Jundishapur Journal of Microbiology

Published by: Kowsar

Prevalence of Extended-Spectrum and Metallo β-Lactamase Production in AmpC β-Lactamase Producing Pseudomonas Aeruginosa Isolates From Burns

Roya Rafiee 1 , Fereshteh Eftekhar 1 , * , Seyyed Ahmad Tabatabaei 2 and Dariush Minaee Tehrani 1
Authors Information
1 Department of Microbiology, Faculty of Biological Sciences, Shahid Beheshti University, Tehran, IR Iran
2 Department of Pediatrics, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Article information
  • Jundishapur Journal of Microbiology: September 01, 2014, 7 (9); e16436
  • Published Online: September 1, 2014
  • Article Type: Research Article
  • Revised: June 9, 2014
  • Accepted: June 21, 2014
  • DOI: 10.5812/jjm.16436

To Cite: Rafiee R, Eftekhar F, Tabatabaei S A, Minaee Tehrani D. Prevalence of Extended-Spectrum and Metallo β-Lactamase Production in AmpC β-Lactamase Producing Pseudomonas Aeruginosa Isolates From Burns, Jundishapur J Microbiol. 2014 ; 7(9):e16436. doi: 10.5812/jjm.16436.

Copyright © 2014, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Fluit AC, Verhoef J, Schmitz FJ. Antimicrobial resistance in European isolates of Pseudomonas aeruginosa. European SENTRY Participants. Eur J Clin Microbiol Infect Dis. 2000; 19(5): 370-4[PubMed]
  • 2. Lister PD, Wolter DJ, Hanson ND. Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin Microbiol Rev. 2009; 22(4): 582-610[DOI][PubMed]
  • 3. Selim S, El Alfy S, Al Ruwaili M, Abdo A, Al Jaouni S. Susceptibility of imipenem-resistant Pseudomonas aeruginosa to flavonoid glycosides of date palm (Phoenix dactylifera L.) tamar growing in Al Madinah, Saudi Arabia. Afr J Biotechnol. 2012; 11(2): 416-22
  • 4. Coetzee E, Rode H, Kahn D. Pseudomonas aeruginosa burn wound infection in a dedicated paediatric burns unit. S Afr J Surg. 2013; 51(2): 50-3[DOI][PubMed]
  • 5. Livermore DM. Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clin Infect Dis. 2002; 34(5): 634-40[DOI][PubMed]
  • 6. Bush K, Jacoby GA, Medeiros AA. A functional classification scheme for beta-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother. 1995; 39(6): 1211-33[PubMed]
  • 7. Paterson DL, Bonomo RA. Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev. 2005; 18(4): 657-86[DOI][PubMed]
  • 8. Zhao WH, Hu ZQ. Beta-lactamases identified in clinical isolates of Pseudomonas aeruginosa. Crit Rev Microbiol. 2010; 36(3): 245-58[DOI][PubMed]
  • 9. Jacoby GA. AmpC beta-lactamases. Clin Microbiol Rev. 2009; 22(1): 161-82[DOI][PubMed]
  • 10. Weldhagen GF, Poirel L, Nordmann P. Ambler class A extended-spectrum beta-lactamases in Pseudomonas aeruginosa: novel developments and clinical impact. Antimicrob Agents Chemother. 2003; 47(8): 2385-92[PubMed]
  • 11. Rodriguez-Martinez JM, Poirel L, Nordmann P. Extended-spectrum cephalosporinases in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2009; 53(5): 1766-71[DOI][PubMed]
  • 12. Salimi F, Eftekhar F. Coexistence of AmpC and extendedspectrum β-lactamases in metallo-β-lactamase producing Pseudomonas aeruginosa burn isolates in Tehran. Jundishapour J Microbiol. 2013; 6(8)
  • 13. Cockerill FR. Performance standards for antimicrobial susceptibility testing: twenty-second informational supplement;[... provides updated tables for... M02-A11 and M07-A9]. 2012;
  • 14. Singhal S, Mathur T, Khan S, Upadhyay DJ, Chugh S, Gaind R, et al. Evaluation of methods for AmpC beta-lactamase in Gram negative clinical isolates from tertiary care hospitals. Indian J Med Microbiol. 2005; 23(2): 120-4[PubMed]
  • 15. Manchanda V, Singh NP. Occurrence and detection of AmpC beta-lactamases among Gram-negative clinical isolates using a modified three-dimensional test at Guru Tegh Bahadur Hospital, Delhi, India. J Antimicrob Chemother. 2003; 51(2): 415-8[PubMed]
  • 16. Lin SP, Liu MF, Lin CF, Shi ZY. Phenotypic detection and polymerase chain reaction screening of extended-spectrum beta-lactamases produced by Pseudomonas aeruginosa isolates. J Microbiol Immunol Infect. 2012; 45(3): 200-7[DOI][PubMed]
  • 17. Upadhyay S, Sen MR, Bhattacharjee A. Presence of different beta-lactamase classes among clinical isolates of Pseudomonas aeruginosa expressing AmpC beta-lactamase enzyme. J Infect Dev Ctries. 2010; 4(4): 239-42[PubMed]
  • 18. Prevalence of plasmid-mediated AmpC β-lactamases in Klebsiella pneumoniae (KP), Klebsiella oxytoca (KO), Proteus mirabilis (PM), and Salmonella (S) isolates from 42 ICU and 21 non-ICU sites in the United States. Interscience Conference on Antimicrobial Agents and Chemotherapy (ICCAC).
  • 19. Black JA, Moland ES, Thomson KS. AmpC disk test for detection of plasmid-mediated AmpC beta-lactamases in Enterobacteriaceae lacking chromosomal AmpC beta-lactamases. J Clin Microbiol. 2005; 43(7): 3110-3[DOI][PubMed]
  • 20. Basak S, Khodke M, Bose S, Mallick SK. Inducible Amp C beta-lactamase producing Pseudomonas aeruginosa isolated in a rural hospital of central India. J Clin Diagn Res. 2009; 3: 19-7
  • 21. Shahid M, Malik A, Agrawal M, Singhal S. Phenotypic detection of extended-spectrum and AmpC beta-lactamases by a new spot-inoculation method and modified three-dimensional extract test: comparison with the conventional three-dimensional extract test. J Antimicrob Chemother. 2004; 54(3): 684-7[DOI][PubMed]
  • 22. Kumar V, Sen MR, Nigam C, Gahlot R, Kumari S. Burden of different beta-lactamase classes among clinical isolates of AmpC-producing Pseudomonas aeruginosa in burn patients: A prospective study. Indian J Crit Care Med. 2012; 16(3): 136-40[DOI][PubMed]
  • 23. Sreeshma P, Champa H, Sunil RP, Subbannayya K. Detection of extended spectrum β-lactamase, AmpC β-lactamase and metallo β-lactamase in clinical isolates of Pseudomonas aeruginosa. J Pharm Biomed Sci. 2013; 33(33): 1506-15
  • 24. Fazeli H, Sadighian H, Esfahani BN, Pourmand MR. Identification of class-1 integron and various β-lactamase classes among clinical isolates of Pseudomonas aeruginosa at children's medical center hospital. J Med Bacteriol. 2012; 1(2): 25-36
  • 25. Laghawe A, Jaitly N, Thombare V. The Simultaneous Detection of the ESBL and the AmpC β-Lactamases in Gram Negative Bacilli. J Clin Diag Res. 2012; 6(4suppl2): 660-3
  • 26. Thomson KS. Controversies about extended-spectrum and AmpC beta-lactamases. Emerg Infect Dis. 2001; 7(2): 333-6[DOI][PubMed]
  • 27. Glupczynski Y, Bogaerts P, Deplano A, Berhin C, Huang TD, Van Eldere J, et al. Detection and characterization of class A extended-spectrum-beta-lactamase-producing Pseudomonas aeruginosa isolates in Belgian hospitals. J Antimicrob Chemother. 2010; 65(5): 866-71[DOI][PubMed]
  • 28. Imani Foloodi AA, Rostami Z, Shapouri R. Antimicrobial resistance and ESBL prevalence in Pseudomonas aeruginosa strains isolated from clinical specimen by phenotypic and genotypic methods. J Ardabil Univ Med Sci. 2010; 10(37): 189-98
  • 29. Jabalameli F, Mirsalehian A, Sotoudeh N, Jabalameli L, Aligholi M, Khoramian B, et al. Multiple-locus variable number of tandem repeats (VNTR) fingerprinting (MLVF) and antibacterial resistance profiles of extended spectrum beta lactamase (ESBL) producing Pseudomonas aeruginosa among burnt patients in Tehran. Burns. 2011; 37(7): 1202-7[DOI][PubMed]
  • 30. Shacheraghi F, Shakibaie MR, Noveiri H. Molecular Identification of ESBL genes blaGES-1, blaVEB-1, blaCTX-M blaOXA-1, blaOXA-4, blaOXA-10 and blaPER-1 in Pseudomonas aeruginosa strains isolated from burn patients by PCR, RFLP and sequencing techniques. Int J Biol life Sci. 2010; 3(6): 138-42
  • 31. Shahcheraghi F, Nikbin VS, Feizabadi MM. Prevalence of ESBLs genes among multidrug-resistant isolates of Pseudomonas aeruginosa isolated from patients in Tehran. Microb Drug Resist. 2009; 15(1): 37-9[DOI][PubMed]
  • 32. Zaranza AV, Morais FC, do Carmo MS, de Mendonça Marques A, Andrade-Monteiro C, Ferro TF, et al. Antimicrobial Susceptibility, Biofilm Production and Adhesion to HEp-2 Cells of Pseudomonas aeruginosa Strains Isolated from Clinical Samples. J Biomat Nanobiotechnol. 2013; 4(1): 98-106
  • 33. Bush K. Carbapenemases: Partners in crime. J Glob Antimicrob Res. 2013; 1(1): 7-16
  • 34. Livermore DM, Woodford N. Carbapenemases: a problem in waiting? Curr Opin Microbiol. 2000; 3(5): 489-95[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments