Jundishapur Journal of Microbiology

Published by: Kowsar

Possible Relations Between Epstein-Barr Virus Past Infection and Classic Multiple Sclerosis in Guilan, Iran

Hamidreza Honarmand 1 , Masoumeh Ahmadi Jalali Moghadam 2 , * , Hamidreza Hatamian 3 and Ali Roudbary 3
Authors Information
1 Department of Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, IR Iran
2 Cellular and Molecular Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, IR Iran
3 Department of Neurology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, IR Iran
Article information
  • Jundishapur Journal of Microbiology: June 01, 2015, 8 (6); e15985
  • Published Online: June 27, 2015
  • Article Type: Research Article
  • Received: November 6, 2013
  • Revised: June 1, 2014
  • Accepted: June 8, 2014
  • DOI: 10.5812/jjm.15985v2

To Cite: Honarmand H, Ahmadi Jalali Moghadam M, Hatamian H, Roudbary A. Possible Relations Between Epstein-Barr Virus Past Infection and Classic Multiple Sclerosis in Guilan, Iran, Jundishapur J Microbiol. 2015 ; 8(6):e15985. doi: 10.5812/jjm.15985v2.

Abstract
Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Pohl D. Epstein-Barr virus and multiple sclerosis. J Neurol Sci. 2009; 286(1-2): 62-4[DOI][PubMed]
  • 2. Cohen JI. Epstein-Barr virus infection. N Engl J Med. 2000; 343(7): 481-92[DOI][PubMed]
  • 3. Christensen T. The role of EBV in MS pathogenesis. Int MS J. 2006; 13(2): 52-7[PubMed]
  • 4. Ascherio A, Munch M. Epstein-Barr Virus and Multiple Sclerosis. Epidemiol. 2000; 11(2): 220-4[DOI]
  • 5. Bagert BA. Epstein-barr virus in multiple sclerosis. Curr Neurol Neurosci Rep. 2009; 9(5): 405-10[DOI]
  • 6. Ascherio A, Munger KL, Lennette ET, Spiegelman D, Hernán MA, Olek MJ, et al. Epstein-Barr Virus Antibodies and Risk of Multiple Sclerosis. JAMA. 2001; 286(24): 3083[DOI]
  • 7. Levin LI, Munger KL, Rubertone MV, Peck CA, Lennette ET, Spiegelman D, et al. Multiple sclerosis and Epstein-Barr virus. JAMA. 2003; 289(12): 1533-6[DOI][PubMed]
  • 8. Farrell RA, Antony D, Wall GR, Clark DA, Fisniku L, Swanton J, et al. Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI. Neurology. 2009; 73(1): 32-8[DOI][PubMed]
  • 9. Lunemann JD, Edwards N, Muraro PA, Hayashi S, Cohen JI, Munz C, et al. Increased frequency and broadened specificity of latent EBV nuclear antigen-1-specific T cells in multiple sclerosis. Brain. 2006; 129: 1493-506[DOI][PubMed]
  • 10. Ascherio A, Munger KL. Epstein-barr virus infection and multiple sclerosis: a review. J Neuroimmune Pharmacol. 2010; 5(3): 271-7[DOI][PubMed]
  • 11. Ruprecht K. [Multiple sclerosis and Epstein-Barr virus : new developments and perspectives]. Nervenarzt. 2008; 79(4): 399-407[DOI][PubMed]
  • 12. Levin LI, Munger KL, O'Reilly EJ, Falk KI, Ascherio A. Primary infection with the Epstein-Barr virus and risk of multiple sclerosis. Ann Neurol. 2010; 67(6): 824-30[DOI][PubMed]
  • 13. Levin LI, Munger KL, Rubertone MV, Peck CA, Lennette ET, Spiegelman D, et al. Temporal relationship between elevation of epstein-barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis. JAMA. 2005; 293(20): 2496-500[DOI][PubMed]
  • 14. Haahr S, Plesner AM, Vestergaard BF, Hollsberg P. A role of late Epstein-Barr virus infection in multiple sclerosis. Acta Neurol Scand. 2004; 109(4): 270-5[PubMed]
  • 15. DeLorenze GN, Munger KL, Lennette ET, Orentreich N, Vogelman JH, Ascherio A. Epstein-Barr virus and multiple sclerosis: evidence of association from a prospective study with long-term follow-up. Arch Neurol. 2006; 63(6): 839-44[DOI][PubMed]
  • 16. Ascherio A, Munger KL. Environmental risk factors for multiple sclerosis. Part I: the role of infection. Ann Neurol. 2007; 61(4): 288-99[DOI][PubMed]
  • 17. Lennette ET, Rymo L, Yadav M, Masucci G, Merk K, Timar L, et al. Disease-related differences in antibody patterns against EBV-encoded nuclear antigens EBNA 1, EBNA 2 and EBNA 6. Eur J Cancer. 1993; 29A(11): 1584-9[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments