisi G, Fedele S, Lo Russo L, Di Fede O, Arico P, Craxi A, et al. HCV infection and oral lichen planus: a weak association when HCV is endemic. J Viral Hepat. 2004; 11(5): 465-70[DOI][PubMed]
  • 16. Burket LW, Greenberg MS, Glick M, Ship JA. Burket's Oral Medicine. 2008;
  • 17. Machado AC, Sugaya NN, Migliari DA, Matthews RW. Oral lichen planus. Clinical aspects and management in fifty-two Brazilian patients. West Indian Med J. 2003; 52(3): 203-7[PubMed]
  • 18. Sugerman PB, Savage NW. Oral lichen planus: causes, diagnosis and management. Aust Dent J. 2002; 47(4): 290-7[PubMed]
  • 19. Thongprasom K, Carrozzo M, Furness S, Lodi G. Interventions for treating oral lichen planus. Cochrane Database Syst Rev. 2011; (7)[DOI][PubMed]
  • 20. Rebora A, Rongioletti F. Lichen planus and chronic active hepatitis. J Am Acad Dermatol. 1984; 10(5): 840-1[DOI]
  • 21. Rebora A, Robert E, Rongioletti F. Clinical and laboratory presentation of lichen planus patients with chronic liver disease. J Dermatol Sci. 1992; 4(1): 38-41[PubMed]
  • 22. Klanrit P, Thongprasom K, Rojanawatsirivej S, Theamboonlers A, Poovorawan Y. Hepatitis C virus infection in Thai patients with oral lichen planus. Oral Dis. 2003; 9(6): 292-7[PubMed]
  • 23. Kirtak N, Inaloz HS, Erbagci Z. The prevalence of hepatitis C virus infection in patients with lichen planus in Gaziantep region of Turkey. Eur J Epidemiol. 2000; 16(12): 1159-61[PubMed]
  • 24. Shakeri MT, Foghanian B, Nomani H, Ghayour-Mobarhan M, Nabavinia MS, Rostami S, et al. The prevalence of hepatitis B virus infection in mashhad, iran: a population-based study. Iran Red Crescent Med J. 2013; 15(3): 245-8[DOI][PubMed]
  • 25. Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology. 2013; 57(4): 1333-42[DOI][PubMed]
  • 26. Pakfetrat A, Javadzadeh-Bolouri A, Basir-Shabestari S, Falaki F. Oral Lichen Planus: a retrospective study of 420 Iranian patients. Med Oral Patol Oral Cir Bucal. 2009; 14(7)-8[PubMed]
  • 27. Jahanbani J. Prevalence of oral leukoplakia and lichen planus in 1167 Iranian textile workers. Oral Dis. 2003; 9(6): 302-4[PubMed]
  • 28. Chuang TY, Stitle L, Brashear R, Lewis C. Hepatitis C virus and lichen planus: A case-control study of 340 patients. J Am Acad Dermatol. 1999; 41(5 Pt 1): 787-9[PubMed]
  • 29. Carrozzo M, Gandolfo S, Carbone M, Colombatto P, Broccoletti R, Garzino-Demo P, et al. Hepatitis C virus infection in Italian patients with oral lichen planus: a prospective case-control study. J Oral Pathol Med. 1996; 25(10): 527-33[PubMed]
  • 30. Bagan JV, Aguirre JM, del Olmo JA, Milian A, Penarrocha M, Rodrigo JM, et al. Oral lichen planus and chronic liver disease: a clinical and morphometric study of the oral lesions in relation to transaminase elevation. Oral Surg Oral Med Oral Pathol. 1994; 78(3): 337-42[PubMed]
  • 31. Jubert C, Pawlotsky JM, Pouget F, Andre C, DeForges L, Bretagne S, et al. Lichen planus and hepatitis C virus--related chronic active hepatitis. Arch Dermatol. 1994; 130(1): 73-6[PubMed]
  • 32. Nagao Y, Sata M. Hepatitis C virus and lichen planus. J Gastroenterol Hepatol. 2004; 19(10): 1101-13[DOI][PubMed]
  • 33. Asaad T, Samdani AJ. Association of lichen planus with hepatitis C virus infection. Ann Saudi Med. 2005; 25(3): 243-6[PubMed]
  • 34. Karavelioglu D, Koytak ES, Bozkaya H, Uzunalimoglu O, Bozdayi AM, Yurdaydin C. Lichen planus and HCV infection in Turkish patients. Turk J Gastroenterol. 2004; 15(3): 133-6[PubMed]
  • 35. Mahboob A, Haroon TS, Iqbal Z, Iqbal F, Butt AK. Frequency of anti-HCV antibodies in patients with lichen planus. J Coll Physicians Surg Pak. 2003; 13(5): 248-51[PubMed]
  • 36. Garg VK, Karki BM, Agrawal S, Agarwalla A, Gupta R. A study from Nepal showing no correlation between lichen planus and hepatitis B and C viruses. J Dermatol. 2002; 29(7): 411-3[PubMed]
  • 37. Tucker SC, Coulson IH. Lichen planus is not associated with hepatitis C virus infection in patients from north west England. Acta Derm Venereol. 1999; 79(5): 378-9[PubMed]
  • 38. Ghodsi SZ, Daneshpazhooh M, Shahi M, Nikfarjam A. Lichen planus and Hepatitis C: a case-control study. BMC Dermatol. 2004; 4: 6[DOI][PubMed]
  • 39. Mignogna MD, Lo Muzio L, Favia G, Mignogna RE, Carbone R, Bucci E. Oral lichen planus and HCV infection: a clinical evaluation of 263 cases. Int J Dermatol. 1998; 37(8): 575-8[PubMed]
  • 40. Chung CH, Yang YH, Chang TT, Shieh DB, Liu SY, Shieh TY. Relationship of oral lichen planus to hepatitis C virus in southern Taiwan. Kaohsiung J Med Sci. 2004; 20(4): 151-9[DOI][PubMed]
  • 41. Rahnama Z, Esfandiarpour I, Farajzadeh S. The relationship between lichen planus and hepatitis C in dermatology outpatients in Kerman, Iran. Int J Dermatol. 2005; 44(9): 746-8[DOI][PubMed]
  • 42. Ansar A, Zamanian A, Farschian M, Sorouri R, Mobaien AR. Comparison of seropositivity of HCV between oral lichen planus and healthy control group in Hamedan province (west of Iran). Our Dermatol Online. 2011; 2(4): 181
  • 43. Luis-Montoya P, Cortes-Franco R, Vega-Memije ME. [Lichen planus and hepatitis C virus. Is there an association?]. Gac Med Mex. 2005; 141(1): 23-5[PubMed]
  • 44. Daramola OO, George AO, Ogunbiyi AO. Hepatitis C virus and lichen planus in Nigerians: any relationship? Int J Dermatol. 2002; 41(4): 217-9[PubMed]
  • 45. Carrozzo M, Uboldi de Capei M, Dametto E, Fasano ME, Arduino P, Broccoletti R, et al. Tumor necrosis factor-alpha and interferon-gamma polymorphisms contribute to susceptibility to oral lichen planus. J Invest Dermatol. 2004; 122(1): 87-94[DOI][PubMed]
  • 46. Bai J, Lin M, Zeng X, Zhang Y, Wang Z, Shen J, et al. Association of polymorphisms in the human IFN-gamma and IL-4 gene with oral lichen planus: a study in an ethnic Chinese cohort. J Interferon Cytokine Res. 2008; 28(6): 351-8[DOI][PubMed]
  • 47. Carrozzo M, Francia Di Celle P, Gandolfo S, Carbone M, Conrotto D, Fasano ME, et al. Increased frequency of HLA-DR6 allele in Italian patients with hepatitis C virus-associated oral lichen planus. Br J Dermatol. 2001; 144(4): 803-8[PubMed]
  • 48. Carrozzo M, Brancatello F, Dametto E, Arduino P, Pentenero M, Rendine S, et al. Hepatitis C virus-associated oral lichen planus: is the geographical heterogeneity related to HLA-DR6? J Oral Pathol Med. 2005; 34(4): 204-8[DOI][PubMed]
  • 49. Chainani-Wu N, Lozada-Nur F, Terrault N. Hepatitis C virus and lichen planus: a review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004; 98(2): 171-83[DOI]
  • 50. Tanei R, Watanabe K, Nishiyama S. Clinical and histopathologic analysis of the relationship between lichen planus and chronic hepatitis C. J Dermatol. 1995; 22(5): 316-23[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments