Jundishapur Journal of Microbiology

Published by: Kowsar

The Effect of Aqueous Extract of Glycyrrhiza glabra on Herpes Simplex Virus 1

Masoud Sabouri Ghannad 1 , * , Avid Mohammadi 1 , Sohayla Safiallahy 1 , Javad Faradmal 2 , Mona Azizi 1 and Zohreh Ahmadvand 1
Authors Information
1 Research Center for Molecular Medicine, Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran
2 Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran
Article information
  • Jundishapur Journal of Microbiology: July 01, 2014, 7 (7); e11616
  • Published Online: July 1, 2014
  • Article Type: Research Article
  • Received: April 24, 2013
  • Revised: June 16, 2013
  • Accepted: July 11, 2013
  • DOI: 10.5812/jjm.11616

To Cite: Sabouri Ghannad M, Mohammadi A, Safiallahy S, Faradmal J, Azizi M, et al. The Effect of Aqueous Extract of Glycyrrhiza glabra on Herpes Simplex Virus 1, Jundishapur J Microbiol. 2014 ; 7(7):e11616. doi: 10.5812/jjm.11616.

Abstract
Copyright © 2014, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Karamoddini MK. Antiviral activities of aerial subsets of Artemisia species against Herpes Simplex virus type 1 (HSV1) in vitro. Asian Biomed. 2011; 5(1): 63
  • 2. Wilson SS, Fakioglu E, Herold BC. Novel approaches in fighting herpes simplex virus infections. Expert Rev Anti Infect Ther. 2009; 7(5): 559-68[DOI][PubMed]
  • 3. Fiore C, Eisenhut M, Krausse R, Ragazzi E, Pellati D, Armanini D, et al. Antiviral effects of Glycyrrhiza species. Phytother Res. 2008; 22(2): 141-8[DOI][PubMed]
  • 4. Isbrucker RA, Burdock GA. Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin. Regul Toxicol Pharmacol. 2006; 46(3): 167-92[DOI][PubMed]
  • 5. Pompei R, Flore O, Marccialis MA, Pani A, Loddo B. Glycyrrhizic acid inhibits virus growth and inactivates virus particles. Nature. 1979; 281(5733): 689-90[PubMed]
  • 6. Chattopadhyay D, Das S, Chakraborty S, Bhattacharya SK. Ethnomedicines for the development of anti-herpesvirus agents. Ethnomedicine: A Source of Complementary Therapeutic. 2010; 117
  • 7. Ziyaeyan M, Japoni A, Roostaee MH, Salehi S, Soleimanjahi H. A serological survey of Herpes Simplex Virus type 1 and 2 immunity in pregnant women at labor stage in Tehran, Iran. Pak J Biol Sci. 2007; 10(1): 148-51[PubMed]
  • 8. Emami SA, Tayarani NZ, Sabouri GHM, Khajeh Karamaldini P, Khajeh Karamaldini M. Antiviral activity of obtained extracts from different parts of cupressus sempervirens against herpes simplex virus type. IJBMS. 2009;
  • 9. Haji Mahdipour H, Amanzadeh Y, Hasanlou T, Shekarchi M, Abedi Z, Pirali Hamedani M. Investigating on the Quality of Wild Licorice Roots Collected from Different Regions of Iran. J Med Plants. 2008; 106
  • 10. Flint SJ, Enquist LW, Racaniello VR, Skalka AM. Virus cultivation, detection, and genetics. Principles of Virology: Molecular Biology, Pathogenesis, and Control of Animal Viruses. 2004; 2: 26-62
  • 11. Wittschier N, Faller G, Hensel A. Aqueous extracts and polysaccharides from liquorice roots (Glycyrrhiza glabra L.) inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Ethnopharmacol. 2009; 125(2): 218-23[DOI][PubMed]
  • 12. Partridge M, Poswillo DE. Topical carbenoxolone sodium in the management of herpes simplex infection. Br J Oral Maxillofac Surg. 1984; 22(2): 138-45[PubMed]
  • 13. Kuo YC, Kuo YH, Lin YL, Tsai WJ. Yatein from Chamaecyparis obtusa suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression. Antiviral Res. 2006; 70(3): 112-20[DOI][PubMed]
  • 14. Ren Z, Zhang CH, Wang LJ, Cui YX, Qi RB, Yang CR, et al. In vitro anti-viral activity of the total alkaloids from Tripterygium hypoglaucum against herpes simplex virus type 1. Virol Sin. 2010; 25(2): 107-14[DOI][PubMed]
  • 15. Hirabayashi K, Iwata S, Matsumoto H, Mori T, Shibata S, Baba M, et al. Antiviral activities of glycyrrhizin and its modified compounds against human immunodeficiency virus type 1 (HIV-1) and herpes simplex virus type 1 (HSV-1) in vitro. Chem Pharm Bull (Tokyo). 1991; 39(1): 112-5[PubMed]
  • 16. Pompei R, Pani A, Flore O, Marcialis MA, Loddo B. Antiviral activity of glycyrrhizic acid. Experientia. 1980; 36(3): 304[PubMed]
  • 17. Utsunomiya T, Kobayashi M, Herndon DN, Pollard RB, Suzuki F. Glycyrrhizin (20 beta-carboxy-11-oxo-30-norolean-12-en-3 beta-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid) improves the resistance of thermally injured mice to opportunistic infection of herpes simplex virus type 1. Immunol Lett. 1995; 44(1): 59-66[PubMed]
  • 18. Shibata N, Shimokawa T, Jiang Z, Jeong Y, Ohno T, Kimura G, et al. Characteristics of intestinal absorption and disposition of glycyrrhizin in mice. Biopharm Drug Dispos. 2000; 21(3): 95-101[PubMed]
  • 19. Baltina LA. Chemical modification of glycyrrhizic acid as a route to new bioactive compounds for medicine. Curr Med Chem. 2003; 10(2): 155-71[PubMed]
  • 20. van Rossum TG, Vulto AG, de Man RA, Brouwer JT, Schalm SW. Review article: glycyrrhizin as a potential treatment for chronic hepatitis C. Aliment Pharmacol Ther. 1998; 12(3): 199-205[PubMed]
  • 21. Cohen JI. Licking latency with licorice. J Clin Invest. 2005; 115(3): 591-3[DOI][PubMed]
  • 22. Pompei R, Paghi L, Ingianni A, Uccheddu P. Glycyrrhizic acid inhibits influenza virus growth in embryonated eggs. Microbiologica. 1983; 6(3): 247-50[PubMed]
  • 23. Utsunomiya T, Kobayashi M, Pollard RB, Suzuki F. Glycyrrhizin, an active component of licorice roots, reduces morbidity and mortality of mice infected with lethal doses of influenza virus. Antimicrob Agents Chemother. 1997; 41(3): 551-6[PubMed]
  • 24. Lampi G, Deidda D, Pinza M, Pompei R. Enhancement of anti-herpetic activity of glycyrrhizic acid by physiological proteins. Antivir Chem Chemother. 2001; 12(2): 125-31[PubMed]
  • 25. Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr HW. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Lancet. 2003; 361(9374): 2045-6[PubMed]
  • 26. Crance JM, Scaramozzino N, Jouan A, Garin D. Interferon, ribavirin, 6-azauridine and glycyrrhizin: antiviral compounds active against pathogenic flaviviruses. Antiviral Res. 2003; 58(1): 73-9[PubMed]
  • 27. Briolant S, Garin D, Scaramozzino N, Jouan A, Crance JM. In vitro inhibition of Chikungunya and Semliki Forest viruses replication by antiviral compounds: synergistic effect of interferon-alpha and ribavirin combination. Antiviral Res. 2004; 61(2): 111-7[PubMed]
  • 28. Hoever G, Baltina L, Michaelis M, Kondratenko R, Baltina L, Tolstikov GA, et al. Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus. J Med Chem. 2005; 48(4): 1256-9[DOI][PubMed]
  • 29. Takei M, Kobayashi M, Li XD, Pollard RB, Suzuki F. Glycyrrhizin inhibits R5 HIV replication in peripheral blood monocytes treated with 1-methyladenosine. Pathobiology. 2005; 72(3): 117-23[DOI][PubMed]
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