Jundishapur Journal of Microbiology

Published by: Kowsar

Statins and Postoperative Infections: A Randomized Clinical Trial

Shervin Shokouhi 1 , * , Ilad Alavi Darazam 1 , 2 , Giv Sharifi 3 , Latif Gachkar 4 , Anahita Amirsardari 4 and Mohammad Samadian 3
Authors Information
1 Department of Infectious Disease, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
2 National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
3 Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
4 Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Article information
  • Jundishapur Journal of Microbiology: April 01, 2014, 7 (4); e9456
  • Published Online: April 1, 2014
  • Article Type: Research Article
  • Received: December 4, 2012
  • Revised: April 25, 2013
  • Accepted: May 5, 2013
  • DOI: 10.5812/jjm.9456

To Cite: Shokouhi S, Alavi Darazam I, Sharifi G, Gachkar L, Amirsardari A, et al. Statins and Postoperative Infections: A Randomized Clinical Trial, Jundishapur J Microbiol. 2014 ; 7(4):e9456. doi: 10.5812/jjm.9456.

Abstract
Copyright © 2014, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. DeFrances CJ, Cullen KA, Kozak LJ. National Hospital Discharge Survey: 2005 annual summary with detailed diagnosis and procedure data. Vital Health Stat 13. 2007; (165): 1-209[PubMed]
  • 2. National Nosocomial Infections Surveillance S. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control. 2004; 32(8): 470-85[DOI][PubMed]
  • 3. Martone WJ, Nichols RL. Recognition, prevention, surveillance, and management of surgical site infections: introduction to the problem and symposium overview. Clin Infect Dis. 2001; 33 Suppl 2-8[DOI][PubMed]
  • 4. Liappis AP, Kan VL, Rochester CG, Simon GL. The effect of statins on mortality in patients with bacteremia. Clin Infect Dis. 2001; 33(8): 1352-7[DOI][PubMed]
  • 5. Khurana V, Bejjanki HR, Caldito G, Owens MW. Statins reduce the risk of lung cancer in humans: a large case-control study of US veterans. Chest. 2007; 131(5): 1282-8[DOI][PubMed]
  • 6. Tonelli M, Moye L, Sacks FM, Cole T, Curhan GC, et al. Effect of pravastatin on loss of renal function in people with moderate chronic renal insufficiency and cardiovascular disease. J Am Soc Nephrol. 2003; 14(6): 1605-13[PubMed]
  • 7. Terblanche M, Almog Y, Rosenson RS, Smith TS, Hackam DG. Statins and sepsis: multiple modifications at multiple levels. Lancet Infect Dis. 2007; 7(5): 358-68[DOI][PubMed]
  • 8. Rosenson RS. Statins: Possible non-cardiovascular benefits. 2011;
  • 9. van den Hoek HL, Bos WJ, de Boer A, van de Garde EM. Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials. Bmj. 2011; 343[DOI][PubMed]
  • 10. Hackam DG, Mamdani M, Li P, Redelmeier DA. Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis. Lancet. 2006; 367(9508): 413-8[DOI][PubMed]
  • 11. Becker K, Tanzi P, Kalil A, Shibata D, Cain K. Early statin use is associated with increased risk of infection after stroke. J Stroke Cerebrovasc Dis. 2013; 22(1): 66-71[DOI][PubMed]
  • 12. Newman CB, Szarek M, Colhoun HM, Betteridge DJ, Durrington PN, Hitman GA, et al. The safety and tolerability of atorvastatin 10 mg in the Collaborative Atorvastatin Diabetes Study (CARDS). Diab Vasc Dis Res. 2008; 5(3): 177-83[DOI][PubMed]
  • 13. Tleyjeh IM, Kashour T, Hakim FA, Zimmerman VA, Erwin PJ, Sutton AJ, et al. Statins for the prevention and treatment of infections: a systematic review and meta-analysis. Arch Intern Med. 2009; 169(18): 1658-67[DOI][PubMed]
  • 14. Coleman CI, Lucek DM, Hammond J, White CM. Preoperative statins and infectious complications following cardiac surgery. Curr Med Res Opin. 2007; 23(8): 1783-90[DOI][PubMed]
  • 15. Hauer-Jensen M, Fort C, Mehta JL, Fink LM. Influence of statins on postoperative wound complications after inguinal or ventral herniorrhaphy. Hernia. 2006; 10(1): 48-52[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments