Jundishapur Journal of Microbiology

Published by: Kowsar

Frequency of PER, VEB, SHV, TEM and CTX-M Genes in Resistant Strains of Pseudomonas aeruginosa Producing Extended Spectrum β-Lactamases

Mohmmad Bokaeian 1 , 2 , Shahram Shahraki Zahedani 1 , Morteza Soltanian Bajgiran 1 , * and Alireza Ansari Moghaddam 3
Authors Information
1 Department of Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran
2 Research Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran
3 Health Promotion Research Centre, Zahedan University of Medical Sciences, Zahedan, IR Iran
Article information
  • Jundishapur Journal of Microbiology: January 01, 2015, 8 (1); e13783
  • Published Online: December 8, 2014
  • Article Type: Research Article
  • Received: August 27, 2013
  • Revised: January 18, 2014
  • Accepted: January 21, 2014
  • DOI: 10.5812/jjm.13783

To Cite: Bokaeian M, Shahraki Zahedani S, Soltanian Bajgiran M, Ansari Moghaddam A. Frequency of PER, VEB, SHV, TEM and CTX-M Genes in Resistant Strains of Pseudomonas aeruginosa Producing Extended Spectrum β-Lactamases, Jundishapur J Microbiol. 2015 ; 8(1):e13783. doi: 10.5812/jjm.13783.

Copyright © 2014, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Palmer GC, Palmer KL, Jorth PA, Whiteley M. Characterization of the Pseudomonas aeruginosa transcriptional response to phenylalanine and tyrosine. J Bacteriol. 2010; 192(11): 2722-8[DOI][PubMed]
  • 2. Bonomo RA, Szabo D. Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa. Clin Infect Dis. 2006; 43 Suppl 2-56[DOI][PubMed]
  • 3. Lister PD, Wolter DJ, Hanson ND. Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin Microbiol Rev. 2009; 22(4): 582-610[DOI][PubMed]
  • 4. Shacheraghi F, Shakibaie MR, Noveiri H. Molecular Identification of ESBL genes blaGES-1, blaVEB-1, blaCTX-M blaOXA-1, blaOXA-4, blaOXA-10 and blaPER-1 in Pseudomonas aeruginosa strains isolated from burn patients by PCR, RFLP and sequencing techniques. Int J Biol life Sci. 2010; 3(6): 138-42
  • 5. Paterson DL. Extended-spectrum beta-lactamases: the European experience. Curr Opin Infect Dis. 2001; 14(6): 697-701[PubMed]
  • 6. Bali E. B., Acik L., Sultan N.. Phenotypic and molecular characterization of SHV,TEM, CTX-M and extended-spectrum b-lactamase produced by Escherichia coli, Acinobacter baumannii and Klebsiella isolates in a Turkish hospital. Afr J Microbiol Res. 2010; 4(8): 650-4
  • 7. Bae IK, Jang SJ, Kim J, Jeong SH, Cho B, Lee K. Interspecies dissemination of the bla gene encoding PER-1 extended-spectrum beta-lactamase. Antimicrob Agents Chemother. 2011; 55(3): 1305-7[DOI][PubMed]
  • 8. Woodford N, Zhang J, Kaufmann ME, Yarde S, Tomas Mdel M, Faris C, et al. Detection of Pseudomonas aeruginosa isolates producing VEB-type extended-spectrum beta-lactamases in the United Kingdom. J Antimicrob Chemother. 2008; 62(6): 1265-8[DOI][PubMed]
  • 9. Jain A, Mondal R. TEM & SHV genes in extended spectrum beta-lactamase producing Klebsiella species beta their antimicrobial resistance pattern. Indian J Med Res. 2008; 128(6): 759-64[PubMed]
  • 10. Clinical Laboratory Standards Institute . Performance standards for antimicrobial disk susceptibility testing: approved standard. 2012;
  • 11. Tavajjohi Z, Moniri R, Khorshidi A. Detection and characterization of multidrug resistance and extended-spectrum-beta-lactamase-producing (ESBLS) Pseudomonas aeruginosa isolates in teaching hospital. African J Microbiol Res. 2011; 5(20): 3223-8
  • 12. European Committee on Antimicrobial Susceptibility Testing . EUCAST guidelines for detection of resistance mechanisms and specific resistances of clinical and/or epidemiological importance 2012;
  • 13. Weldhagen GF, Poirel L, Nordmann P. Ambler class A extended-spectrum beta-lactamases in Pseudomonas aeruginosa: novel developments and clinical impact. Antimicrob Agents Chemother. 2003; 47(8): 2385-92[PubMed]
  • 14. Dashti AA, Jadaon MM, Gomaa HH, Noronha B, Udo EE. Transmission of a Klebsiella pneumoniae clone harbouring genes for CTX-M-15-like and SHV-112 enzymes in a neonatal intensive care unit of a Kuwaiti hospital. J Med Microbiol. 2010; 59: 687-92[DOI][PubMed]
  • 15. Lim KT, Yasin RM, Yeo CC, Puthucheary SD, Balan G, Maning N, et al. Genetic fingerprinting and antimicrobial susceptibility profiles of Pseudomonas aeruginosa hospital isolates in Malaysia. J Microbiol Immunol Infect. 2009; 42(3): 197-209[PubMed]
  • 16. Mirsalehian A, Feizabadi M, Nakhjavani FA, Jabalameli F, Goli H, Kalantari N. Detection of VEB-1, OXA-10 and PER-1 genotypes in extended-spectrum beta-lactamase-producing Pseudomonas aeruginosa strains isolated from burn patients. Burns. 2010; 36(1): 70-4[DOI][PubMed]
  • 17. Ullah F, Malik SA, Ahmed J. Antimicrobial susceptibility and ESBL prevalence in Pseudomonas aeruginosa isolated from burn patients in the North West of Pakistan. Burns. 2009; 35(7): 1020-5[DOI][PubMed]
  • 18. Chanawong A, M'Zali FH, Heritage J, Lulitanond A, Hawkey PM. SHV-12, SHV-5, SHV-2a and VEB-1 extended-spectrum beta-lactamases in Gram-negative bacteria isolated in a university hospital in Thailand. J Antimicrob Chemother. 2001; 48(6): 839-52[PubMed]
  • 19. Aggarwal R, Chaudhary U, Bala K. Detection of extended-spectrum beta-lactamase in Pseudomonas aeruginosa. Indian J Pathol Microbiol. 2008; 51(2): 222-4[PubMed]
  • 20. Song JS, Jeon JH, Lee JH, Jeong SH, Jeong BC, Kim SJ, et al. Molecular characterization of TEM-type beta-lactamases identified in cold-seep sediments of Edison Seamount (south of Lihir Island, Papua New Guinea). J Microbiol. 2005; 43(2): 172-8[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments