Jundishapur Journal of Microbiology

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Production of Avermectin B1b From Streptomyces avermitilis 41445 by Batch Submerged Fermentation

Samia Siddique 1 , * , Quratulain Syed 2 , Ahmad Adnan 1 , Muhammad Nadeem 2 , Muhammad Irfan 2 and Fahim Ashraf Qureshi 3
Authors Information
1 Department of Chemistry, Government College University, Lahore, Pakistan
2 Food and Biotechnology Research Center, PCSIR Laboratories Complex, Lahore, Pakistan
3 Office of Research, Innovation and Commercialization, Comsats Institute of Information and Technology, Islamabad, Pakistan
Article information
  • Jundishapur Journal of Microbiology: October 01, 2013, 6 (8); e7198
  • Published Online: October 1, 2013
  • Article Type: Research Article
  • Received: July 10, 2012
  • Revised: August 18, 2012
  • Accepted: September 30, 2012
  • DOI: 10.5812/jjm.7198

To Cite: Siddique S, Syed Q, Adnan A, Nadeem M, Irfan M, et al. Production of Avermectin B1b From Streptomyces avermitilis 41445 by Batch Submerged Fermentation, Jundishapur J Microbiol. 2013 ; 6(8):e7198. doi: 10.5812/jjm.7198.

Abstract
Copyright © 2013, Ahvaz Jundishapur University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Jill S, Richard HB. Mutagenic DNA repair in Streptomycetes. J Proc Natl Acad Sci . 1984; 82: 1180-1183
  • 2. Pinna LA, Lorini M, Moret V, Siliprandi N. Effect of oligomycin and succinate on mitochondrial metabolism of adenine nucleotides. Biochim Biophys Acta (BBA) - Bioenergetics. 1967; 143(1): 18-25[DOI]
  • 3. Burg RW, Miller BM, Baker EE, Birnbaum J, Currie SA, Hartman R, et al. Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation. Antimicrob Agents Chemother. 1979; 15(3): 361-367[DOI]
  • 4. Ikeda Haruo, Omura Satoshi. Control of Avermectin Biosynthesis in Streptomyces avermitilis for the Selective Production of a Useful Component. J Antibiot. 1995; 48(7): 549-562[DOI]
  • 5. Zimmermann HF, John GT, Trauthwein H, Dingerdissen U, Huthmacher K. Rapid evaluation of oxygen and water permeation through microplate sealing tapes. Biotechnol Prog. 2003; 19(3): 1061-3[DOI][PubMed]
  • 6. Yong JH, Byeon WH. Alternative production of avermectin components in Streptomyces avermitilis by gene replacement. J Microbiol. 2005; 43(3): 277-84[PubMed]
  • 7. Bloomquist JR. Toxicology, mode of action and target site-mediated resistance to insecticides acting on chloride channels. Comp Biochem Physiol C. 1993; 106(2): 301-14[PubMed]
  • 8. Yu J, Liu Q, Liu X, Sun Q, Yan J, Qi X, et al. Effect of liquid culture requirements on antifungal antibiotic production by Streptomyces rimosus MY02. Bioresour Technol. 2008; 99(6): 2087-91[DOI][PubMed]
  • 9. Purama RK, Goyal A. Screening and optimization of nutritional factors for higher dextransucrase production by Leuconostocmesenteroides NRRL B-640 using statistical approach. Bioresour Technol. 2008; 99(15): 7108-14[DOI][PubMed]
  • 10. Yuan LL, Li YQ, Wang Y, Zhang XH, Xu YQ. Optimization of critical medium components using response surface methodology for phenazine-1-carboxylic acid production by Pseudomonas sp. M-18Q. J Biosci Bioeng. 2008; 105(3): 232-7[DOI][PubMed]
  • 11. Jonsbu Einar, McIntyre Mhairi, Nielsen Jens. The influence of carbon sources and morphology on nystatin production by Streptomyces noursei. J Biotechnol. 2002; 95(2): 133-144[DOI]
  • 12. Gupte TE, Naik SR. Optimisation of nutritional requirements and process control parameters for the production of HA-2-91, a new tetraene polyene antibiotic. Hindustan Antibiot Bull. 1998; 40(1-4): 5-13[PubMed]
  • 13. Jia B, Jin ZH, Mei LH. Medium optimization based on statistical methodologies for pristinamycins production by Streptomyces pristinaespiralis. Appl Biochem Biotechnol. 2008; 144(2): 133-43[PubMed]
  • 14. Syed DG, Lee JC, Li WJ, Kim CJ, Agasar D. Production, characterization and application of keratinase from Streptomyces gulbargensis. Bioresour Technol. 2009; 100(5): 1868-71[DOI][PubMed]
  • 15. Voelker F, Altaba S. Nitrogen source governs the patterns of growth and pristinamycin production in 'Streptomyces pristinaespiralis'. Microbiology. 2001; 147: 2447-59[PubMed]
  • 16. Gill P. Effect of media supplements and culture conditions on inulinase production by an actinomycete strain. Bioresour Technol. 2003; 87(3): 359-362[DOI]
  • 17. Tuncer M, Kuru A, Isikli M, Sahin N, Celenk FG. Optimization of extracellular endoxylanase, endoglucanase and peroxidase production by Streptomyces sp. F2621 isolated in Turkey. J Appl Microbiol. 2004; 97(4): 783-91[DOI][PubMed]
  • 18. Suutari M, Lignell U, Hyvarinen A, Nevalainen A. Media for cultivation of indoor streptomycetes. J Microbiol Methods. 2002; 51(3): 411-6[PubMed]
  • 19. Zhinan X, Peilin C. Enhanced production of avermectin B1a by medium optimization and glucose feeding with Streptomyces avermilitis. Bioprocess Engineering. 1999; 20(1): 67-71[DOI]
  • 20. Kitani S, Ikeda H, Sakamoto T, Noguchi S, Nihira T. Characterization of a regulatory gene, aveR, for the biosynthesis of avermectin in Streptomyces avermitilis. Appl Microbiol Biotechnol. 2009; 82(6): 1089-96[DOI][PubMed]
  • 21. Chen Z, Wen J, Song Y, Wen Y, Li JL. Enhancement and selective production of avermectin B by recombinants of Streptomyces avermitilis via intraspecific protoplast fusion. Chinese Science Bulletin. 2007; 52(5): 616-622
  • 22. Lazim H, Mankai H, Slama N, Barkallah I, Limam F. Production and optimization of thermophilic alkaline protease in solid-state fermentation by Streptomyces sp. CN902. J Ind Microbiol Biotechnol. 2009; 36(4): 531-537[DOI]
  • 23. Chatterjee S, Vining LC. Nutrient utilization in actinomycetes. Induction of alpha-glucosidases in Streptomyces venezuelae. Can J Microbiol. 1981; 27(7): 639-45[PubMed]
  • 24. Gesheva V, Ivanova V, Gesheva R. Effects of nutrients on the production of AK-111-81 macrolide antibiotic by Streptomyces hygroscopicus. Microbiol Res. 2005; 160(3): 243-8[DOI][PubMed]
  • 25. Soliveri J, Mendoza A, Arias MA. Effect of different nutrients on the production of polyene antibiotics PA-5 and PA-7 by Streptoverticillium spp. 43/16 in chemically defined media. J Appl Microbiol Biotechnol. 1988; 28: 254-257
  • 26. Schulman MD, Valentino D, Streicher S, Ruby C. "Streptomyces avermitilis" mutants defective in methylation of avermectins. Antimicrob Agents Chemother. 1987; 31(5): 744-747[DOI]
  • 27. Schulman MD, Ruby C. Methylation of demethylavermectins. Antimicrobial Agents and Chemotherapy. 1987; 31(6): 964-965[DOI]
  • 28. Gao H, Liu M, Liu J, Dai H, Zhou X, Liu X, et al. Medium optimization for the production of avermectin B1a by Streptomyces avermitilis 14-12A using response surface methodology. Bioresour Technol. 2009; 100(17): 4012-6[DOI][PubMed]
  • 29. Aikawa M, Lopes-Shikida SAR, Lemos MF, Pradella JGC, Padilla G. Screening of spontaneous and induced mutants in Streptomyces avermitilis enhances avermectin production. Appl Microbiol Biotechnol. 1999; 52(4): 558-562[DOI]
  • 30. Yin P, Wang YH, Zhang SL, Chu J, Zhuang YP, Chen N, et al. Effect of mycelial morphology on bioreactor performance and avermectin production of Streptomyces avermitilis in submerged cultivations. J Chin Institute Chem Engineers. 2008; 39(6): 609-615[DOI]
  • 31. Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L, et al. Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis. Appl Microbiol Biotechnol. 2011; 92(2): 337-345[DOI]
  • 32. Wang LY, Huang ZL, Li G, Zhao HX, Xing XH, Sun WT, et al. Novel mutation breeding method for Streptomyces avermitilis using an atmospheric pressure glow discharge plasma. J Appl Microbiol. 2010; 108(3): 851-8[DOI][PubMed]
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