Jundishapur Journal of Microbiology

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Fresh Garlic Extract Enhances the Antimicrobial Activities of Antibiotics on Resistant Strains in Vitro

Guoliang Li 1 , Xudong Ma 1 , Lisha Deng 2 , Xixi Zhao 2 , Yuejiao Wei 1 , Zhongyang Gao 2 , Jing Jia 1 , Jiru Xu 2 , * and Chaofeng Sun 1
Authors Information
1 The First Affiliated Hospital, Xi’an Jiaotong University Health Science Center, Xi’an, China
2 Department of Pathogen Biology and Immunology, College of Basic Medicine, Xi’an Jiaotong University Health Science Center, Xi’an, China
Article information
  • Jundishapur Journal of Microbiology: May 01, 2015, 8 (5); e14814
  • Published Online: May 31, 2015
  • Article Type: Research Article
  • Received: September 13, 2013
  • Revised: April 13, 2014
  • Accepted: April 20, 2014
  • DOI: 10.5812/jjm.14814

To Cite: Li G, Ma X, Deng L, Zhao X, Wei Y, et al. Fresh Garlic Extract Enhances the Antimicrobial Activities of Antibiotics on Resistant Strains in Vitro, Jundishapur J Microbiol. 2015 ; 8(5):e14814. doi: 10.5812/jjm.14814.

Abstract
Copyright © 2015, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Mane A, Gaikwad S, Bembalkar S, Risbud A. Increased expression of virulence attributes in oral Candida albicans isolates from human immunodeficiency virus-positive individuals. J Med Microbiol. 2012; 61: 285-90[DOI][PubMed]
  • 2. Balasubramanian D, Kong KF, Jayawardena SR, Leal SM, Sautter RT, Mathee K. Co-regulation of {beta}-lactam resistance, alginate production and quorum sensing in Pseudomonas aeruginosa. J Med Microbiol. 2011; 60: 147-56[DOI][PubMed]
  • 3. Datta P, Gulati N, Singla N, Rani Vasdeva H, Bala K, Chander J, et al. Evaluation of various methods for the detection of meticillin-resistant Staphylococcus aureus strains and susceptibility patterns. J Med Microbiol. 2011; 60: 1613-6[DOI][PubMed]
  • 4. Watamoto T, Samaranayake LP, Egusa H, Yatani H, Seneviratne CJ. Transcriptional regulation of drug-resistance genes in Candida albicans biofilms in response to antifungals. J Med Microbiol. 2011; 60: 1241-7[DOI][PubMed]
  • 5. Strateva T, Yordanov D. Pseudomonas aeruginosa - a phenomenon of bacterial resistance. J Med Microbiol. 2009; 58: 1133-48[DOI][PubMed]
  • 6. Patel M, Shackleton JT, Coogan MM. Effect of antifungal treatment on the prevalence of yeasts in HIV-infected subjects. J Med Microbiol. 2006; 55: 1279-84[DOI][PubMed]
  • 7. Smith K, Hunter IS. Efficacy of common hospital biocides with biofilms of multi-drug resistant clinical isolates. J Med Microbiol. 2008; 57: 966-73[DOI][PubMed]
  • 8. De Groote VN, Fauvart M, Kint CI, Verstraeten N, Jans A, Cornelis P, et al. Pseudomonas aeruginosa fosfomycin resistance mechanisms affect non-inherited fluoroquinolone tolerance. J Med Microbiol. 2011; 60: 329-36[DOI][PubMed]
  • 9. Shuford JA, Steckelberg JM, Patel R. Effects of fresh garlic extract on Candida albicans biofilms. Antimicrob Agents Chemother. 2005; 49(1): 473[DOI][PubMed]
  • 10. Low CF, Chong PP, Yong PV, Lim CS, Ahmad Z, Othman F. Inhibition of hyphae formation and SIR2 expression in Candida albicans treated with fresh Allium sativum (garlic) extract. J Appl Microbiol. 2008; 105(6): 2169-77[DOI][PubMed]
  • 11. Tsao SM, Yin MC. In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils. J Med Microbiol. 2001; 50(7): 646-9[PubMed]
  • 12. Tsao SM, Liu WH, Yin MC. Two diallyl sulphides derived from garlic inhibit meticillin-resistant Staphylococcus aureus infection in diabetic mice. J Med Microbiol. 2007; 56: 803-8[DOI][PubMed]
  • 13. Nidadavolu P, Amor W, Tran PL, Dertien J, Colmer-Hamood JA, Hamood AN. Garlic ointment inhibits biofilm formation by bacterial pathogens from burn wounds. J Med Microbiol. 2012; 61: 662-71[DOI][PubMed]
  • 14. Cutler RR, Wilson P. Antibacterial activity of a new, stable, aqueous extract of allicin against methicillin-resistant Staphylococcus aureus. Br J Biomed Sci. 2004; 61(2): 71-4[PubMed]
  • 15. Arzanlou M, Bohlooli S. Inhibition of streptolysin O by allicin - an active component of garlic. J Med Microbiol. 2010; 59: 1044-9[DOI][PubMed]
  • 16. An M, Shen H, Cao Y, Zhang J, Cai Y, Wang R, et al. Allicin enhances the oxidative damage effect of amphotericin B against Candida albicans. Int J Antimicrob Agents. 2009; 33(3): 258-63[DOI][PubMed]
  • 17. Yousuf S, Ahmad A, Khan A, Manzoor N, Khan LA. Effect of garlic-derived allyl sulphides on morphogenesis and hydrolytic enzyme secretion in Candida albicans. Med Mycol. 2011; 49(4): 444-8[DOI][PubMed]
  • 18. Klein E, Smith DL, Laxminarayan R. Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005. Emerg Infect Dis. 2007; 13(12): 1840-6[DOI][PubMed]
  • 19. Sista RR, Oda G, Barr J. Methicillin-resistant Staphylococcus aureus infections in ICU patients. Anesthesiol Clin North America. 2004; 22(3): 405-35[DOI][PubMed]
  • 20. Jefferies JM, Cooper T, Yam T, Clarke SC. Pseudomonas aeruginosa outbreaks in the neonatal intensive care unit--a systematic review of risk factors and environmental sources. J Med Microbiol. 2012; 61: 1052-61[DOI][PubMed]
  • 21. Sjoberg BM, Torrents E. Shift in ribonucleotide reductase gene expression in Pseudomonas aeruginosa during infection. Infect Immun. 2011; 79(7): 2663-9[DOI][PubMed]
  • 22. Amini S, Hottes AK, Smith LE, Tavazoie S. Fitness landscape of antibiotic tolerance in Pseudomonas aeruginosa biofilms. PLoS Pathog. 2011; 7(10)[DOI][PubMed]
  • 23. Perumal D, Lim CS, Sakharkar KR, Sakharkar MK. Differential genome analyses of metabolic enzymes in Pseudomonas aeruginosa for drug target identification. In Silico Biol. 2007; 7(4-5): 453-65[PubMed]
  • 24. Bjarnsholt T, Jensen PO, Rasmussen TB, Christophersen L, Calum H, Hentzer M, et al. Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology. 2005; 151: 3873-80[DOI][PubMed]
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